Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Erin Trachet"'
Autor:
Patrick W. Vincent, Haile Tecle, Helen T. Lee, Jianxin Yang, Deborah A. Baker, Daniel J. Lettiere, Alex J. Bridges, Jessica E. Reed, R. Thomas Winters, Karen E. Sexton, Kevin M. Schlosser, Stephen A. Fakhoury, Cho-Ming Loi, Tong Zhu, David W. Fry, James M. Nelson, Danielle M. Amato, Teresa A. Ellis, Patricia J. Harvey, Amy M. Delaney, Erin Trachet, Paul A. Ellis, Irene W. Althaus, Kenneth E. Hook, Andrea J. Gonzales
Supplementary Fig. S3 from Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a40c0cb9dee2febea61bbf447bdf801
https://doi.org/10.1158/1535-7163.22483889
https://doi.org/10.1158/1535-7163.22483889
Autor:
Patrick W. Vincent, Haile Tecle, Helen T. Lee, Jianxin Yang, Deborah A. Baker, Daniel J. Lettiere, Alex J. Bridges, Jessica E. Reed, R. Thomas Winters, Karen E. Sexton, Kevin M. Schlosser, Stephen A. Fakhoury, Cho-Ming Loi, Tong Zhu, David W. Fry, James M. Nelson, Danielle M. Amato, Teresa A. Ellis, Patricia J. Harvey, Amy M. Delaney, Erin Trachet, Paul A. Ellis, Irene W. Althaus, Kenneth E. Hook, Andrea J. Gonzales
Signaling through the erbB receptor family of tyrosine kinases contributes to the proliferation, differentiation, migration, and survival of a variety of cell types. Abnormalities in members of this receptor family have been shown to play a role in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1992a9e6a0fff9d2a73c053cb1cf91a6
https://doi.org/10.1158/1535-7163.c.6531266.v1
https://doi.org/10.1158/1535-7163.c.6531266.v1
Autor:
Patrick W. Vincent, Haile Tecle, Helen T. Lee, Jianxin Yang, Deborah A. Baker, Daniel J. Lettiere, Alex J. Bridges, Jessica E. Reed, R. Thomas Winters, Karen E. Sexton, Kevin M. Schlosser, Stephen A. Fakhoury, Cho-Ming Loi, Tong Zhu, David W. Fry, James M. Nelson, Danielle M. Amato, Teresa A. Ellis, Patricia J. Harvey, Amy M. Delaney, Erin Trachet, Paul A. Ellis, Irene W. Althaus, Kenneth E. Hook, Andrea J. Gonzales
Supplementary Fig. S4 from Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49237d65e427820be60eccc4c4e730d7
https://doi.org/10.1158/1535-7163.22483886
https://doi.org/10.1158/1535-7163.22483886
Autor:
Patrick W. Vincent, Haile Tecle, Helen T. Lee, Jianxin Yang, Deborah A. Baker, Daniel J. Lettiere, Alex J. Bridges, Jessica E. Reed, R. Thomas Winters, Karen E. Sexton, Kevin M. Schlosser, Stephen A. Fakhoury, Cho-Ming Loi, Tong Zhu, David W. Fry, James M. Nelson, Danielle M. Amato, Teresa A. Ellis, Patricia J. Harvey, Amy M. Delaney, Erin Trachet, Paul A. Ellis, Irene W. Althaus, Kenneth E. Hook, Andrea J. Gonzales
Supplementary Fig. S1 from Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d558a2ea8fa4224722f84320d263b3c
https://doi.org/10.1158/1535-7163.22483895.v1
https://doi.org/10.1158/1535-7163.22483895.v1
Publikováno v:
Cancer Research. 83:2402-2402
Genomic assault in the form of DNA double-strand breaks represents the most efficient mechanism by which radiotherapy mediates killing of cancer cells. In order to preserve cellular integrity and mitigate the adverse effects and complications arising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::427238ff64ed59172f5709834ed73653
https://doi.org/10.1158/1538-7445.am2023-2402
https://doi.org/10.1158/1538-7445.am2023-2402
Publikováno v:
Cancer Research. 83:41-41
Triple immunodeficient mouse models, that lack functional T cells, B cells, and natural killer cells, are necessary when evaluating human cancer cell growth and cell-based therapy activity, allowing for assessment without innate mouse immune system i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b684851acbe0cc3244cdef5c222d6416
https://doi.org/10.1158/1538-7445.am2023-41
https://doi.org/10.1158/1538-7445.am2023-41
Autor:
Erin Trachet, Scott Wise
Publikováno v:
Cancer Research. 83:37-37
Lung cancer remains a devastating cancer diagnosis around the world, resulting in 18% of all cancer-related deaths. Lung cancer often metastasizes to the brain, significantly reducing life expectancy. Up to 7% of patients with non-small cell lung can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba8e731f88b4a535f68d51140a8fa36
https://doi.org/10.1158/1538-7445.am2023-37
https://doi.org/10.1158/1538-7445.am2023-37
Publikováno v:
Cancer Research. 81:2921-2921
Preclinical oncology studies aim to model human disease in animal settings. To this effect, the site of tumor implant is thought to impact critical parameters that determine response to treatment. The more frequently used subcutaneous (SC) models hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad95b3606da070e12337eb6373ce5ae
https://doi.org/10.1158/1538-7445.am2021-2921
https://doi.org/10.1158/1538-7445.am2021-2921
Autor:
Patricia J. Harvey, Gonzales Andrea, Shannon Leigh Black, Jeff B. Smaill, Ken Hook, Florence O. McCarthy, Stephen Fakhoury, Adrian Blaser, Haile Tecle, Freddy Rivault, Tong Zhu, Brian D. Palmer, Kevin Matthew Schlosser, Jessica Elizabeth Reed, Karen Elaine Sexton, William A. Denny, Irene W. Althaus, R. Thomas Winters, Teresa Ellis, Helen Tsenwhei Lee, Andrew M. Thompson, Erin Trachet, Alexander James Bridges, Julie Ann Spicer, Paul A. Ellis
Publikováno v:
Journal of Medicinal Chemistry. 59:8103-8124
Structure-activity relationships for inhibition of erbB1, erbB2, and erbB4 were determined for a series of quinazoline- and pyrido[3,4-d]pyrimidine-based analogues of the irreversible pan-erbB inhibitor, canertinib. Cyclic amine bearing crotonamides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e41b02b5002130f3f1a0856c03fbdf
https://doi.org/10.1021/acs.jmedchem.6b00883
https://doi.org/10.1021/acs.jmedchem.6b00883
Publikováno v:
Cancer Research. 80:920-920
Radiotherapy (RT) is a highly utilized clinical treatment approach for certain types of breast cancer. The use of RT, in combination with checkpoint blockade, to prime and activate the immune system is an area of intensive research. Developing precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e14a242666190f244f13516fb77eb883
https://doi.org/10.1158/1538-7445.am2020-920
https://doi.org/10.1158/1538-7445.am2020-920