Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Erin Touchette"'
Autor:
Hari Krishna Ananthula, Scott Parker, Erin Touchette, R. Mark Buller, Gopi Patel, Daniel Kalman, Johanna S. Salzer, Nadia Gallardo-Romero, Victoria Olson, Inger K. Damon, Tessa Moir-Savitz, Larry Sallans, Milton H. Werner, Catherine M. Sherwin, Pankaj B. Desai
Publikováno v:
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Several tyrosine kinase inhibitors (TKIs) developed as anti-cancer drugs, also have anti-viral activity due to their ability to disrupt productive replication and dissemination in infected cells. Consequently, such drugs are attra
Externí odkaz:
https://doaj.org/article/83a53eda23e440079a5f5c240ec6da0b
Autor:
Larry Sallans, Victoria A. Olson, Tessa Moir-Savitz, Nadia F. Gallardo-Romero, R. Mark L. Buller, Erin Touchette, Inger K. Damon, Gopi Patel, Johanna S. Salzer, Catherine M.T. Sherwin, Scott Parker, Pankaj B. Desai, Hari Krishna Ananthula, Daniel Kalman, Milton H. Werner
Publikováno v:
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-11 (2018)
BMC Pharmacology & Toxicology
BMC Pharmacology & Toxicology
Background Several tyrosine kinase inhibitors (TKIs) developed as anti-cancer drugs, also have anti-viral activity due to their ability to disrupt productive replication and dissemination in infected cells. Consequently, such drugs are attractive can
Autor:
R. Mark L. Buller, Nathan L. Ponzar, Juan A. Villa, Lisa Wilson, R. Matt Liley, John E. Sagartz, Elena Lomonosova, Ryan P. Murelli, Kelly R. Long, John E. Tavis, John Bial, Qilan Li, Alexandre Grigoryan, Stephen R. Rapp, Erin Touchette
Chronic hepatitis B virus infection cannot be cured by current therapies, so new treatments are urgently needed. We recently identified novel inhibitors of the hepatitis B virus ribonuclease H that suppress viral replication in cell culture. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b46be5b091682b241b92f80dc87b2c5
https://europepmc.org/articles/PMC5743599/
https://europepmc.org/articles/PMC5743599/
Publikováno v:
Journal of Virology
The proteins encoded by gene 7 of the severe acute respiratory syndrome coronavirus (SARS-CoV) have been demonstrated to have proapoptotic activity when expressed from cDNA but appear to be dispensable for virus replication. Recombinant SARS-CoVs bea
Autor:
Daniel C. Pevear, Guang Yang, Kem Waller, Erik Declercq, Robert O. Baker, Marc H. Davies, Barone Linda, Erin Touchette, Gerry Rhodes, R. L. Mark Buller, Sanjeev Tohan, John W. Huggins, Kevin F. Jones, Dennis E. Hruby, Thomas R. Bailey, Johan Neyts, Robert Jordan, Christopher J. Burns, Marc S. Collett, Jill Schriewer, Susan Rippen
Publikováno v:
Journal of Virology. 79:13139-13149
ST-246 is a low-molecular-weight compound (molecular weight = 376), that is potent (concentration that inhibited virus replication by 50% = 0.010 μM), selective (concentration of compound that inhibited cell viability by 50% = >40 μM), and active a
Autor:
Scott Parker, Alice Robertson, George R. Painter, R. Mark L. Buller, Christina Oberle, Merrick R. Almond, Bernhard Lampert, Erin Touchette, Lawrence C. Trost
Publikováno v:
Antiviral research. 77(1)
In the 21st century we are faced with the potential use of natural or recombinant VARV and MPXV as biological weapons, and the emergence of human MPXV. Such an occurrences would require therapeutic and prophylactic intervention with antivirals. Cidof
Publikováno v:
Antiviral Research. 78:A61-A62
Autor:
Erin Touchette, Stephen Rusbarsky
Publikováno v:
Research and Application of Material. 1:22
Biocontainment Caging systems provide an airtight environment for animals infected with high-risk diseases. In some instances, closed-loop decontamination of these systems is preferable to whole-room decontamination. The goal of this research was to