Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Erin Strydom"'
Supplementary figure 3 from Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic
Autor:
Virna D. Leaner, John O. Trent, Michael J. Birrer, Wei Wei, Dirk Lang, Kate Hadley, Liselotte Angus, Sarah Carden, Erin Strydom, Catherine Stowell, Tamara Stelma, Alicia Chi, Pauline J. van der Watt
Body mass graphs from in vivo studies showing no change in body weight over the treatment time-courses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a0fbe04af14fa266eb8fbe37925cef
https://doi.org/10.1158/1535-7163.22501620.v1
https://doi.org/10.1158/1535-7163.22501620.v1
Autor:
Virna D. Leaner, John O. Trent, Michael J. Birrer, Wei Wei, Dirk Lang, Kate Hadley, Liselotte Angus, Sarah Carden, Erin Strydom, Catherine Stowell, Tamara Stelma, Alicia Chi, Pauline J. van der Watt
IC50 values obtained from INI-43 treatment of cancer, transformed and normal cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5faad515903079a07dbccf8b8423f9b1
https://doi.org/10.1158/1535-7163.22501629.v1
https://doi.org/10.1158/1535-7163.22501629.v1
Autor:
Virna D. Leaner, John O. Trent, Michael J. Birrer, Wei Wei, Dirk Lang, Kate Hadley, Liselotte Angus, Sarah Carden, Erin Strydom, Catherine Stowell, Tamara Stelma, Alicia Chi, Pauline J. van der Watt
Karyopherin beta 1 (Kpnβ1) is a nuclear transport receptor that imports cargoes into the nucleus. Recently, elevated Kpnβ1 expression was found in certain cancers and Kpnβ1 silencing with siRNA was shown to induce cancer cell death. This study aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae6abcb98c5725fed39658f41912007b
https://doi.org/10.1158/1535-7163.c.6536847.v1
https://doi.org/10.1158/1535-7163.c.6536847.v1
Autor:
Virna D. Leaner, John O. Trent, Michael J. Birrer, Wei Wei, Dirk Lang, Kate Hadley, Liselotte Angus, Sarah Carden, Erin Strydom, Catherine Stowell, Tamara Stelma, Alicia Chi, Pauline J. van der Watt
Chemical compounds identified in the in silico screen that display IC50 values of less than 50uM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4005ade69fdf7d2c521b15ee6461b138
https://doi.org/10.1158/1535-7163.22501617
https://doi.org/10.1158/1535-7163.22501617
Supplementary figure 1 from Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic
Autor:
Virna D. Leaner, John O. Trent, Michael J. Birrer, Wei Wei, Dirk Lang, Kate Hadley, Liselotte Angus, Sarah Carden, Erin Strydom, Catherine Stowell, Tamara Stelma, Alicia Chi, Pauline J. van der Watt
Dose-response curves showing cell line responses to INI-43 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a70520e5c0a7430da83031231e3e09d
https://doi.org/10.1158/1535-7163.22501626
https://doi.org/10.1158/1535-7163.22501626
Autor:
Virna D. Leaner, John O. Trent, Michael J. Birrer, Wei Wei, Dirk Lang, Kate Hadley, Liselotte Angus, Sarah Carden, Erin Strydom, Catherine Stowell, Tamara Stelma, Alicia Chi, Pauline J. van der Watt
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd1bf742f9f6aeb25c69030b153f023
https://doi.org/10.1158/1535-7163.22501632.v1
https://doi.org/10.1158/1535-7163.22501632.v1
Autor:
John O. Trent, Alicia Chi, Tamara Stelma, Dirk M. Lang, Michael J. Birrer, Erin Strydom, Virna D. Leaner, Sarah Carden, Pauline J. van der Watt, Wei Wei, Kate Hadley, Catherine L. Stowell, Liselotte Angus
Publikováno v:
Molecular cancer therapeutics. 15(4)
Karyopherin beta 1 (Kpnβ1) is a nuclear transport receptor that imports cargoes into the nucleus. Recently, elevated Kpnβ1 expression was found in certain cancers and Kpnβ1 silencing with siRNA was shown to induce cancer cell death. This study aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6692eed025e81aebaa49019d191e4185
https://pubmed.ncbi.nlm.nih.gov/26832790
https://pubmed.ncbi.nlm.nih.gov/26832790
