Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Erin Shannon"'
Autor:
Tanya E. Keenan, Jennifer L. Guerriero, Romualdo Barroso-Sousa, Tianyu Li, Tess O’Meara, Anita Giobbie-Hurder, Nabihah Tayob, Jiani Hu, Mariano Severgnini, Judith Agudo, Ines Vaz-Luis, Leilani Anderson, Victoria Attaya, Jihye Park, Jake Conway, Meng Xiao He, Brendan Reardon, Erin Shannon, Gerburg Wulf, Laura M. Spring, Rinath Jeselsohn, Ian Krop, Nancy U. Lin, Ann Partridge, Eric P. Winer, Elizabeth A. Mittendorf, David Liu, Eliezer M. Van Allen, Sara M. Tolaney
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
A randomized phase 2 clinical trial has recently shown no benefit of the combination eribulin and pembrolizumab over pembrolizumab alone in HR + metastatic breast cancer patients (NCT03051659). Here, the authors are reporting the final OS data and bi
Externí odkaz:
https://doaj.org/article/d25f24d7eb06482f96ec27595b0111bc
Autor:
David A. Barbie, Raphael Bueno, Cloud P. Paweletz, Rizwan Romee, Michael Y. Tolstorukov, Juan J. Miret, Pasi A. Jänne, Eric L. Smith, Neil Lineberry, Alexander Parent, Richard C. Gregory, Vicky A. Appleman, Adnan O. Abu-Yousif, William G. Richards, Assunta De Rienzo, Marina Vivero, Israel Cañadas, Ze-Hua Li, Pinar O. Eser, Antja-Voy Hartley, Thomas P. Albertson, Timothy J. Haggerty, Kartika Venugopal, Corinne E. Gustafson, Tran C. Thai, Saemi Han, Arrien A. Bertram, Minh Ha, Ha V. Vo, Ari Zlota, Anna M. Lee-Hassett, Pieter J. Schol, Tetsuo Tani, Navin R. Mahadevan, Erin Shannon, Cameron M. Messier, Bonje Obua, Nathaniel Spicer, Brandon Piel, Minyue Chen, Brittany Meisenheimer, Moataz Noureddine, Ismail Ozgenc, Matthew A. Booker, Patrick H. Lizotte, Marco Campisi, Mubin Tarannum, Elena V. Ivanova, Erik H. Knelson
Activation of the stimulator of interferon genes (STING) pathway promotes antitumor immunity but STING agonists have yet to achieve clinical success. Increased understanding of the mechanism of action of STING agonists in human tumors is key to devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34335b05bd2da45a66fc885095d546f7
https://doi.org/10.1158/2326-6066.c.6550907
https://doi.org/10.1158/2326-6066.c.6550907
Autor:
David A. Barbie, Raphael Bueno, Cloud P. Paweletz, Rizwan Romee, Michael Y. Tolstorukov, Juan J. Miret, Pasi A. Jänne, Eric L. Smith, Neil Lineberry, Alexander Parent, Richard C. Gregory, Vicky A. Appleman, Adnan O. Abu-Yousif, William G. Richards, Assunta De Rienzo, Marina Vivero, Israel Cañadas, Ze-Hua Li, Pinar O. Eser, Antja-Voy Hartley, Thomas P. Albertson, Timothy J. Haggerty, Kartika Venugopal, Corinne E. Gustafson, Tran C. Thai, Saemi Han, Arrien A. Bertram, Minh Ha, Ha V. Vo, Ari Zlota, Anna M. Lee-Hassett, Pieter J. Schol, Tetsuo Tani, Navin R. Mahadevan, Erin Shannon, Cameron M. Messier, Bonje Obua, Nathaniel Spicer, Brandon Piel, Minyue Chen, Brittany Meisenheimer, Moataz Noureddine, Ismail Ozgenc, Matthew A. Booker, Patrick H. Lizotte, Marco Campisi, Mubin Tarannum, Elena V. Ivanova, Erik H. Knelson
Supplementary Data from Activation of Tumor-Cell STING Primes NK-Cell Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5f553fda34db80adc5399773dc6ed3
https://doi.org/10.1158/2326-6066.22545320.v1
https://doi.org/10.1158/2326-6066.22545320.v1
Autor:
Sara M. Tolaney, Geoffrey I. Shapiro, Eliezer M. Van Allen, Elizabeth A. Mittendorf, Eric P. Winer, Beth Overmoyer, Alan D'Andrea, Peter K. Sorger, Robert E. Godin, Erin Shannon, Meng X. He, Jake Conway, Leilani Anderson, Rie K. Tahara, Ricardo Pastorello, Janae Davis, Bose Kochupurakkal, Nabihah Tayob, Jennifer L. Guerriero, Tuulia Vallius, Tianyu Li, Tanya E. Keenan
Supplementary Table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6e7627cc9ddf60f5a02e2b2dc2aff9
https://doi.org/10.1158/1078-0432.22478834
https://doi.org/10.1158/1078-0432.22478834
Autor:
Sara M. Tolaney, Geoffrey I. Shapiro, Eliezer M. Van Allen, Elizabeth A. Mittendorf, Eric P. Winer, Beth Overmoyer, Alan D'Andrea, Peter K. Sorger, Robert E. Godin, Erin Shannon, Meng X. He, Jake Conway, Leilani Anderson, Rie K. Tahara, Ricardo Pastorello, Janae Davis, Bose Kochupurakkal, Nabihah Tayob, Jennifer L. Guerriero, Tuulia Vallius, Tianyu Li, Tanya E. Keenan
Supplemental methods, results, figures, tables, and references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22081d2f5cb611bcfbd5caf0bef6ff19
https://doi.org/10.1158/1078-0432.22478837.v1
https://doi.org/10.1158/1078-0432.22478837.v1
Autor:
Sara M. Tolaney, Geoffrey I. Shapiro, Eliezer M. Van Allen, Elizabeth A. Mittendorf, Eric P. Winer, Beth Overmoyer, Alan D'Andrea, Peter K. Sorger, Robert E. Godin, Erin Shannon, Meng X. He, Jake Conway, Leilani Anderson, Rie K. Tahara, Ricardo Pastorello, Janae Davis, Bose Kochupurakkal, Nabihah Tayob, Jennifer L. Guerriero, Tuulia Vallius, Tianyu Li, Tanya E. Keenan
Purpose:We report results from a phase II study assessing the efficacy of the WEE1 inhibitor adavosertib with cisplatin in metastatic triple-negative breast cancer (mTNBC).Patients and Methods:Patients with mTNBC treated with 0–1 prior lines of che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed6d60c813390640a1c4f4d62c02d56
https://doi.org/10.1158/1078-0432.c.6530060
https://doi.org/10.1158/1078-0432.c.6530060
Autor:
Samantha E. Hoffman, Todd W. Dowrey, Carlos Villacorta Martin, Kevin Bi, Breanna Titchen, Shreya Johri, Laura DelloStritto, Miraj Patel, Colin Mackichan, Stephanie Inga, Judy Chen, Grace Grimaldi, Sara Napolitano, Isaac Wakiro, Jingyi Wu, Jason Yeung, Asaf Rotem, Erin Shannon, Thomas Clancy, Jiping Wang, Sarah Denning, Lauren Brais, Ying Huang, Katrina Z. Kao, Scott Rodig, Jason L. Hornick, Sebastien Vigneau, Jihye Park, Matthew H. Kulke, Jennifer Chan, Eliezer M. Van Allen, George J. Murphy
Neuroendocrine tumors (NETs) are rare cancers that may arise in the gastrointestinal tract and pancreas. The fundamental mechanisms driving gastroenteropancreatic (GEP) NET growth remain incompletely elucidated; however, the heterogeneous clinical be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73fedd639cee1edb657fcca70029a49d
https://doi.org/10.1101/2022.11.08.515538
https://doi.org/10.1101/2022.11.08.515538
Autor:
Romualdo Barroso-Sousa, Tanya Keenan, Elizabeth A. Mittendorf, Anita Giobbie-Hurder, Ann H. Partridge, Sara M. Tolaney, Gerburg M. Wulf, Laura Spring, Rinath Jeselsohn, Jake Conway, Brendan Reardon, Tianyu Li, Tess O’Meara, Ian E. Krop, Ines Vaz-Luis, Jihye Park, Erin Shannon, Jiani Hu, Victoria Attaya, Meng Xiao He, Eric P. Winer, Leilani Anderson, Nabihah Tayob, Judith Agudo, Jennifer L. Guerriero, Eliezer M. Van Allen, Nan Lin, Mariano Severgnini, David Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Immune checkpoint inhibitors (ICIs) have minimal therapeutic effect in hormone receptor-positive (HR+ ) breast cancer. We present final overall survival (OS) results (n = 88) from a randomized phase 2 trial of eribulin ± pembrolizumab for patients w
Autor:
Erik H. Knelson, Elena V. Ivanova, Mubin Tarannum, Marco Campisi, Patrick H. Lizotte, Matthew A. Booker, Ismail Ozgenc, Moataz Noureddine, Brittany Meisenheimer, Minyue Chen, Brandon Piel, Nathaniel Spicer, Bonje Obua, Cameron M. Messier, Erin Shannon, Navin R. Mahadevan, Tetsuo Tani, Pieter J. Schol, Anna M. Lee-Hassett, Ari Zlota, Ha V. Vo, Minh Ha, Arrien A. Bertram, Saemi Han, Tran C. Thai, Corinne E. Gustafson, Kartika Venugopal, Timothy J. Haggerty, Thomas P. Albertson, Antja-Voy Hartley, Pinar O. Eser, Ze-Hua Li, Israel Cañadas, Marina Vivero, Assunta De Rienzo, William G. Richards, Adnan O. Abu-Yousif, Vicky A. Appleman, Richard C. Gregory, Alexander Parent, Neil Lineberry, Eric L. Smith, Pasi A. Jänne, Juan J. Miret, Michael Y. Tolstorukov, Rizwan Romee, Cloud P. Paweletz, Raphael Bueno, David A. Barbie
Publikováno v:
Cancer Immunol Res
Activation of the stimulator of interferon genes (STING) pathway promotes antitumor immunity but STING agonists have yet to achieve clinical success. Increased understanding of the mechanism of action of STING agonists in human tumors is key to devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59405d3838890ae4cd6be2b194ac5280
https://europepmc.org/articles/PMC9357206/
https://europepmc.org/articles/PMC9357206/
Autor:
Julia Schiantarelli, Theodora Pappa, Jake Conway, Jett Crowdis, Brendan Reardon, Felix Dietlein, Julian Huang, Darren Stanizzi, Evan Carey, Alice Bosma-Moody, Alma Imamovic, Seunghun Han, Sabrina Camp, Eric Kofman, Erin Shannon, Justine A. Barletta, Meng Xiao He, David Liu, Jihye Park, Jochen H. Lorch, Eliezer M. Van Allen
Publikováno v:
JCO Precision Oncology.
Although papillary thyroid carcinoma (PTC) is the most frequent endocrine tumor with a generally excellent prognosis, a patient developed a clinically aggressive PTC eleven years after receiving platinum chemotherapy for ovarian endometrioid adenocar