Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Erin S. R. Lashinger"'
Publikováno v:
Neurourology and Urodynamics. 28:442-446
Aims We tested cardiovascular and visceromotor reflex (VMR) responses to urinary bladder distension (UBD) in urethane anesthetized rats to see if it can replicate the response pattern and the inhibition of bladder nociceptive transmission by analgesi
Autor:
J. Paul Hieble, Lisa A. Leon, Richard M. Edwards, Jon-Paul Jaworski, Dwight M. Morrow, Charlene W. Wu, Jian Jin, Erin S. R. Lashinger, Nicholas J. Laping, Xin Su
Publikováno v:
American Journal of Physiology-Renal Physiology. 295:F984-F994
Prostaglandin EP3 receptors in the central nervous system (CNS) may exert an excitatory effect on urinary bladder function via modulation of bladder afferent pathways. We have studied this action, using two EP3 antagonists, (2 E)-3-{1-[(2,4-dichlorop
Autor:
Earl Gordon, David P. Brooks, Timothy D. Westfall, Erin S. R. Lashinger, Bartholomew J. Votta, Blake A. Misajet, Linda N. Casillas, Robert W. Marquis, Gerald P. McCafferty, Josephine H.L. Nation, David J. Figueroa, Tim P. Chendrimada, Louise C Evans, Douglas J. DeMarini, Anthony Sulpizio, Zuojun Lin, Angela K. Clouse, Kevin S. Thorneloe, Nicholas J. Laping, Xiaoping Xu, Steven A. Sheardown
Publikováno v:
Scopus-Elsevier
The transient receptor potential (TRP) vanilloid 4 (TRPV4) member of the TRP superfamily has recently been implicated in numerous physiological processes. In this study, we describe a small molecule TRPV4 channel activator, ( N -((1 S )-1-{[4-((2 S )
Publikováno v:
Neurourology and urodynamics. 28(5)
We tested cardiovascular and visceromotor reflex (VMR) responses to urinary bladder distension (UBD) in urethane anesthetized rats to see if it can replicate the response pattern and the inhibition of bladder nociceptive transmission by analgesics se
Autor:
Robert N. Willette, Sandhya S. Nerurkar, Cindy E. Fishman, Gregory H. Turner, Kevin S. Thorneloe, Weike Bao, Gerald Stankus, Robert W. Marquis, Tian-Li Yue, David J. Figueroa, David J. Behm, Robert E. Lee Trout, Bartholomew J. Votta, Xiaoping Xu, Anthony Sulpizio, Erin S. R. Lashinger, Heath Thomas, Chris P. Doe, Linda N. Casillas, Zuojun Lin, Irina M. Lozinskaya, Sandra J. Hoffman, Haisong Ju, Min Lin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 326(2)
The transient receptor potential (TRP) vanilloid subtype 4 (V4) is a nonselective cation channel that exhibits polymodal activation and is expressed in the endothelium, where it contributes to intracellular Ca2+ homeostasis and regulation of cell vol