Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Erin S Honsa"'
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104794 (2014)
Iron is essential for bacterial survival, being required for numerous biological processes. NEAr-iron Transporter (NEAT) domains have been studied in pathogenic Gram-positive bacteria to understand how their proteins obtain heme as an iron source dur
Externí odkaz:
https://doaj.org/article/d54d28d7e25444a8bf9e6df26a140fa2
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 3 (2013)
For bacterial pathogens whose sole environmental reservoir is the human host, the acquisition of essential nutrients, particularly transition metals, is a critical aspect of survival due to tight sequestration and limitation strategies deployed to cu
Externí odkaz:
https://doaj.org/article/aaa43d900e634894aee61624261c20fd
Autor:
MarCia T Ekworomadu, Catherine B Poor, Cedric P Owens, Miriam A Balderas, Marian Fabian, John S Olson, Frank Murphy, Erol Bakkalbasi, Erin S Honsa, Chuan He, Celia W Goulding, Anthony W Maresso
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002559 (2012)
To replicate in mammalian hosts, bacterial pathogens must acquire iron. The majority of iron is coordinated to the protoporphyrin ring of heme, which is further bound to hemoglobin. Pathogenic bacteria utilize secreted hemophores to acquire heme from
Externí odkaz:
https://doaj.org/article/56c677eeda1c4146833e8d2069b9ff28
Autor:
Roxana Nouri-Nikbakht, Erin S. Honsa
Publikováno v:
Reviews in Medical Microbiology. 33:65-73
Autor:
Stephanie L. Neville, Hannah M. Rowe, Amy R. Iverson, Christopher A. McDevitt, Christopher Deitrick, Vaughn S. Cooper, Colin C. Kietzman, Erin S. Honsa, Jason W. Rosch, Jonathan J. Whittall
Publikováno v:
mSystems, Vol 5, Iss 3 (2020)
mSystems, Vol 5, Iss 3, p e00352-20 (2020)
mSystems, Vol 5, Iss 3, p e00352-20 (2020)
Experimental evolution is a powerful technique to understand how populations evolve from selective pressures imparted by the surrounding environment. With the advancement of whole-population genomic sequencing it is possible to identify and track mul
Autor:
Lindsey R, Brown, Rachel C, Caulkins, Tyler E, Schartel, Jason W, Rosch, Erin S, Honsa, Stacey, Schultz-Cherry, Victoria A, Meliopoulos, Sean, Cherry, Justin A, Thornton
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Bacteria growing within biofilms are protected from antibiotics and the immune system. Within these structures, horizontal transfer of genes encoding virulence factors, and promoting antibiotic resistance occurs, making biofilms an extremely importan
RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host
Autor:
Erin S. Honsa, Vaughn S. Cooper, Mohammed N. Mhaissen, Matthew Frank, Jessica Shaker, Amy Iverson, Jeffrey Rubnitz, Randall T. Hayden, Richard E. Lee, Charles O. Rock, Elaine I. Tuomanen, Joshua Wolf, Jason W. Rosch, Michael S. Gilmore
Publikováno v:
mBio, Vol 8, Iss 1, p e02124-16 (2017)
mBio
mBio, Vol 8, Iss 1 (2017)
mBio
mBio, Vol 8, Iss 1 (2017)
Serious bacterial infections in immunocompromised patients require highly effective antibacterial therapy for cure, and thus, this setting may reveal novel mechanisms by which bacteria circumvent antibiotics in the absence of immune pressure. Here, a
Publikováno v:
Journal of Biological Chemistry. 288:8479-8490
Several gram-positive pathogenic bacteria employ near-iron transporter (NEAT) domains to acquire heme from hemoglobin during infection. However, the structural requirements and mechanism of action for NEAT-mediated heme extraction remains unknown. Ba
Publikováno v:
Journal of Biological Chemistry. 286:33652-33660
Pathogenic bacteria require iron to replicate inside mammalian hosts. Recent studies indicate that heme acquisition in Gram-positive bacteria is mediated by proteins containing one or more near-iron transporter (NEAT) domains. Bacillus anthracis is a
Autor:
Anthony W. Maresso, Christopher L. Nobles, Embriette R. Alicki, Erin S. Honsa, Miriam Balderas
The metal iron is a limiting nutrient for bacteria during infection. Bacillus anthracis , the causative agent of anthrax and a potential weapon of bioterrorism, grows rapidly in mammalian hosts, which suggests that it efficiently attains iron during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6e6a2969f144835c411f66a743a2c2
https://europepmc.org/articles/PMC3458686/
https://europepmc.org/articles/PMC3458686/