Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Erin R. Hascup"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Microglia are the resident macrophages of the central nervous system (CNS) that control brain development, maintain neural environments, respond to injuries, and regulate neuroinflammation. Despite their significant impact on various physiological an
Externí odkaz:
https://doaj.org/article/4d579cd2e5d24e57a7d4ed0e04e04d42
Autor:
Justin T. McDaniel, Kevin N. Hascup, Erin R. Hascup, Ugochukwu G. Ezigbo, Amanda M. Weidhuner, Harvey Henson, David L. Albright
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/0da7138d30ff4c9d9c3bd2506831f169
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Since brain glucose hypometabolism is a feature of Alzheimer’s disease (AD) progression, lactate utilization as an energy source may become critical to maintaining central bioenergetics. We have previously shown that soluble amyloid-β (A
Externí odkaz:
https://doaj.org/article/6e3d3ea3aa544caa8f35dc07e9bce523
Autor:
Caleigh A. Findley, MaKayla F. Cox, Adam B. Lipson, RaTasha Bradley, Kevin N. Hascup, Carla Yuede, Erin R. Hascup
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
In the United States, 80% of surveyed Black patients report experiencing barriers to healthcare for Alzheimer’s disease and related dementias (ADRD), delaying the time-sensitive treatment of a progressive neurodegenerative disease. According to the
Externí odkaz:
https://doaj.org/article/af2df94da4994b76b4023a6a71c3c9fd
Autor:
Madison G. Hollinshead BA, Albert Botchway PhD, Kathleen E. Schmidt PhD, Gabriella L. Weybright BA, Ronald F. Zec PhD, Thomas A. Ala MD, Stephanie R. Kohlrus BA, M. Rebecca Hoffman MD, MSPH, Amber S. Fifer PharmD, Erin R. Hascup PhD, Mehul A. Trivedi PhD
Publikováno v:
Gerontology and Geriatric Medicine, Vol 8 (2022)
We used principal component analysis (PCA) to examine the component structure of a neuropsychological test battery administered to 943 cognitively-normal adults enrolled in the Southern Illinois University (SIU) Longitudinal Cognitive Aging Study (LC
Externí odkaz:
https://doaj.org/article/c8536bc323984f6e928c36231b92b43d
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Aging is a naturally occurring decline of physiological processes and biological pathways that affects both the structural and functional integrity of the body and brain. These physiological changes reduce motor skills, executive function, memory rec
Externí odkaz:
https://doaj.org/article/d0fe4f9c6e41456a927503cd971b0b21
Autor:
Justin T. McDaniel PhD, Erin R. Hascup PhD, Kevin N. Hascup PhD, Mehul Trivedi PhD, Harvey Henson PhD, Robert Rados PhD, Mary York MSW, David L. Albright PhD, Taryn Weatherly BS, Kaitlyn Frick BS
Publikováno v:
Gerontology and Geriatric Medicine, Vol 8 (2022)
The purpose of this study was to explore the association between psychological resilience and cognitive function in military veterans. We obtained public-use data from the Health and Retirement Study (HRS) for this cross-sectional study of military v
Externí odkaz:
https://doaj.org/article/c571a488350b49cc94be8441fa0bfae7
Autor:
Erin R. Hascup, Kevin N. Hascup
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Alzheimer's disease (AD) is an age‐related neurodegenerative disorder characterized by progressive anterograde amnesia, cerebral atrophy, and eventual death. Current treatment has limited efficacy and cannot decelerate the disease progress
Externí odkaz:
https://doaj.org/article/e785543690254dfb84ff9b6f25195e38
Publikováno v:
ASN Neuro, Vol 11 (2019)
Alzheimer’s disease (AD) ranks sixth on the Centers for Disease Control and Prevention Top 10 Leading Causes of Death list for 2016, and the Alzheimer’s Association attributes 60% to 80% of dementia cases as AD related. AD pathology hallmarks inc
Externí odkaz:
https://doaj.org/article/5452d97c7b224d0a8692baf5151e5a31
Autor:
Caleigh A. Findley, Samuel A. McFadden, MaKayla F. Cox, Lindsey N. Sime, Mackenzie R. Peck, Kathleen Quinn, Andrzej Bartke, Kevin N. Hascup, Erin R. Hascup
Publikováno v:
Journal of Alzheimer's Disease. :1-22
Background: Prior research supports a strong link between Alzheimer’s disease (AD) and metabolic dysfunction that involves a multi-directional interaction between glucose, glutamatergic homeostasis, and amyloid pathology. Elevated soluble amyloid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c61aa013b7b9348a100e9a234205863
https://doi.org/10.3233/jad-221245
https://doi.org/10.3233/jad-221245