Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Erin Prendergast"'
Autor:
Theodore L. Mathuram, Danyelle M. Townsend, Vincent J. Lynch, Ilya Bederman, Zhi-Wei Ye, Jie Zhang, Wade J. Sigurdson, Erin Prendergast, Raul Jobava, Jonathan P. Ferruzza, Mary R. D’Angelo, Maria Hatzoglou, Yaron Perry, Anna Blumental-Perry
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Mitochondrial malfunction is a hallmark of many diseases, including neurodegenerative disorders, cardiovascular and lung diseases, and cancers. We previously found that alveolar progenitor cells, which are more resistant to cigarette smoke-induced in
Externí odkaz:
https://doaj.org/article/f5dff9159b59448badb5f7f4173eea60
Autor:
Ali Vaziri-Gohar, Joel Cassel, Farheen S. Mohammed, Mehrdad Zarei, Jonathan J. Hue, Omid Hajihassani, Hallie J. Graor, Yellamelli V. V. Srikanth, Saadia A. Karim, Ata Abbas, Erin Prendergast, Vanessa Chen, Erryk S. Katayama, Katerina Dukleska, Imran Khokhar, Anthony Andren, Li Zhang, Chunying Wu, Bernadette Erokwu, Chris A. Flask, Mahsa Zarei, Rui Wang, Luke D. Rothermel, Andrea M. P. Romani, Jessica Bowers, Robert Getts, Curtis Tatsuoka, Jennifer P. Morton, Ilya Bederman, Henri Brunengraber, Costas A. Lyssiotis, Joseph M. Salvino, Jonathan R. Brody, Jordan M. Winter
Publikováno v:
Nature Cancer. 3:852-865
Nutrient-deprived conditions in the tumor microenvironment (TME) restrain cancer cell viability due to increased free radicals and reduced energy production. In pancreatic cancer cells a cytosolic metabolic enzyme, wild-type isocitrate dehydrogenase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3094737c279b470283468552b409050b
https://doi.org/10.1038/s43018-022-00393-y
https://doi.org/10.1038/s43018-022-00393-y
Publikováno v:
Neurotherapeutics
Cholesterol and 24-hydroxycholesterol are the most abundant brain sterols and represent the substrate and product, respectively, of cytochrome P450 46A1 (CYP46A1), a CNS-specific enzyme. CYP46A1 controls cholesterol elimination and turnover in the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d30f2e5e9e76eb35f03bd169ed99e0
https://doi.org/10.1007/s13311-021-01079-6
https://doi.org/10.1007/s13311-021-01079-6
Autor:
Irina A. Pikuleva, Erin Prendergast, Tung Dao, Aicha Saadane, Ilya Bederman, Emmy Schwarz, Artem A. Astafev, Alexey M. Petrov, Natalia Mast, Nicole El-Darzi
Publikováno v:
Cellular and Molecular Life Sciences. 78:963-983
Apolipoprotein D (APOD) is an atypical apolipoprotein with unknown significance for retinal structure and function. Conversely, apolipoprotein E (APOE) is a typical apolipoprotein with established roles in retinal cholesterol transport. Herein, we im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851001f9fc8c530ae10a22d5e0150609
https://doi.org/10.1007/s00018-020-03546-3
https://doi.org/10.1007/s00018-020-03546-3
Autor:
Alberto C S Costa, Ana C Brandão, Richard Boada, Veridiana L Barrionuevo, Hudson G Taylor, Elizabeth Roth, Melissa R Stasko, Mark W Johnson, Fernanda F Assir, Maria P Roberto, Patrícia Salmona, Guilherme Abreu-Silveira, Ilya Bederman, Erin Prendergast, Anke Hüls, Sarina Abrishamcar, Zan Mustacchi, Thomas Scheidemantel, Nancy J Roizen, Stephen Ruedrich
Publikováno v:
The Lancet. Neurology. 21(1)
Down syndrome is a chromosomal disorder with considerable neurodevelopmental impact and neurodegenerative morbidity. In a pilot trial in young adults with Down syndrome, memantine (a drug approved for Alzheimer's disease) showed a significant effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce8a0a56644af1018a59602273a046c
https://pubmed.ncbi.nlm.nih.gov/34942129
https://pubmed.ncbi.nlm.nih.gov/34942129
Autor:
Nicole, El-Darzi, Natalia, Mast, Alexey M, Petrov, Tung, Dao, Artem A, Astafev, Aicha, Saadane, Erin, Prendergast, Emmy, Schwarz, Ilya, Bederman, Irina A, Pikuleva
Publikováno v:
Cell Mol Life Sci
Apolipoprotein D (APOD) is an atypical apolipoprotein with unknown significance for retinal structure and function. Conversely, apolipoprotein E (APOE) is a typical apolipoprotein with established roles in retinal cholesterol transport. Herein, we im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22590872c82c88aa13add558b2e39848
https://pubmed.ncbi.nlm.nih.gov/32440710
https://pubmed.ncbi.nlm.nih.gov/32440710
Autor:
Erin Prendergast, Leah Broadhurst, Amy Geller, Kalpana Parvatheaneni, Holly Berkley, Asad Moten, Brandon Shumway, Chandani Desai, Morgan Harvey, Samuel McAleese, Kristin Wertin, Emilie Biondokin, Uneeb Qureshi, Neil Shelat, Caitlin Ingraham, Courtney Middlebrook, William Patrick Luan, Carrie Gillispie, Viraj Bhatt, Sara Mullery, Nathan Praschan, Cameron Clarke, Adria Peterkin, Jolynn Gardner, Hannah Risheq, Sarah Baden, Ayramana Correa, Mamta Chaudhari, Sophie Yang, Demi Lewis, Sandy Fulkerson Schaeffer, Atila Libutsi
Publikováno v:
NAM Perspectives. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05a671a49d7a2b6a21cb73be1cb89f0
https://doi.org/10.31478/201510a
https://doi.org/10.31478/201510a