Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Erin P. Sproul"'
Autor:
Jennifer L Sollinger, Andrew Bond, Eunice Chee, Douglas B. Snider, Kimberly Nellenbach, Glenn Cruse, Seema Nandi, Erin P. Sproul, Maureane Hoffman, Ashley C. Brown, Landon Morrill, Emily Mihalko
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 108:2599-2609
Platelets crucially facilitate wound healing but can become depleted in traumatic injury or chronic wounds. Previously, our group developed injectable platelet-like particles (PLPs) comprised of highly deformable, ultralow crosslinked pNIPAm microgel
Autor:
Mary Erb, Donald O. Freytes, Ashley C. Brown, Erin P. Sproul, Seema Nandi, Lewis Gaffney, Kimberly Nellenbach
Publikováno v:
Biomaterials Science. 7:669-682
Native platelets perform several critical functions within the context of wound healing, including participating in initial hemostasis and interacting with fibrin at the wound site to induce clot retraction. Platelet depletion or dysfunction due to t
Autor:
Ashley C. Brown, Supriya Sivadanam, Benjamin J. Igo, Eunice Chee, Erin P. Sproul, Seema Nandi, Luisa Schreck
Publikováno v:
Regen Eng Transl Med
A blood clot is formed in response to bleeding by platelet aggregation and adherence to fibrin fibers. Platelets contract over time, stabilizing the clot, which contributes to wound healing. We have developed platelet-like particles (PLPs) that augme
Publikováno v:
ACS Nano. 12:7826-7837
Myocardial infarction (MI), commonly known as a heart attack, affects millions of people worldwide and results in significant death and disabilities. A major cause of MI is fibrin-rich thrombus formation that occludes the coronary arteries, blocking
Autor:
Jhon Cores, Zegen Wang, Leonard J. Lobo, Jinying Zhang, Michael Taylor Hensley, Laura Ruterbories, Phuong-Uyen Dinh, Erin P. Sproul, Ke Cheng, Tao-Sheng Li, Tyler A. Allen, Adam C. Vandergriff, Junnan Tang, Zhen Gu, Alex M. Lynch, Ke Huang, George A. Stouffer, Deliang Shen, Thomas G. Caranasos, Ashley C. Brown, Teng Su, Emily Mihalko
Publikováno v:
Nature Biomedical Engineering. 2:17-26
Stem cell transplantation, as used clinically, suffers from low retention and engraftment of the transplanted cells. Inspired by the ability of platelets to recruit stem cells to sites of injury on blood vessels, we hypothesized that platelets might
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1758
Fibrin is an integral part of the clotting cascade and is formed by polymerization of the soluble plasma protein fibrinogen. Following stimulation of the coagulation cascade, thrombin activates fibrinogen, which binds to adjacent fibrin(ogen) molecul
Autor:
W. Scott Argraves, Erin P. Sproul
Publikováno v:
Matrix Biology. 32(2):86-94
Underlying the dynamic regulation of tropoelastin expression and elastin formation in development and disease are transcriptional and post-transcriptional mechanisms that have been the focus of much research. Of particular importance is the cytokine-
Publikováno v:
Adv Biosyst
Platelets mediate hemostasis by aggregating and binding to fibrin to promote clotting. Over time, platelets contract the fibrin network to induce clot retraction, which contributes to wound healing outcomes by increasing clot stability and improving
Autor:
Thomas N. Wight, Jeremy L. Barth, Erin P. Sproul, Gail Workman, Kathleen R. Braun, W. Scott Argraves, Dong Won Yoon, Inkyung Kang
Publikováno v:
The Journal of biological chemistry. 290(35)
Arterial smooth muscle cells (ASMCs) undergo phenotypic changes during development and pathological processes in vivo and during cell culture in vitro. Our previous studies demonstrated that retrovirally mediated expression of the versican V3 splice