Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Erin Nevius"'
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Akademický článek
Selective deletion of the receptor for CSF1, c-fms, in osteoclasts results in a high bone mass phenotype, smaller osteoclasts in vivo and an impaired response to an anabolic PTH regimen.
Autor: Meiling Zhu, Ben-Hua Sun, Erin Nevius, Jared Kaplan, João Pereira, Karl Insogna
Publikováno v: PLoS ONE, Vol 16, Iss 2, p e0247199 (2021)
The receptor for Colony Stimulating Factor 1 (CSF1), c-fms, is highly expressed on mature osteoclasts suggesting a role for this cytokine in regulating the function of these cells. Consistent with this idea, in vitro studies have documented a variety
Externí odkaz: https://doaj.org/article/503f51ff71914ba193a0af5a5831eab3
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2
Hematopoietic Stem Cell Niches Produce Lineage-Instructive Signals to Control Multipotent Progenitor Differentiation
Autor: Vivian Y. Lim, Koichi Ikuta, João Pereira, Dietmar Herndler-Brandstetter, Erin Nevius, Ellen R. Richie, Richard A. Flavell, Hans Reimer Rodewald, Tatsuki Sugiyama, Takashi Nagasawa, Shizue Tani-ichi, Takahiro Hara, Ana Cordeiro Gomes, Susan M. Schlenner
Publikováno v: Immunity. 45:1219-1231
Hematopoietic stem cells (HSCs) self-renew in bone marrow niches formed by mesenchymal progenitors and endothelial cells expressing the chemokine CXCL12, but whether a separate niche instructs multipotent progenitor (MPP) differentiation remains uncl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa67a49a6416b204f9cdcc4ada9ff09a
https://doi.org/10.1016/j.immuni.2016.11.004
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4
Selective deletion of the receptor for CSF1, c-fms, in osteoclasts results in a high bone mass phenotype, smaller osteoclasts in vivo and an impaired response to an anabolic PTH regimen
Autor: Ben-hua Sun, Erin Nevius, João Pereira, Jared Kaplan, Meiling Zhu, Karl L. Insogna
Publikováno v: PLoS ONE, Vol 16, Iss 2, p e0247199 (2021)
PLoS ONE
The receptor for Colony Stimulating Factor 1 (CSF1), c-fms, is highly expressed on mature osteoclasts suggesting a role for this cytokine in regulating the function of these cells. Consistent with this idea, in vitro studies have documented a variety
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d319b2e77f31a0fdb7c688ed00578397
https://doi.org/10.1371/journal.pone.0247199
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5
Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo
Autor: Ben-hua Sun, João Pereira, Katarzyna Saar, Meiling Zhu, LeAnn M. Tiede-Lewis, Robert S. Weinstein, Nancy Troiano, Sarah L. Dallas, Erin Nevius, Steven M. Tommasini, Karl L. Insogna, Christine A. Simpson
Publikováno v: Journal of Bone and Mineral Research. 31:864-873
Rac1 and Rac2 are thought to have important roles in osteoclasts. Therefore, mice with deletion of both Rac1 and Rac2 in mature osteoclasts (DKO) were generated by crossing Rac1(flox/flox) mice with mice expressing Cre in the cathepsin K locus and th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0e04094870baee677ffba462f8f4646
https://doi.org/10.1002/jbmr.2733
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6
Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review
Autor: João Pereira, Erin Nevius, Ana Cordeiro Gomes
Publikováno v: Clinical Reviews in Allergy & Immunology. 51:59-78
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affects the joints. Self-reactive B and T lymphocytes cooperate to promote antibody responses against self proteins and are major drivers of disease. T lymphocytes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af01dc8da710a88837aec4507093270f
https://doi.org/10.1007/s12016-015-8520-9
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8
Trafficking of Osteoclast Precursors
Autor: João Pereira, Masaru Ishii, Erin Nevius, Junichi Kikuta
Osteoclast precursors are thought to follow chemotactic cues within the bone marrow in order to be properly positioned at bone surfaces where osteoblasts reside, and possibly where osteocyte cell processes are exposed. Osteoclast precursor positionin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b3f94afb734c0acfe8309e1c45e9abd
https://doi.org/10.1016/b978-0-12-800571-2.00003-7
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9
Oral ingestion of Capsaicin, the pungent component of chili pepper, enhances a discreet population of macrophages and confers protection from autoimmune diabetes
Autor: Erin Nevius, Pramod K. Srivastava, Sreyashi Basu
Publikováno v: Mucosal Immunology. 5:76-86
Vanilloid receptor 1 (VR1) is expressed on immune cells as well as on sensory neurons. Here we report that VR1 can regulate immunological events in the gut in response to its ligand Capsaicin (CP), a nutritional factor, the pungent component of chili
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101b7861ba63aa8beaaa03b0cedb2d72
https://doi.org/10.1038/mi.2011.50
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10
Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis
Autor: Mark C. Horowitz, Meera Dhodapkar, Masaru Ishii, Junichi Kikuta, Flavia Pinho, João Pereira, Kristina Nadrah, Erin Nevius, Huiyan Jin
Publikováno v: The Journal of Experimental Medicine
The mechanisms guiding cells toward bone surfaces are generally unknown. Here, Nevius et al. show that the Gαi protein–coupled receptor EBI2 is expressed in mouse osteoclast precursors to guide these cells toward bone surfaces. Defective EBI2 sign
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac96a442e67b0bdaaa2f81fa9c2e1b71
https://pubmed.ncbi.nlm.nih.gov/26438360
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