Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Erin N. Potts"'
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27137 (2011)
Ozone exposure is associated with exacerbation of reactive airways disease. We have previously reported that the damage-associated molecular pattern, hyaluronan, is required for the complete biological response to ambient ozone and that hyaluronan fr
Externí odkaz:
https://doaj.org/article/545aa47d54c74b10aad7a7c775c3541f
Autor:
Richard L. Auten, Chang Won Choi, Mulugu V. Brahmajothi, Beyong Il Kim, Erin N. Potts-Kant, Stanley N. Mason
Publikováno v:
Pediatric Research
Background: We previously showed that intra-amniotic lipopolysaccharide (LPS) amplifies alveolar hypoplasia induced by postnatal hyperoxia. We determined whether the priming effect of intra-amniotic LPS amplifies hyperoxia-induced airway hyperreactiv
Autor:
Benjamin W. Frush, James Y. Lindsey, John W. Hollingsworth, Erin N. Potts-Kant, Robert M. Tighe, W. Michael Foster, Zhuowei Li
Publikováno v:
Free radical biologymedicine. 113
Emphysema is currently a leading cause of mortality with no known effective therapy to attenuate progressive loss of lung function. Previous work support that activation of nuclear factor erythroid 2-related factor 2 (Nrf2) is protective to the lung
Autor:
W. Michael Foster, Kristina J. Riebe, Christopher P. Shelburne, Cong Jin, Guojie Li, Gregory D. Sempowski, Erin N. Potts, Soman N. Abraham
Allergic asthma is characterized by airway hyperresponsiveness, inflammation, and a cellular infiltrate dominated by eosinophils. Numerous epidemiological studies have related the exacerbation of allergic asthma with an increase in ambient inhalable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b816c99c0614d230aa0f4d39dbef95
https://europepmc.org/articles/PMC5617660/
https://europepmc.org/articles/PMC5617660/
Autor:
Erin N. Potts-Kant, Apparao B. Kummarapurugu, Andrew J. Ghio, Bernard M. Fischer, Laura G. Dubois, Shuo Zheng, Erik J. Soderblom, M. Arthur Moseley, Ginger L. Milne, J. Will Thompson, Judith A. Voynow, W. Michael Foster
Publikováno v:
Journal of Biological Chemistry. 288:4681-4691
NADPH quinone oxidoreductase 1 (NQO1) is recognized as a major susceptibility gene for ozone-induced pulmonary toxicity. In the absence of NQO1 as can occur by genetic mutation, the human airway is protected from harmful effects of ozone. We recently
Autor:
Yiming Wu, Feifei Feng, Zhuowei Li, John W. Hollingsworth, W. Michael Foster, Erin N. Potts-Kant, Kristi L. Williams
Publikováno v:
Environmental Health Perspectives
Background: The role of the Nlrp3 inflammasome in nonallergic airway hyperresponsiveness (AHR) has not previously been reported. Recent evidence supports both interleukin (IL) 1β and short fragments of hyaluronan (HA) as contributors to the biologic
Autor:
Gregory S. Whitehead, Stavros Garantziotis, Shuichiro Maruoka, John K. Tomfohr, Erin N. Potts, John W. Hollingsworth, Nathaniel W. Bailey, David M. Brass, Kathy Boon, David A. Schwartz, Zhuowei Li
Asthma is a complex heritable disease that is increasing in prevalence and severity, particularly in developed countries such as the United States, where 11% of the population is affected. The contribution of environmental and genetic factors to this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b22959689edc8defb31ec20f13261ee
https://europepmc.org/articles/PMC4855943/
https://europepmc.org/articles/PMC4855943/
Autor:
Sarah Frush, Zhuowei Li, Erin N. Potts, Wanglei Du, Jerry P. Eu, Stavros Garantziotis, You-Wen He, W. Michael Foster, John W. Hollingsworth
Publikováno v:
Environmental Health Perspectives. 124
Autor:
John W. Hollingsworth, Monica Kraft, Druhan L. Howell, Sin-Ho Jung, Jennifer L. Ingram, Tony D. Church, Erin N. Potts-Kant, Ying Wang, Njira L Lugogo, Loretta G. Que, Dave Francisco
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 186:404-411
Rationale: Obesity is associated with increased prevalence and severity of asthma. Adipose tissue macrophages can contribute to the systemic proinflammatory state associated with obesity. However, it remains unknown whether alveolar macrophages have
Autor:
John Nouls, Bastiaan Driehuys, S. Sivaram Kaushik, Abraham C. Thomas, Erin N. Potts, Deborah Slipetz, W. Michael Foster
Publikováno v:
Journal of Applied Physiology. 112:1437-1444
The purpose of this study was to assess the effects of corticosteroid therapy on a murine model of allergic asthma using hyperpolarized 3He magnetic resonance imaging (MRI) and respiratory mechanics measurements before, during, and after methacholine