Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Erin N. Dankert"'
Autor:
Sk. Kayum Alam, Matteo Astone, Ping Liu, Stephanie R. Hall, Abbygail M. Coyle, Erin N. Dankert, Dane K. Hoffman, Wei Zhang, Rui Kuang, Anja C. Roden, Aaron S. Mansfield, Luke H. Hoeppner
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-15 (2018)
Sk. Kayum Alam et al. show that DARPP-32 isoforms, mediators of dopamine signaling, promote lung tumor growth through non-canonical NF-κB signaling. This study suggests a possibility of using DARPP-32 isoforms as a prognostic marker for lung cancer.
Externí odkaz:
https://doaj.org/article/38a7c18c54fe45189102b95eae61c393
Autor:
Shizhen Zhu, John M. Maris, Jennifer J. Westendorf, Hu Li, Jan M. van Deursen, A. Thomas Look, S. John Weroha, Komal S. Rathi, Gina L. Razidlo, Alexander Meves, Julia S. Lehman, Jorge Torres-Mora, Karen Fritchie, Ting Tao, Shuning He, Shuai Li, Janine H. van Ree, Xiaonan Hou, Cassie J. Howe, Zuag Paj Her, Taylor M. Levee, Choong Yong Ung, Jo Lynne Rokita, Erin N. Dankert Eggum, Cheng Zhang, Gonzalo Lopez, Kok Siong Yeo, Zhiwei Dong
SUPPLEMENTARY TABLES, FIGURES AND FIGURE LEGENDS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438549837a6a26ad2aa79d8ab5c9d0bb
https://doi.org/10.1158/0008-5472.22429665
https://doi.org/10.1158/0008-5472.22429665
Autor:
Shizhen Zhu, John M. Maris, Jennifer J. Westendorf, Hu Li, Jan M. van Deursen, A. Thomas Look, S. John Weroha, Komal S. Rathi, Gina L. Razidlo, Alexander Meves, Julia S. Lehman, Jorge Torres-Mora, Karen Fritchie, Ting Tao, Shuning He, Shuai Li, Janine H. van Ree, Xiaonan Hou, Cassie J. Howe, Zuag Paj Her, Taylor M. Levee, Choong Yong Ung, Jo Lynne Rokita, Erin N. Dankert Eggum, Cheng Zhang, Gonzalo Lopez, Kok Siong Yeo, Zhiwei Dong
One of the greatest barriers to curative treatment of neuroblastoma is its frequent metastatic outgrowth prior to diagnosis, especially in cases driven by amplification of the MYCN oncogene. However, only a limited number of regulatory proteins that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3daaf20c598ffebd4594a52ff7e6e62
https://doi.org/10.1158/0008-5472.c.6513432.v1
https://doi.org/10.1158/0008-5472.c.6513432.v1
Autor:
Hu Li, Cheng Zhang, Gina L. Razidlo, Shuning He, Xiaonan Hou, Jo Lynne Rokita, Choong Yong Ung, Zhi-Wei Dong, Cassie J. Howe, Taylor M. Levee, S. John Weroha, Zuag Paj Her, Jennifer J. Westendorf, Janine H. van Ree, Julia S. Lehman, Kok Siong Yeo, John M. Maris, Alexander Meves, Erin N. Dankert Eggum, Shuai Li, Gonzalo Lopez, Shizhen Zhu, Jan M. van Deursen, Ting Tao, Jorge Torres-Mora, A. Thomas Look, Komal S. Rathi, Karen J. Fritchie
Publikováno v:
Cancer Research. 81:2995-3007
One of the greatest barriers to curative treatment of neuroblastoma is its frequent metastatic outgrowth prior to diagnosis, especially in cases driven by amplification of the MYCN oncogene. However, only a limited number of regulatory proteins that
Akademický článek
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Autor:
Anja C. Roden, Sk Kayum Alam, Rui Kuang, Matteo Astone, Aaron S. Mansfield, Abbygail M. Coyle, Stephanie R. Hall, Ping Liu, Erin N. Dankert, Dane K. Hoffman, Wei Zhang, Luke H. Hoeppner
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-15 (2018)
Lung cancer is the leading cause of cancer-related death worldwide. Here we demonstrate that elevated expression of dopamine and cyclic adenosine monophosphate-regulated phosphoprotein, Mr 32000 (DARPP-32), and its truncated splice variant t-DARPP pr
Autor:
Anja C. Roden, Dane K. Hoffman, Hall, Luke H. Hoeppner, Abbygail M. Coyle, Aaron S. Mansfield, Sk Kayum Alam, Rui Kuang, Matteo Astone, Wei Zhang, Ping Liu, Erin N. Dankert
Lung cancer is the leading cause of cancer-related death worldwide. In this study, we demonstrate that elevated expression of dopamine and cyclic adenosine monophosphate-regulated phosphoprotein, Mr 32000 (DARPP-32) and its truncated splice variant t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d8a3beca0b2b4ed67a8f20b2dac2a7
https://doi.org/10.1101/229658
https://doi.org/10.1101/229658
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 1, Iss 1, Pp 1-14 (2017)
npj Precision Oncology, Vol 1, Iss 1, Pp 1-14 (2017)
Zebrafish have proven to be a valuable model to study human cancer biology with the ultimate aim of developing new therapies. Danio rerio are amenable to in vivo imaging, high-throughput drug screening, mutagenesis, and transgenesis, and they share h
Autor:
Abbygail M. Coyle, Dane K. Hoffman, Matteo Astone, Aaron S. Mansfield, SK Kayum Alam, Wei Zhang, Stephanie R. Hall, Rui Kuang, Ping Liu, Anja C. Roden, Li Wang, Luke H. Hoeppner, Erin N. Dankert
Publikováno v:
Cancer Research. 79:873-873
Lung cancer is the deadliest and most frequently diagnosed type of tumor worldwide, with 1.6 million deaths reported annually. Non-small cell lung cancer (NSCLC) represents 85% of all lung cancer cases and carries a poor 5-year survival rate below 15
Autor:
Zhiwei Dong, Gonzalo Lepez Garcia, Cheng Zhang, Erin N. Dankert, Jo Lynne Harenza, Xiaonan Hou, Hu Li, John M. Maris, Shizhen (Jane) Zhu
Publikováno v:
Cancer Research. 79:LB-127
Neuroblastoma is an embryonal tumor arising in the peripheral sympathetic nervous system (PSNS), and often presents with widespread metastasis at diagnosis. We recently demonstrated that overexpression of LMO1 can synergize with MYCN to promote tumor