Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Erin N Shirk"'
Autor:
Natalie J. Castell, Celina M. Abreu, Erin N. Shirk, Suzanne E. Queen, Joseph L. Mankowski, Janice E. Clements, Rebecca T. Veenhuis
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114833- (2024)
Summary: Viral encephalitis is a growing public health threat with limited diagnostic and treatment options. Simian immunodeficiency virus (SIV)-infected macaques are an established model for human immunodeficiency virus (HIV), and approximately 60%
Externí odkaz:
https://doaj.org/article/af5a772730034531ac835234f852a782
Autor:
Celina M Abreu, Sarah L Price, Erin N Shirk, Rodrigo D Cunha, Luiz F Pianowski, Janice E Clements, Amilcar Tanuri, Lucio Gama
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97257 (2014)
HIV infection is not cleared by antiretroviral drugs due to the presence of latently infected cells that are not eliminated with current therapies and persist in the blood and organs of infected patients. New compounds to activate these latent reserv
Externí odkaz:
https://doaj.org/article/1507cea679ca41d098107ae84e874c04
Autor:
Blanca V. Rodriguez, Yi Wen, Erin N. Shirk, Samuel Vazquez, Olesia Gololobova, Amanda Maxwell, Jessica Plunkard, Natalie Castell, Bess Carlson, Suzanne E. Queen, Jessica M. Izzi, Tom A. P. Driedonks, Kenneth W. Witwer
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) can be loaded with therapeutic cargo and engineered for retention by specific body sites; therefore, they have great potential for targeted delivery of biomolecules to treat diseases. However, the pharmacokinetic
Externí odkaz:
https://doaj.org/article/4e84319788184f198630457bb298ff30
Autor:
Tom Driedonks, Linglei Jiang, Bess Carlson, Zheng Han, Guanshu Liu, Suzanne E. Queen, Erin N. Shirk, Olesia Gololobova, Zhaohao Liao, Lyle H. Nyberg, Gabriela Lima, Liliia Paniushkina, Marta Garcia‐Contreras, Kayla Schonvisky, Natalie Castell, Mitchel Stover, Selena Guerrero‐Martin, Riley Richardson, Barbara Smith, Vasiliki Mahairaki, Charles P. Lai, Jessica M. Izzi, Eric K. Hutchinson, Kelly A. M. Pate, Kenneth W. Witwer
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 10, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded with therapeutic molecules and engineered for retention by specific tissues. However, questions remain on optimal dosing, administration and pharmacoki
Externí odkaz:
https://doaj.org/article/6033ca7d2ad846969268515852ea161c
Autor:
Rebecca T. Veenhuis, Dionna W. Williams, Erin N. Shirk, Celina M. Abreu, Edna A. Ferreira, Jennifer M. Coughlin, Todd T. Brown, Pauline M. Maki, Kathryn Anastos, Joan W. Berman, Janice E. Clements, Leah H. Rubin
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
BACKGROUND Identifying a quantitative biomarker of neuropsychiatric dysfunction in people with HIV (PWH) remains a significant challenge in the neuroHIV field. The strongest evidence to date implicates the role of monocytes in central nervous system
Externí odkaz:
https://doaj.org/article/d4c51297b11e4dc0a27832462d3f699a
Autor:
Tom, Driedonks, Linglei, Jiang, Bess, Carlson, Zheng, Han, Guanshu, Liu, Suzanne E, Queen, Erin N, Shirk, Olesia, Gololobova, Zhaohao, Liao, Lyle H, Nyberg, Gabriela, Lima, Liliia, Paniushkina, Marta, Garcia-Contreras, Kayla, Schonvisky, Natalie, Castell, Mitchel, Stover, Selena, Guerrero-Martin, Riley, Richardson, Barbara, Smith, Vasiliki, Machairaki, Charles P, Lai, Jessica M, Izzi, Eric K, Hutchinson, Kelly A M, Pate, Kenneth W, Witwer
Publikováno v:
Journal of extracellular biology. 1(10)
Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded with therapeutic molecules and engineered for retention by specific tissues. However, questions remain on optimal dosing, administration, and pharmacokinetics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::186db7b0801d2cdbc8ec1d1e6fdd2488
https://pubmed.ncbi.nlm.nih.gov/36591537
https://pubmed.ncbi.nlm.nih.gov/36591537
Autor:
Rebecca T. Veenhuis, Celina M. Abreu, Pedro A. G. Costa, Edna A. Ferreira, Janaysha Ratliff, Lily Pohlenz, Erin N. Shirk, Leah H. Rubin, Joel N. Blankson, Lucio Gama, Janice E. Clements
Publikováno v:
Nature Microbiology. 8:833-844
The development of persistent cellular reservoirs of latent human immunodeficiency virus (HIV) is a critical obstacle to viral eradication since viral rebound takes place once anti-retroviral therapy (ART) is interrupted. Previous studies show that H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2794716accc66644b453f0e9c205d65f
https://doi.org/10.1038/s41564-023-01349-3
https://doi.org/10.1038/s41564-023-01349-3
Autor:
Celina M. Abreu, Rebecca T. Veenhuis, Claudia R. Avalos, Shelby Graham, Daymond R. Parrilla, Edna A. Ferreira, Suzanne E. Queen, Erin N. Shirk, Brandon T. Bullock, Ming Li, Kelly A. Metcalf Pate, Sarah E. Beck, Lisa M. Mangus, Joseph L. Mankowski, Feilim Mac Gabhann, Shelby L. O’Connor, Lucio Gama, Janice E. Clements
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Human immunodeficiency virus (HIV) eradication or long-term suppression in the absence of antiretroviral therapy (ART) requires an understanding of all viral reservoirs that could contribute to viral rebound after ART interruption. CD4 T cel
Externí odkaz:
https://doaj.org/article/bcbb18ba10ce487f8c86493a4d42ad7b
Autor:
Blanca V. Rodriguez, Yi Wen, Erin N. Shirk, Samuel Vazquez, Olesia Gololobova, Amanda Maxwell, Jessica Plunkard, Natalie Castell, Bess Carlson, Suzanne E. Queen, Jessica M. Izzi, Tom A.P. Driedonks, Kenneth W. Witwer
Extracellular vesicles (EVs) can be loaded with therapeutic cargo and engineered for retention by specific body sites; therefore, they have great potential for targeted delivery of biomolecules to treat diseases. However, the pharmacokinetics and bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95c89ddcbaad767f54576d75d9ce36ff
https://doi.org/10.1101/2023.05.11.540421
https://doi.org/10.1101/2023.05.11.540421
Autor:
Claudia R. Avalos, Celina M. Abreu, Suzanne E. Queen, Ming Li, Sarah Price, Erin N. Shirk, Elizabeth L. Engle, Ellen Forsyth, Brandon T. Bullock, Feilim Mac Gabhann, Stephen W. Wietgrefe, Ashley T. Haase, M. Christine Zink, Joseph L. Mankowski, Janice E. Clements, Lucio Gama
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT A human immunodeficiency virus (HIV) infection cure requires an understanding of the cellular and anatomical sites harboring virus that contribute to viral rebound upon treatment interruption. Despite antiretroviral therapy (ART), HIV-associ
Externí odkaz:
https://doaj.org/article/cc2e12c107704e4d86a6f1bc8f4383ea