Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Erin N, Shirk"'
Autor:
Blanca V. Rodriguez, Yi Wen, Erin N. Shirk, Samuel Vazquez, Olesia Gololobova, Amanda Maxwell, Jessica Plunkard, Natalie Castell, Bess Carlson, Suzanne E. Queen, Jessica M. Izzi, Tom A. P. Driedonks, Kenneth W. Witwer
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) can be loaded with therapeutic cargo and engineered for retention by specific body sites; therefore, they have great potential for targeted delivery of biomolecules to treat diseases. However, the pharmacokinetic
Externí odkaz:
https://doaj.org/article/4e84319788184f198630457bb298ff30
Autor:
Tom Driedonks, Linglei Jiang, Bess Carlson, Zheng Han, Guanshu Liu, Suzanne E. Queen, Erin N. Shirk, Olesia Gololobova, Zhaohao Liao, Lyle H. Nyberg, Gabriela Lima, Liliia Paniushkina, Marta Garcia‐Contreras, Kayla Schonvisky, Natalie Castell, Mitchel Stover, Selena Guerrero‐Martin, Riley Richardson, Barbara Smith, Vasiliki Mahairaki, Charles P. Lai, Jessica M. Izzi, Eric K. Hutchinson, Kelly A. M. Pate, Kenneth W. Witwer
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 10, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded with therapeutic molecules and engineered for retention by specific tissues. However, questions remain on optimal dosing, administration and pharmacoki
Externí odkaz:
https://doaj.org/article/6033ca7d2ad846969268515852ea161c
Autor:
Tom, Driedonks, Linglei, Jiang, Bess, Carlson, Zheng, Han, Guanshu, Liu, Suzanne E, Queen, Erin N, Shirk, Olesia, Gololobova, Zhaohao, Liao, Lyle H, Nyberg, Gabriela, Lima, Liliia, Paniushkina, Marta, Garcia-Contreras, Kayla, Schonvisky, Natalie, Castell, Mitchel, Stover, Selena, Guerrero-Martin, Riley, Richardson, Barbara, Smith, Vasiliki, Machairaki, Charles P, Lai, Jessica M, Izzi, Eric K, Hutchinson, Kelly A M, Pate, Kenneth W, Witwer
Publikováno v:
Journal of extracellular biology. 1(10)
Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded with therapeutic molecules and engineered for retention by specific tissues. However, questions remain on optimal dosing, administration, and pharmacokinetics.
Autor:
Rebecca T. Veenhuis, Dionna W. Williams, Erin N. Shirk, Celina M. Abreu, Edna A. Ferreira, Jennifer M. Coughlin, Todd T. Brown, Pauline M. Maki, Kathryn Anastos, Joan W. Berman, Janice E. Clements, Leah H. Rubin
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
BACKGROUND Identifying a quantitative biomarker of neuropsychiatric dysfunction in people with HIV (PWH) remains a significant challenge in the neuroHIV field. The strongest evidence to date implicates the role of monocytes in central nervous system
Externí odkaz:
https://doaj.org/article/d4c51297b11e4dc0a27832462d3f699a
Autor:
Rebecca T. Veenhuis, Celina M. Abreu, Pedro A. G. Costa, Edna A. Ferreira, Janaysha Ratliff, Lily Pohlenz, Erin N. Shirk, Leah H. Rubin, Joel N. Blankson, Lucio Gama, Janice E. Clements
Publikováno v:
Nature Microbiology. 8:833-844
The development of persistent cellular reservoirs of latent human immunodeficiency virus (HIV) is a critical obstacle to viral eradication since viral rebound takes place once anti-retroviral therapy (ART) is interrupted. Previous studies show that H
Autor:
Blanca V. Rodriguez, Yi Wen, Erin N. Shirk, Samuel Vazquez, Olesia Gololobova, Amanda Maxwell, Jessica Plunkard, Natalie Castell, Bess Carlson, Suzanne E. Queen, Jessica M. Izzi, Tom A.P. Driedonks, Kenneth W. Witwer
Extracellular vesicles (EVs) can be loaded with therapeutic cargo and engineered for retention by specific body sites; therefore, they have great potential for targeted delivery of biomolecules to treat diseases. However, the pharmacokinetics and bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95c89ddcbaad767f54576d75d9ce36ff
https://doi.org/10.1101/2023.05.11.540421
https://doi.org/10.1101/2023.05.11.540421
Autor:
Celina M. Abreu, Rebecca T. Veenhuis, Claudia R. Avalos, Shelby Graham, Daymond R. Parrilla, Edna A. Ferreira, Suzanne E. Queen, Erin N. Shirk, Brandon T. Bullock, Ming Li, Kelly A. Metcalf Pate, Sarah E. Beck, Lisa M. Mangus, Joseph L. Mankowski, Feilim Mac Gabhann, Shelby L. O’Connor, Lucio Gama, Janice E. Clements
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Human immunodeficiency virus (HIV) eradication or long-term suppression in the absence of antiretroviral therapy (ART) requires an understanding of all viral reservoirs that could contribute to viral rebound after ART interruption. CD4 T cel
Externí odkaz:
https://doaj.org/article/bcbb18ba10ce487f8c86493a4d42ad7b
Autor:
Natalie Castell, Selena M. Guerrero-Martin, Leah H. Rubin, Erin N. Shirk, Jacqueline K. Brockhurst, Claire E. Lyons, Kevin M. Najarro, Suzanne E. Queen, Bess W. Carlson, Robert J. Adams, Craig N. Morrell, Lucio Gama, David R. Graham, Christine Zink, Joseph L. Mankowski, Janice E. Clements, Kelly A. Metcalf Pate
Publikováno v:
Psychosomatic medicine. 84(8)
Simian immunodeficiency virus (SIV) infection of macaques recapitulates many aspects of HIV pathogenesis and is similarly affected by both genetic and environmental factors. Psychosocial stress is associated with immune system dysregulation and worse
Autor:
Claudia R. Avalos, Celina M. Abreu, Suzanne E. Queen, Ming Li, Sarah Price, Erin N. Shirk, Elizabeth L. Engle, Ellen Forsyth, Brandon T. Bullock, Feilim Mac Gabhann, Stephen W. Wietgrefe, Ashley T. Haase, M. Christine Zink, Joseph L. Mankowski, Janice E. Clements, Lucio Gama
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT A human immunodeficiency virus (HIV) infection cure requires an understanding of the cellular and anatomical sites harboring virus that contribute to viral rebound upon treatment interruption. Despite antiretroviral therapy (ART), HIV-associ
Externí odkaz:
https://doaj.org/article/cc2e12c107704e4d86a6f1bc8f4383ea
Autor:
Erin N. Shirk, Sarah E. Beck, Lisa M. Mangus, Kelly A. Metcalf Pate, Lucio Gama, Joseph L. Mankowski, Suzanne E. Queen, Janice E. Clements, Celina M. Abreu
Publikováno v:
AIDS. 33:S181-S188
The current review examines the role of brain macrophages, that is perivascular macrophages and microglia, as a potential viral reservoir in antiretroviral therapy (ART) treated, simian immunodeficiency virus (SIV)-infected macaques. The role, if any