Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Erin Morris Richard"'
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130042 (2015)
Aminoacyl-tRNA synthetases (AARSs) constitute a family of RNA-binding proteins, that participate in the translation of the genetic code, by covalently linking amino acids to appropriate tRNAs. Due to their fundamental importance for cell life, AARSs
Externí odkaz:
https://doaj.org/article/eea86ce693cd445cbee056d196b6dafd
Autor:
Erin Morris Richard, Thirumagal Thiyagarajan, Marlene A Bunni, Fahmin Basher, Patrick O Roddy, Leah J Siskind, Paul J Nietert, Tamara K Nowling
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75175 (2013)
Systemic Lupus erythematosus (SLE) is an autoimmune disease caused, in part, by abnormalities in cells of the immune system including B and T cells. Genetically reducing globally the expression of the ETS transcription factor FLI1 by 50% in two lupus
Externí odkaz:
https://doaj.org/article/f8f21b58e3e24083812959898d64c66a
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130042 (2015)
PLoS ONE
PLoS ONE
Aminoacyl-tRNA synthetases (AARSs) constitute a family of RNA-binding proteins, that participate in the translation of the genetic code, by covalently linking amino acids to appropriate tRNAs. Due to their fundamental importance for cell life, AARSs
Autor:
Marlene A. Bunni, Leah J. Siskind, Fahmin Basher, Paul J. Nietert, Patrick Roddy, Erin Morris Richard, Tamara K. Nowling, Thirumagal Thiyagarajan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e75175 (2013)
PLoS ONE, Vol 8, Iss 9, p e75175 (2013)
Systemic Lupus erythematosus (SLE) is an autoimmune disease caused, in part, by abnormalities in cells of the immune system including B and T cells. Genetically reducing globally the expression of the ETS transcription factor FLI1 by 50% in two lupus
Publikováno v:
The Journal of Immunology. 186:44.30-44.30
The Ets factor Fli1 is implicated as a key modulator of lupus disease expression. Lowering the global levels of Fli1 in lupus mouse models or lowering the levels of Fli1 in hematopoietic cells in MRL/lpr lupus mice significantly improved kidney disea