Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Erin Metzger"'
Autor:
Joy Garrett, Erin Metzger, Mark W. Dewhirst, Karen E. Pollok, John J. Turchi, Isabelle C. Le Poole, Kira Couch, Logan Lew, Anthony Sinn, Jeffrey M. Zaleski, Joseph R. Dynlacht
Publikováno v:
International Journal of Hyperthermia, Vol 39, Iss 1, Pp 405-413 (2022)
Background Enediynes are anti-cancer agents that are highly cytotoxic due to their propensity for low thermal activation of radical generation. The diradical intermediate produced from Bergman cyclization of the enediyne moiety may induce DNA damage
Externí odkaz:
https://doaj.org/article/7245f922c324473d88674548fe76d2e9
Autor:
Joy E. Garrett, Erin Metzger, Katelyn Schmitt, Sarai Soto, Samantha Northern, Laura Kryah, Misbah Irfan, Susan Rice, Mary Brown, Jeffrey M. Zaleski, Joseph R. Dynlacht
Publikováno v:
Radiat Res
Enediyne natural products are a class of compounds that were recognized for their potential as chemotherapeutic agents many years ago, but found to be highly cytotoxic due to their propensity for low thermal activation. Bergman cyclization of the ene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f85e363e39da3296e877f0f7033205c
https://doi.org/10.1667/rr15433.1
https://doi.org/10.1667/rr15433.1