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pro vyhledávání: '"Erin Marie O. Kimbrough"'
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-29 (2021)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
The immune system is the core defense against cancer development and progression. Failure of the immune system to recognize and eliminate malignant cells plays an important role in the pathogenesis of cancer. Tumor cells evade immune recognition, in
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-31 (2021)
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-31 (2021)
Co-stimulatory and co-inhibitory molecules play a critical role in T cell function. Tumor cells escape immune surveillance by promoting immunosuppression. Immunotherapy targeting inhibitory molecules like anti-CTLA-4 and anti-PD-1/PD-L1 were develope