Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Erin M McConnell"'
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22239 (2011)
Systemic administration of the noncompetitive NMDA-receptor antagonist, MK-801, has been proposed to model cognitive deficits similar to those seen in patients with schizophrenia. The present work investigated the ability of a dopamine-binding DNA ap
Externí odkaz:
https://doaj.org/article/cb7ed9763c0f4c37bf5d3919d9e57ae9
Publikováno v:
Advanced Agrochem, Vol 2, Iss 3, Pp 221-230 (2023)
Mycotoxins are small molecules produced by fungi that contaminate crops and cause notable health effects for humans, owing to their inherent toxicity. Aflatoxins are among the most potent mycotoxins, with aflatoxin B1 and M1 being the most concerning
Externí odkaz:
https://doaj.org/article/05c105d5bd164acab35568ed26027578
Autor:
Kaylin G. Earnest, Erin M. McConnell, Eman M. Hassan, Mark Wunderlich, Bahareh Hosseinpour, Bianca S. Bono, Melissa J. Chee, James C. Mulloy, William G. Willmore, Maria C. DeRosa, Edward J. Merino
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Current classes of cancer therapeutics have negative side effects stemming from off-target cytotoxicity. One way to avoid this would be to use a drug delivery system decorated with targeting moieties, such as an aptamer, if a targeted aptame
Externí odkaz:
https://doaj.org/article/17d8b5d0007c474daed087ef61f4e1db
Autor:
Liqun He, Daniel R. Tessier, Kyle Briggs, Matthaios Tsangaris, Martin Charron, Erin M. McConnell, Dmytro Lomovtsev, Vincent Tabard-Cossa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The concentration of a biomarker in solution can be determined by counting single molecules. Here the authors report a digital immunoassay scheme with solid-state nanopore readout to quantify a target protein and use this to measure thyroid-stimulati
Externí odkaz:
https://doaj.org/article/49741f2631fc4bbb81a308132e47132a
Autor:
Shuwen Qian, Erin M. McConnell, Meghan Rothenbroker, Jimmy Gu, Simina Alungulesa, Louis Godbout, Yingfu Li
Publikováno v:
Analysis & Sensing.
Autor:
Annemieke, Aartsma-Rus, Alejandro, Garanto, Willeke, van Roon-Mom, Erin M, McConnell, Victoria, Suslovitch, Winston X, Yan, Jonathan K, Watts, Timothy W, Yu
Publikováno v:
Nucleic acid therapeutics.
Antisense oligonucleotides (ASOs) can modulate pre-mRNA splicing. This offers therapeutic opportunities for numerous genetic diseases, often in a mutation-specific and sometimes even individual-specific manner. Developing therapeutic ASOs for as few
Autor:
Dmytro Lomovtsev, Kyle Briggs, Matthaios Tsangaris, Erin M. McConnell, Daniel R. Tessier, Vincent Tabard-Cossa, Martin Charron, Liqun He
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Single-molecule counting is the most accurate and precise method for determining the concentration of a biomarker in solution and is leading to the emergence of digital diagnostic platforms enabling precision medicine. In principle, solid-state nanop
Autor:
Sahar Esmaeili Samani, Dingran Chang, Meghan Rothenbroker, Yingfu Li, Carlos D. M. Filipe, Erin M. McConnell
Publikováno v:
Analysis & Sensing. 1:95-100
Autor:
Greg O. Cron, Maria C. DeRosa, Anna Koudrina, Erin M. McConnell, Suzan Chen, Eve C. Tsai, Joseph A. Zurakowski
Publikováno v:
ACS Applied Materials & Interfaces. 13:9412-9424
Objective: An important clinical question in the determination of the extent of thrombosis-related vascular conditions is the identification of blood clot location. Fibrin is a major molecular constituent of blood clots and can, therefore, be utilize