Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Erin M, Guest"'
Autor:
Erin M. Guest, John A. Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Infants less than 1 year old diagnosed with KMT2A-rearranged (KMT2A-r) acute lymphoblastic leukemia (ALL) are at high risk of remission failure, relapse, and death due to leukemia, despite intensive therapies. Infant KMT2A-r ALL blasts are characteri
Externí odkaz:
https://doaj.org/article/b91198f427bc4dd39ad94aff06c2ddf3
Autor:
Erin M. Guest, John A. Kairalla, Joanne M. Hilden, ZoAnn E. Dreyer, Andrew J. Carroll, Nyla A. Heerema, Cindy Y. Wang, Meenakshi Devidas, Lia Gore, Wanda L. Salzer, Naomi J. Winick, William L. Carroll, Elizabeth A. Raetz, Michael Borowitz, Mignon L. Loh, Stephen P. Hunger, Patrick A. Brown
Publikováno v:
Haematologica, Vol 107, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/6f75c85ff88943d48d1cd90df26deea7
Autor:
Sumit Gupta, Yunfeng Dai, Zhiguo Chen, Lena E Winestone, David T Teachey, Kira Bona, Richard Aplenc, Karen R Rabin, Patrick Zweidler-McKay, Andrew J Carroll, Nyla A Heerema, Julie Gastier-Foster, Michael J Borowitz, Brent L Wood, Kelly W Maloney, Leonard A Mattano, Eric C Larsen, Anne L Angiolillo, Michael J Burke, Wanda L Salzer, Stuart S Winter, Patrick A Brown, Erin M Guest, Kimberley P Dunsmore, John A Kairalla, Naomi J Winick, William L Carroll, Elizabeth A Raetz, Stephen P Hunger, Mignon L Loh, Meenakshi Devidas
Publikováno v:
The Lancet Haematology. 10:e129-e141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d3f3c94a68370726e192b0bfb3e2398
https://doi.org/10.1016/s2352-3026(22)00371-4
https://doi.org/10.1016/s2352-3026(22)00371-4
Autor:
Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, James W. Davenport, Yuxuan Hu, Qin Zhu, Kai Wang, Clara Libbrecht, Alex Felmeister, Isaiah Rozich, Yang-yang Ding, Stephen P. Hunger, Carolyn A. Felix, Hao Wu, Patrick A. Brown, Erin M. Guest, David M. Barrett, Kathrin M. Bernt, Kai Tan
Publikováno v:
Blood. 139:2198-2211
KMT2A-rearranged (KMT2A-r) infant acute lymphoblastic leukemia (ALL) is a devastating malignancy with a dismal outcome, and younger age at diagnosis is associated with increased risk of relapse. To discover age-specific differences and critical drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0db1cf888d7f6fc91965ddb3925788
https://doi.org/10.1182/blood.2021013442
https://doi.org/10.1182/blood.2021013442
Autor:
Richard Aplenc, Todd A. Alonzo, Jessica A. Pollard, Alan S. Gamis, E. Anders Kolb, Lisa Eidenschink Brodersen, Susana C. Raimondi, Mike R Loken, Erin M. Guest, Soheil Meshinchi, Betsy A. Hirsch, Robert B. Gerbing
Publikováno v:
Journal of Clinical Oncology. 39:3149-3160
PURPOSE We investigated the impact of the CD33-targeted agent gemtuzumab ozogamicin (GO) on survival in pediatric patients with KMT2A-rearranged ( KMT2A-r) acute myeloid leukemia (AML) enrolled in the Children's Oncology Group trial AAML0531 ( NCT014
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4de333bce4c398519e4670de839ac60a
https://doi.org/10.1200/jco.20.03048
https://doi.org/10.1200/jco.20.03048
Autor:
Laurence C. Cheung, Carlos Aya-Bonilla, Mark N. Cruickshank, Sung K. Chiu, Vincent Kuek, Denise Anderson, Grace-Alyssa Chua, Sajla Singh, Joyce Oommen, Emanuela Ferrari, Anastasia M. Hughes, Jette Ford, Elena Kunold, Maria C. Hesselman, Frederik Post, Kelly E. Faulk, Erin H. Breese, Erin M. Guest, Patrick A. Brown, Mignon L. Loh, Richard B. Lock, Ursula R. Kees, Rozbeh Jafari, Sébastien Malinge, Rishi S. Kotecha
Publikováno v:
Leukemia.
Infants with KMT2A-rearranged B-cell acute lymphoblastic leukemia (ALL) have a dismal prognosis. Survival outcomes have remained static in recent decades despite treatment intensification and novel therapies are urgently required. KMT2A-rearranged in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3511827709e3b75fa6fcbd43736a54e
https://pubmed.ncbi.nlm.nih.gov/36380143
https://pubmed.ncbi.nlm.nih.gov/36380143
Autor:
Zhenrui Li, Anuradha Roy, Xiazhen Yu, Linhao Ruan, Xi C. He, Prashant Deshmukh, G. Sitta Sittampalam, Alan S. Gamis, Melinda Broward, Xiuling Lu, Jacqelyn Nemechek, Pengxu Qian, John M. Perry, Robin Ryan, Linheng Li, Andrea Moran, Fang Tao, Keith J. August, Mark Hembree, Thanh Huyen Tran, Zhiquan He, Rajeswari M. Kasi, Meng Zhao, Aparna Venkatraman, Dong Xu, Erin M. Guest, Debra Dukes, Chi Thanh Nguyen, Shiyuan Chen, Jennifer Pace, Scott Weir, Sheng Ding, Andrew K. Godwin, Ariel Paulson, Tara L. Lin, Kealan Schroeder
Publikováno v:
Nat Cell Biol
Leukaemia stem cells (LSCs) underlie cancer therapy resistance but targeting these cells remains difficult. The Wnt-β-catenin and PI3K-Akt pathways cooperate to promote tumorigenesis and resistance to therapy. In a mouse model in which both pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5061166ebd5f8b130688942171cc35b6
https://doi.org/10.1038/s41556-020-0507-y
https://doi.org/10.1038/s41556-020-0507-y
Publikováno v:
Clinical Management of Acute Lymphoblastic Leukemia ISBN: 9783030851460
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cd081f74536a66a9ecebfb42b6fc590
https://doi.org/10.1007/978-3-030-85147-7_6
https://doi.org/10.1007/978-3-030-85147-7_6
Autor:
Heather E. Stefanski, Liora M. Schultz, Yasemin Goksenin, Michelle L. Hermiston, Vanessa A Fabrizio, Christina Baggott, Nicole Karras, M. Christa Krupski, Vasant Chinnabhandar, Steven P. Margossian, Holly L Pacenta, Christine L Phillips, Douglas Myers, Kevin J. Curran, Lauren Pommert, Rachel Wilcox, Patrick A. Brown, Muna Qayed, Amy K. Keating, Amy Moskop, Erin H. Breese, Michael R. Verneris, Jenna Rossoff, Cara A Rabik, Crystal L. Mackall, Theodore W. Laetsch, Prakash Satwani, Snehit Prabhu, Julie-An Talano, Erin M. Guest
Publikováno v:
Blood advances, vol 6, iss 14
Infants with B-cell acute lymphoblastic leukemia (B-ALL) have poor outcomes because of chemotherapy resistance leading to high relapse rates. Tisagenlecleucel, a CD19-directed chimeric antigen receptor T-cell (CART) therapy, is US Food and Drug Admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef986cad0af2de8f8119aa635fe3033d
https://pubmed.ncbi.nlm.nih.gov/35580324
https://pubmed.ncbi.nlm.nih.gov/35580324
Autor:
Erin M, Guest, John A, Kairalla, Joanne M, Hilden, ZoAnn E, Dreyer, Andrew J, Carroll, Nyla A, Heerema, Cindy Y, Wang, Meenakshi, Devidas, Lia, Gore, Wanda L, Salzer, Naomi J, Winick, William L, Carroll, Elizabeth A, Raetz, Michael, Borowitz, Mignon L, Loh, Stephen P, Hunger, Patrick A, Brown
Publikováno v:
Haematologica. 107(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59856778501c7e155a78e8e1058f41f4
https://pubmed.ncbi.nlm.nih.gov/35172563
https://pubmed.ncbi.nlm.nih.gov/35172563