Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Erin Lexner"'
Autor:
Akshita B. Bhatt, Thomas D. Wright, Van Barnes, Suravi Chakrabarty, Margarite D. Matossian, Erin Lexner, Deniz A. Ucar, Lucio Miele, Patrick T. Flaherty, Matthew E. Burow, Jane E. Cavanaugh
Publikováno v:
Translational Oncology, Vol 14, Iss 6, Pp 101046- (2021)
The epithelial to mesenchymal transition (EMT) is characterized by a loss of cell polarity, a decrease in the epithelial cell marker E-cadherin, and an increase in mesenchymal markers including the zinc-finger E-box binding homeobox (ZEB1). The EMT i
Externí odkaz:
https://doaj.org/article/741a151b8f16497b82667f09411e6156
Autor:
Jane E. Cavanaugh, Patrick T. Flaherty, Lucio Miele, Margarite D. Matossian, Thomas D. Wright, Van Barnes, Matthew E. Burow, Deniz A. Ucar, Suravi Chakrabarty, Akshita B. Bhatt, Erin Lexner
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 6, Pp 101046-(2021)
Translational Oncology, Vol 14, Iss 6, Pp 101046-(2021)
Highlights • ERK1/2 and ERK5 pathway inhibition induces mesenchymal to epithelial transition in breast cancer. • ERK5 is endogenously active and localized in the nucleus of TNBC cells. • Dual ERK5 and ERK1/2 or AKT inhibition is a relevant stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae42aa562776ae0dc9e5bd5217344a1a
https://lirias.kuleuven.be/handle/20.500.12942/707698
https://lirias.kuleuven.be/handle/20.500.12942/707698
