Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Erin L. Volk"'
Publikováno v:
BioTechniques, Vol 35, Iss 5, Pp 926-932 (2003)
Externí odkaz:
https://doaj.org/article/691847ca3dcf4e888bb0e874aef7442c
Supplementary Data from The MDM2-A Splice Variant of MDM2 Alters Transformation In vitro and the Tumor Spectrum in Both Arf- and p53-Null Models of Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a20c2b4548b632e8e6eff96101020d
https://doi.org/10.1158/1541-7786.22519486
https://doi.org/10.1158/1541-7786.22519486
Publikováno v:
Disease Models & Mechanisms. 2:47-55
SUMMARY MDM2 is the predominant negative regulator of p53 that functions to maintain the appropriate level of expression and activity of this central tumor suppressor. Mdm2-a is a commonly identified splice variant of Mdm2; however, its physiological
Publikováno v:
Cancer Biology & Therapy. 7:38-44
MDM2 is an oncoprotein best characterized for its role in the inactivation and degradation of the p53 tumor suppressor. However, MDM2 has many other binding partners and its p53-independent role in the regulation of cell growth and survival appears t
Publikováno v:
BioTechniques. 35:926-932
Autor:
Chih-Hsin Yang, Erin L. Volk, Erasmus Schneider, Yao-Chang Chen, Min-Liang Kuo, Emmanuelle Rocchi
Publikováno v:
Biochemical Pharmacology. 60:831-837
We have previously described a mitoxantrone-resistant MCF7 cell line that is cross-resistant to topotecan, 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11), and 9-aminocamptothecin, but not to camptothecin. A novel mechanis
Autor:
Andrew A. Reilly, Frederick K. Chu, Gary M. Winslow, Konstantin Shilo, Eric J. Yager, Erin L Volk
Publikováno v:
Infection and Immunity. 68:2187-2195
It is generally accepted that cellular, but not humoral immunity, plays an important role in host defense against intracellular bacteria. However, studies of some of these pathogens have provided evidence that antibodies can provide immunity if prese
MDM2-A is a common splice variant of murine double minute 2 (MDM2) that is frequently detected in many tumor types. Our previous work has characterized MDM2-A as an activator of p53, and therefore, in a wild-type p53 background, this splice variant w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b73e09a130d052e79353becf0bdcd1c
https://europepmc.org/articles/PMC3526663/
https://europepmc.org/articles/PMC3526663/
Autor:
Erin L, Volk, Erasmus, Schneider
Publikováno v:
Cancer research. 63(17)
The existence of an ATP-dependent methotrexate (MTX) efflux mechanism has long been postulated; however, until recently, the molecular components were largely unknown. We have previously demonstrated a role for the ATP-binding cassette transporter br
Autor:
Erasmus Schneider, Thomas Litman, Emmanuelle Rocchi, Alexey Khodjakov, Susan E. Bates, Chih-Hsin Yang, Erin L. Volk
Publikováno v:
Biochemical and biophysical research communications. 271(1)
The products of the ABC gene family can be generally classified as either full-transporters of half-transporters. Full-transporters are expressed in the plasma membrane, whereas half-transporters are usually found in intracellular membranes. Recently