Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Erin L. Roberts"'
Autor:
Hayley M. Todesco, Chris Gafuik, Cini M. John, Erin L. Roberts, Breanna S. Borys, Alexis Pawluk, Michael S. Kallos, Kyle G. Potts, Douglas J. Mahoney
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101189- (2024)
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic highlighted the importance of vaccine innovation in public health. Hundreds of vaccines built on numerous technology platforms have been rapidly developed against SARS-CoV-2 si
Externí odkaz:
https://doaj.org/article/fdb3ab36b00a41dab43e9dd75f45b765
Publikováno v:
ACS Materials Au, Vol 3, Iss 5, Pp 418-441 (2023)
Externí odkaz:
https://doaj.org/article/247d2ee6f5f84f3dbfb3ae79dca909a7
Autor:
Breanna S. Borys, Tania So, James Colter, Tiffany Dang, Erin L. Roberts, Tamas Revay, Leila Larijani, Roman Krawetz, Ian Lewis, Bob Argiropoulos, Derrick E. Rancourt, Sunghoon Jung, Yas Hashimura, Brian Lee, Michael S. Kallos
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 1036-1052 (2020)
Abstract Human induced pluripotent stem cells (hiPSCs) have generated a great deal of attention owing to their capacity for self‐renewal and differentiation into the three germ layers of the body. Their discovery has facilitated a new era in biomed
Externí odkaz:
https://doaj.org/article/12cda13c70c14445b8dbe352327b75a7
Autor:
Erin L. Roberts, Tiffany Dang, Sarah I. M. Lepage, Amir Hamed Alizadeh, Tylor Walsh, Thomas G. Koch, Michael S. Kallos
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-16 (2019)
Abstract Equine mesenchymal stromal cells (MSCs) are increasingly investigated for their clinical therapeutic utility. Such cell-based treatments can require cell numbers in the millions or billions, with conventional expansion methods using static T
Externí odkaz:
https://doaj.org/article/a2640560a5154563afa31db56fe355b7
Publikováno v:
Biotechnology and Bioengineering. 119:3062-3078
Mesenchymal stromal cells (MSC) are a promising platform for regenerative medicine applications because of their multilineage differentiation abilities and ease of collection, isolation, and growth ex vivo. To meet the demand for clinical application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fff3e8fec6ef4e3616efc61de2ab1b
https://doi.org/10.1002/bit.28210
https://doi.org/10.1002/bit.28210
Autor:
Sina Ehsani, Arindom Sen, Michael S. Kallos, Brett Abraham, Kunal Karan, Erin L. Roberts, Anil K. Mehrotra
Publikováno v:
The Canadian Journal of Chemical Engineering. 99:2262-2281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f4d01f64596a30621d38ba97eb14969
https://doi.org/10.1002/cjce.24192
https://doi.org/10.1002/cjce.24192
Autor:
Sunghoon Jung, Erin L. Roberts, Michael S. Kallos, Yas Hashimura, Tamas Revay, Tania So, Tiffany Dang, Brian Lee, Leila Larijani, James Colter, Breanna S. Borys, Ian A. Lewis, Derrick E. Rancourt, Roman Krawetz, Bob Argiropoulos
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 1036-1052 (2020)
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 1036-1052 (2020)
Human induced pluripotent stem cells (hiPSCs) have generated a great deal of attention owing to their capacity for self‐renewal and differentiation into the three germ layers of the body. Their discovery has facilitated a new era in biomedicine for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9277d9eb352451109581b72c6df11f87
http://europepmc.org/articles/PMC7445025
http://europepmc.org/articles/PMC7445025
Autor:
Breanna S. Borys, Derrick E. Rancourt, Michael S. Kallos, Leah Ferrie, Erin L. Roberts, Tania So, Brett Abraham, Leila Larijani, Roman Krawetz
Publikováno v:
Biotechnology and Bioengineering. 117:1316-1328
Embryonic stem cells (ESCs) have almost unlimited proliferation capacity in vitro and can retain the ability to contribute to all cell lineages, making them an ideal platform material for cell-based therapies. ESCs are traditionally cultured in stati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d803676e7be8480f7635e73c7deb2216
https://doi.org/10.1002/bit.27279
https://doi.org/10.1002/bit.27279
Autor:
Breanna S. Borys, Derrick E. Rancourt, Charlie Yu-Ming Hsu, Tiffany Dang, Leili Rohani, An Le, Ian D. Gates, Michael S. Kallos, Alexander A. Wyma, Erin L. Roberts
Publikováno v:
Journal of Biotechnology. 304:16-27
Computational fluid dynamics (CFD) modeling can be applied to understand hydrodynamics in stirred suspension bioreactors, which can in turn affect cell viability, proliferation, pluripotency and differentiation. In this study, we developed a CFD mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b94fe43a337f2a376192c6d57c9709d
https://doi.org/10.1016/j.jbiotec.2019.08.002
https://doi.org/10.1016/j.jbiotec.2019.08.002
Publikováno v:
Biochemical Engineering Journal. 133:157-167
The use of stirred suspension bioreactors as tools in large-scale stem cell expansion is becoming increasingly popular. A change in bioreactor scale results in altered hydrodynamic properties which greatly affect the cell product, particularly if the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf76891e2a7dbdc8d15e9d026bab155e
https://doi.org/10.1016/j.bej.2018.02.005
https://doi.org/10.1016/j.bej.2018.02.005