Výsledky vyhledávání - "Erin L. Garcia"

GPR37 Surface Expression Enhancement via N-Terminal Truncation or Protein−Protein Interactions

Autor: Randy A. Hall, Rebecca C. Meyer, Erin L. Garcia, Jill H. Dunham

Publikováno v: Biochemistry. 48:10286-10297

GPR37, also known as the parkin-associated endothelin-like receptor (Pael-R), is an orphan G-protein-coupled receptor (GPCR) that exhibits poor plasma membrane expression when expressed in most cell types. We sought to find ways to enhance GPR37 traf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb166104d5e5b2f5f8f9beec5d345af4
https://doi.org/10.1021/bi9013775

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The Protein Scaffold NHERF-1 Controls the Amplitude and Duration of Localized Protein Kinase D Activity

Autor: Taketoshi Kajimoto, Alexandra C. Newton, Randy A. Hall, Maya T. Kunkel, Erin L. Garcia

Publikováno v: Journal of Biological Chemistry. 284:24653-24661

Protein kinase D (PKD) transduces an abundance of signals downstream of diacylglycerol production. The mammalian PKD family consists of three isoforms, PKD1, PKD2, and PKD3; of these PKD1 and PKD2 contain PDZ-binding motifs at their carboxyl termini.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87a874bdb92bf83d6aab47ccd981376
https://doi.org/10.1074/jbc.m109.024547

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Biological Evaluation of a Secondary Metabolite, 9-O-methylfusarubin, from Fusarium oxysporum

Autor: Jeffrey D. Hugdahl, Erin L. Garcia, John D. Bauer, Horace G. Cutler, Diane F. Matesic, Stephen J. Cutler

Publikováno v: Medicinal Chemistry Research. 14:369-381

9-O-methylfusarubin was isolated from a novel source, Fusarion oxysporum, and evaluated for its phytotoxic and chlorotic inducing properties in plants as well as its potential as an antineoplastic agent. Etiolated wheat coleptiles were inhibited 100

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9056437d6105e906c1dac9bc4c0a781
https://doi.org/10.1007/s00044-006-0145-3

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PDZ interactions between PHLPP phosphatases and the NHERF scaffold

Autor: Alexandra C. Newton, Randy A. Hall, Maya T. Kunkel, Erin L. Garcia

Publikováno v: The FASEB Journal. 26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1328a57264b531ce8d5055f35895b01
https://doi.org/10.1096/fasebj.26.1_supplement.761.26

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Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)

Autor: Michael Leitges, Alan P. Fields, Lisa L. Gallegos, Verline Justilien, Erin L. Garcia, Audrey K. O’Neill, Randy A. Hall, Alexandra C. Newton

Publikováno v: The Journal of biological chemistry. 286(50)

Protein scaffolds maintain precision in kinase signaling by coordinating kinases with components of specific signaling pathways. Such spatial segregation is particularly important in allowing specificity of signaling mediated by the 10-member family

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ed477ddd28b021f549789aaaeeea2b
https://pubmed.ncbi.nlm.nih.gov/22027822

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Imaging PKC activity at MAGUK protein scaffolds

Autor: Lisa L. Gallegos, Erin L. Garcia, Randy A. Hall, Alexandra C. Newton

Publikováno v: The FASEB Journal. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2baf1be00ddc6212ae0e6442d5efe6f9
https://doi.org/10.1096/fasebj.22.1_supplement.1048.9

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Localized PKD activity at PDZ domain‐containing scaffolds

Autor: Erin L. Garcia, Maya T. Kunkel, Randy A. Hall, Alexandra C. Newton

Publikováno v: The FASEB Journal. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5905f91fef634b15d20d040232d2981a
https://doi.org/10.1096/fasebj.22.1_supplement.1048.13

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Inhibition of cytokinesis and akt phosphorylation by chaetoglobosin K in ras-transformed epithelial cells

Autor: Horace G. Cutler, Diane F. Matesic, Kimberly N. Villio, Stacey Folse, Erin L. Garcia, Stephen J. Cutler

Publikováno v: Cancer chemotherapy and pharmacology. 57(6)

Purpose: Chaetoglobosin K (ChK), a bioactive natural product previously shown to have anti-tumor promoting activity in glial cells and growth inhibitory effects in ras-transformed fibroblasts, inhibited anchorage-dependent and anchorage-independent g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40d61bac86a03444cc29b49e604e751
https://pubmed.ncbi.nlm.nih.gov/16254733

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A C-terminal class I PDZ binding motif of EspI/NleA modulates the virulence of attaching and effacing Escherichia coli and Citrobacter rodentium

Autor: Michelle L Kelly, Roy M. Robins-Browne, Sau Fung Lee, Adrian Dale McAlister, Erin L. Garcia, Shelley Narelle Luck, Elizabeth L. Hartland, Randy A. Hall, Gad Frankel

Publikováno v: Cellular Microbiology. :071103031556003

Enteropathogenic Escherichia coli induces characteristic attaching-effacing (A/E) lesions on the intestinal mucosa during infection. The locus of enterocyte effacement is essential for A/E lesion formation and encodes a type III secretion system that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2726cffe19191354a1dbfe022a7817f0
https://doi.org/10.1111/j.1462-5822.2007.01065.x

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