Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Erin L Wuebben"'
Autor:
Jesse L Cox, Phillip J Wilder, Joshua M Gilmore, Erin L Wuebben, Michael P Washburn, Angie Rizzino
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62857 (2013)
Medulloblastomas and glioblastomas, the most common primary brain tumors in children and adults, respectively, are extremely difficult to treat. Efforts to identify novel proteins essential for the growth of these tumors may help to further our under
Externí odkaz:
https://doaj.org/article/6da7a91251a74f32a76a175fcba343c5
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76345 (2013)
The self-renewal and pluripotency of embryonic stem cells (ESC) is regulated by a highly integrated network of essential transcription factors, which includes Sox2. Previous studies have shown that elevating Sox2 on its own in mouse ESC induces diffe
Externí odkaz:
https://doaj.org/article/c5e3728f5cda4c7481919ebfe05e15cd
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34827 (2012)
Recent studies have shown that the RNA binding protein Musashi 2 (Msi2) plays important roles during development. Msi2 has also been shown to be elevated in several leukemias and its elevated expression has been linked with poorer prognosis in these
Externí odkaz:
https://doaj.org/article/7579e2ea946c4465838ce2e7f30cef43
Autor:
Phillip J. Wilder, Don W. Coulter, Ethan P. Metz, Jesse L. Cox, Angie Rizzino, Kaustubh Datta, Erin L. Wuebben
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Background Quiescent tumor cells pose a major clinical challenge due to their ability to resist conventional chemotherapies and to drive tumor recurrence. Understanding the molecular mechanisms that promote quiescence of tumor cells could help identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6871dd3f8fa83ccd323ebee98db33e
https://pubmed.ncbi.nlm.nih.gov/32998722
https://pubmed.ncbi.nlm.nih.gov/32998722
Autor:
Angie Rizzino, Erin L. Wuebben
Publikováno v:
Oncotarget
// Erin L. Wuebben 1 and Angie Rizzino 1,2 1 Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA 2 Department of Biochemistry and Molecular Biology, University of Nebraska Medical C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0b184ee80e3255fb0d2c445a2959a1
https://pubmed.ncbi.nlm.nih.gov/28388544
https://pubmed.ncbi.nlm.nih.gov/28388544
Autor:
Erin L. Wuebben, Angie Rizzino, Phillip J. Wilder, Thomas C. Caffrey, Michael A. Hollingsworth, Jesse L. Cox, James A. Grunkemeyer
Publikováno v:
Oncotarget
Pancreatic ductal adenocarcinoma (PDAC) is a highly deadly malignancy. Expression of the stem cell transcription factor SOX2 increases during progression of PDAC. Knockdown of SOX2 in PDAC cell lines decreases growth in vitro; whereas, stable overexp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17d6281699489bb3681a46f7bd5680e
https://pubmed.ncbi.nlm.nih.gov/27145457
https://pubmed.ncbi.nlm.nih.gov/27145457
Autor:
Angie Rizzino, Erin L. Wuebben
Publikováno v:
Biochimica et biophysica acta. 1859(6)
Considerable progress has been made in understanding the roles of Sox2 and Oct4 in embryonic stem cells and mammalian embryogenesis. Specifically, significant progress has been made in answering three questions about the functions of Sox2 and Oct4, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9deb08312b6e509af4d6ad915adfdc83
https://pubmed.ncbi.nlm.nih.gov/26992828
https://pubmed.ncbi.nlm.nih.gov/26992828
Autor:
Jesse L. Cox, Michael A. Hollingsworth, Erin L. Wuebben, Angie Rizzino, Phillip J. Wilder, Michel M. Ouellette
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and deadly malignancies. Recently, the deubiquitinating protease USP9X has been shown to behave as an oncogene in a number of neoplasms, including those of breast, brain, colon, es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1512bdd910290488abed995788a86c80
https://europepmc.org/articles/PMC4119071/
https://europepmc.org/articles/PMC4119071/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e76345 (2013)
PLoS ONE, Vol 8, Iss 10, p e76345 (2013)
The self-renewal and pluripotency of embryonic stem cells (ESC) is regulated by a highly integrated network of essential transcription factors, which includes Sox2. Previous studies have shown that elevating Sox2 on its own in mouse ESC induces diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d911a5ca9bff51c4cdeae412276d1972
https://pubmed.ncbi.nlm.nih.gov/24116102
https://pubmed.ncbi.nlm.nih.gov/24116102
Publikováno v:
Cancer Research. 76:LB-280
Pancreatic ductal adenocarcinoma (PDAC) is a highly deadly cancer. The transcription factor SOX2 is expressed in ∼20 different cancers, and implicated in chemoresistance in many of these tumors. SOX2 increases as PDAC progresses to advanced stages.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe1a07bdffbb0426cb46f47440f812b4
https://doi.org/10.1158/1538-7445.am2016-lb-280
https://doi.org/10.1158/1538-7445.am2016-lb-280