Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Erin L Filbert"'
Autor:
Li Zhang, Lawrence Fong, Andrew H Ko, Brandon Chen, Alexander Cheung, Alec Starzinski, Hai Yang, Tony Li, Bridget P Keenan, Maira Soto, Erin L Filbert, Stephanie Starzinski, Marissa Gin, Phi Le, Brandon Bol, Frank J Hsu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d6f0d9b6024c4f07aadb89a3523af07b
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57137 (2013)
The mammalian target of rapamycin (mTOR) kinase is a critical regulator of the differentiation of helper and regulatory CD4+ T cells, as well as memory CD8+ T cells. In this study, we investigated the role of the ERK signaling pathway in regulating m
Externí odkaz:
https://doaj.org/article/c3702ac42b9c4f089e6d7b72830d1945
Publikováno v:
Cancer Immunology, Immunotherapy
Targeting CD40 with agonist antibodies is a promising approach to cancer immunotherapy. CD40 acts as a master regulator of immunity by mobilizing multiple arms of the immune system to initiate highly effective CD8 + T-cell-mediated responses against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea7b6ee4a942116039408133fb11db1
http://europepmc.org/articles/PMC8195934
http://europepmc.org/articles/PMC8195934
Autor:
Maira Soto, Erin L Filbert, Hai Yang, Li Zhang, Stephanie Starzinski, Alec Starzinski, Alexander Cheung, Tony Li, Frank J. Hsu, Andrew H. Ko, Lawrence Fong, Bridget P Keenan
Publikováno v:
Journal of Clinical Oncology. 41:450-450
450 Background: Neoadjuvant chemoradiation (CRT) followed by surgical resection is standard of care for patients with locally advanced esophageal/gastroesophageal junction (E/GEJ) cancer. A pathologic complete response (pCR) at surgery is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77cb2880ce420f22df1d043a98c7075a
https://doi.org/10.1200/jco.2023.41.4_suppl.450
https://doi.org/10.1200/jco.2023.41.4_suppl.450
Autor:
Montaser Shaheen, Lynn M. Schuchter, Delvys Rodriguez-Abreu, Erin L. Filbert, Maria Gonzalez-Cao, Apar Kishor Ganti, Ralph J. Hauke, Enriqueta Felip, Nicholas Iannotti, Ana Arance, Sarah A. Weiss, Harriet M. Kluger, Valentina Boni, Mario Sznol, Alfonso Berrocal, Miguel-Ángel Berciano-Guerrero, Gerald P. Linette
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundA significant number of melanoma patients treated with anti-PD-1 alone or in combination with anti-CTLA-4 have transient or no response to treatment. Sotigalimab is a CD40 agonist antibody with unique epitope specificity and Fc receptor bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2113b83663c0d15006bc607da094b55b
https://doaj.org/article/486cee47556042ac976f547e0220656d
https://doaj.org/article/486cee47556042ac976f547e0220656d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background A key barrier to effective immunotherapy for cancer is the immunosuppressive tumor microenvironment (TME) characterized by infiltrating regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSC). While depletion of immune-suppr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed12b8cee5ea53d893d24c0d6ab826c2
https://doaj.org/article/1e2364dd92574f138ccac85e1fb4d27d
https://doaj.org/article/1e2364dd92574f138ccac85e1fb4d27d
Autor:
Erin L. Filbert, Christine Tan, Frances R. Bahjat, Swati Jalgaonkar, George Huang, Sushma Krishnan, Xiaodong Yang, Ryan Alvarado, Minu K. Srivastava
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Therapeutically targeting tumor myeloid cells has emerged as a novel and complementary strategy to existing cancer immunotherapy approaches. The interaction of tumor expressed CD47 with SIRP alpha (signal regulatory protein-alphaa, SIRPA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e12e9de10a0485e30eb8869a90de60
https://doaj.org/article/a65205f318ff458d9a4a9c8ed8f6047c
https://doaj.org/article/a65205f318ff458d9a4a9c8ed8f6047c
Publikováno v:
Cancer Research. 81:LB175-LB175
A key barrier to effective immunotherapy for cancer is the immunosuppressive tumor microenvironment (TME) characterized by infiltrating regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSC). While depletion of immune-suppressive cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71b18888628a1098881fd37e3d17012a
https://doi.org/10.1158/1538-7445.am2021-lb175
https://doi.org/10.1158/1538-7445.am2021-lb175
Autor:
Ryan Alvarado, Christine Tan, George Huang, Erin L. Filbert, Minu K. Srivastava, Xiaodong Yang, Sushma Krishnan, Swati Jalgaonkar, Frances R. Bahjat
Publikováno v:
Cancer Research. 81:LB177-LB177
Therapeutically targeting tumor myeloid cells has emerged as a complementary strategy to existing cancer immunotherapy approaches. The interaction of tumor-expressed CD47 with SIRPα (Signal Regulatory Protein-α, SIRPA) on macrophages, dendritic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f21b932ee382fa3f1e53d464a6fa8571
https://doi.org/10.1158/1538-7445.am2021-lb177
https://doi.org/10.1158/1538-7445.am2021-lb177
Publikováno v:
The Journal of Immunology. 188:5421-5427
Polarization of T cells involves reorientation of the microtubule organizing center (MTOC). Because activated ERK is localized at the immunological synapse, we investigated its role by showing that ERK activation is important for MTOC polarization. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031a0e2d29fbe190fcd3c038f4585b04
https://doi.org/10.4049/jimmunol.1200242
https://doi.org/10.4049/jimmunol.1200242