Full activation of thermogenesis in brown adipocytes requires Basigin action

Autor: Kaja Rupar, Marie S. Isidor, Lidia Argemi‐Muntadas, Marina Agueda‐Oyarzabal, Kaja Plucińska, Erin L. Brown, Matthias Mattanovich, Simone Bossi, Marco Tozzi, David Tandio, Patricia S. S. Petersen, Tora I. Henriksen, Kajetan Trošt, Jacob B. Hansen, Zachary Gerhart‐Hines, Søren Nielsen, Thomas Moritz, Brice Emanuelli

Publikováno v: Rupar, K, Isidor, M S, Argemi-Muntadas, L, Agueda-Oyarzabal, M, Plucińska, K, Brown, E L, Mattanovich, M, Bossi, S, Tozzi, M, Tandio, D, Petersen, P S S, Henriksen, T I, Trošt, K, Hansen, J B, Gerhart-Hines, Z, Nielsen, S, Moritz, T & Emanuelli, B 2023, ' Full activation of thermogenesis in brown adipocytes requires Basigin action ', F E B S Journal, vol. 290, no. 10, pp. 2673-2691 . https://doi.org/10.1111/febs.16716

Exploring mechanisms responsible for brown adipose tissue's (BAT) high metabolic activity is crucial to exploit its energy dissipating ability for therapeutic purposes. Basigin (Bsg), a multifunctional highly glycosylated transmembrane protein - was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99624d583a33cf2bbd7d553b7ae8f732
https://doi.org/10.1111/febs.16716

Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation

Autor: Erin L. Brown, Bethany C. Hazen, Elodie Eury, Jean-Sébastien Wattez, Marin L. Gantner, Verena Albert, Sarah Chau, Manuel Sanchez-Alavez, Bruno Conti, Anastasia Kralli

Publikováno v: iScience, Vol 2, Iss , Pp 221-237 (2018)

Summary: Adrenergic stimulation of brown adipose tissue (BAT) induces acute and long-term responses. The acute adrenergic response activates thermogenesis by uncoupling oxidative phosphorylation and enabling increased substrate oxidation. Long-term,

Externí odkaz: https://doaj.org/article/24d87279e8a148f7a6c2a7388b0e7c79

PGC-1α and PGC-1β Increase Protein Synthesis via ERRα in C2C12 Myotubes

Autor: Erin L. Brown, Victoria C. Foletta, Craig R. Wright, Patricio V. Sepulveda, Nicky Konstantopoulos, Andrew Sanigorski, Paul Della Gatta, David Cameron-Smith, Anastasia Kralli, Aaron P. Russell

Publikováno v: Frontiers in Physiology, Vol 9 (2018)

The transcriptional coactivators peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) and PGC-1β are positive regulators of skeletal muscle mass and energy metabolism; however, whether they influence muscle growth and metabolic ad

Externí odkaz: https://doaj.org/article/d3b201bbedd745bf8ccf4940a20531a6

Author response for 'Full activation of thermogenesis in brown adipocytes requires Basigin action'

Autor: null Kaja Rupar, null Marie S. Isidor, null Lidia Argemi‐Muntadas, null Marina Agueda‐Oyarzabal, null Kaja Plucińska, null Erin L. Brown, null Matthias Mattanovich, null Simone Bossi, null Marco Tozzi, null David Tandio, null Patricia S. S. Petersen, null Tora I. Henriksen, null Kajetan Trošt, null Jacob B. Hansen, null Zachary Gerhart‐Hines, null Søren Nielsen, null Thomas Moritz, null Brice Emanuelli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae91cad4a66a99e9fd066d0c147ff499
https://doi.org/10.1111/febs.16716/v2/response1

Robust alignment of single-cell and spatial transcriptomes with CytoSPACE

Autor: Milad R. Vahid, Erin L. Brown, Chloé B. Steen, Minji Kang, Andrew J. Gentles, Aaron M. Newman

Recent studies have emphasized the importance of single-cell spatial biology, yet available assays for spatial transcriptomics have limited gene recovery or low spatial resolution. Here we introduce CytoSPACE, a method for aligning single-cell and sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4d4dde87b276cee25b8a6c6b5ce33f0
https://doi.org/10.1101/2022.05.20.488356