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pro vyhledávání: '"Erin K. Rawstron"'
Autor:
Emilyn U. Alejandro, K. J. Jacob, Kamila S. Gwiazda, James D. Johnson, Farnaz Taghizadeh, Tatyana B. Kalynyak, Erin K. Rawstron
Publikováno v:
Endocrinology. 151:502-512
Insulin enhances the proliferation and survival of pancreatic beta-cells, but its mechanisms remain unclear. We hypothesized that Raf-1, a kinase upstream of both ERK and Bad, might be a critical target of insulin in beta-cells. To test this hypothes