Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Erin K. Molloy"'
Publikováno v:
Algorithms for Molecular Biology, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract The last decade of phylogenetics has seen the development of many methods that leverage constraints plus dynamic programming. The goal of this algorithmic technique is to produce a phylogeny that is optimal with respect to some objective fun
Externí odkaz:
https://doaj.org/article/44e6e82cfe8b4e33a1645e1d2397aaa1
Autor:
Yunheng Han, Erin K. Molloy
Publikováno v:
Algorithms for Molecular Biology, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Cancer progression and treatment can be informed by reconstructing its evolutionary history from tumor cells. Although many methods exist to estimate evolutionary trees (called phylogenies) from molecular sequences, traditional approaches as
Externí odkaz:
https://doaj.org/article/b383dd9fd4f24707be3c481ec7fd48e7
Autor:
Seth Commichaux, Hugh Rand, Kiran Javkar, Erin K. Molloy, James B. Pettengill, Arthur Pightling, Maria Hoffmann, Mihai Pop, Victor Jayeola, Steven Foley, Yan Luo
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background The Salmonella enterica serovar Newport red onion outbreak of 2020 was the largest foodborne outbreak of Salmonella in over a decade. The epidemiological investigation suggested two farms as the likely source of contamination. How
Externí odkaz:
https://doaj.org/article/ca72768b89244be3bfd51dc49a272706
Publikováno v:
Algorithms for Molecular Biology, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract One of the Grand Challenges in Science is the construction of the Tree of Life, an evolutionary tree containing several million species, spanning all life on earth. However, the construction of the Tree of Life is enormously computationally
Externí odkaz:
https://doaj.org/article/7cbd274d63f64394a09dfa032a05c206
Publikováno v:
Algorithms for Molecular Biology, Vol 15, Iss 1, Pp 1-18 (2020)
Abstract Motivation Estimated gene trees are often inaccurate, due to insufficient phylogenetic signal in the single gene alignment, among other causes. Gene tree correction aims to improve the accuracy of an estimated gene tree by using computationa
Externí odkaz:
https://doaj.org/article/5573d19fb7344708a2e74c2d0ddb19ee
Autor:
Erin K. Molloy, Tandy Warnow
Publikováno v:
Algorithms for Molecular Biology, Vol 14, Iss 1, Pp 1-17 (2019)
Abstract Background Divide-and-conquer methods, which divide the species set into overlapping subsets, construct a tree on each subset, and then combine the subset trees using a supertree method, provide a key algorithmic framework for boosting the s
Externí odkaz:
https://doaj.org/article/176785c43be04072beeba7f100b60370
Publikováno v:
BMC Genomics, Vol 19, Iss S5, Pp 1-22 (2018)
Abstract Background Estimation of species trees from multiple genes is complicated by processes such as incomplete lineage sorting, gene duplication and loss, and horizontal gene transfer, that result in gene trees that differ from each other and fro
Externí odkaz:
https://doaj.org/article/0492987b64844f5798a6b8ee4e631f83
Publikováno v:
Algorithms for Molecular Biology, Vol 13, Iss 1, Pp 1-18 (2018)
Abstract Background For a combination of reasons (including data generation protocols, approaches to taxon and gene sampling, and gene birth and loss), estimated gene trees are often incomplete, meaning that they do not contain all of the species of
Externí odkaz:
https://doaj.org/article/dd4fb2459f144549a27142ce5d1a1684
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-2 (2020)
After publication of [1], the authors were informed by John A. Rhodes of a counterexample to Theorem 11 of [1].
Externí odkaz:
https://doaj.org/article/f5cd5f6d7fa54ce1afcdca4c0557a4c3
Publikováno v:
American journal of human genetics, vol 109, iss 4
Inferring the structure of human populations from genetic variation data is a key task in population and medical genomic studies. Although a number of methods for population structure inference have been proposed, current methods are impractical to r