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pro vyhledávání: '"Erin K. Borchardt"'
Autor:
Rita M. Meganck, Erin K. Borchardt, Ruth M. Castellanos Rivera, Miranda L. Scalabrino, Jeremy E. Wilusz, William F. Marzluff, Aravind Asokan
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 89-98 (2018)
Circular RNAs (circRNAs) are long-lived, covalently closed RNAs that are abundantly expressed and evolutionarily conserved across eukaryotes. Possible functions ranging from microRNA (miRNA) and RNA binding protein sponges to regulators of transcript
Externí odkaz:
https://doaj.org/article/4b05f58b76984d22b571558cdd5de463
Publikováno v:
Annu Rev Genet
Recent advances in pseudouridine detection reveal a complex pseudouridine landscape that includes messenger RNA and diverse classes of noncoding RNA in human cells. The known molecular functions of pseudouridine, which include stabilizing RNA conform
Autor:
Erin K. Borchardt, Jeremy E. Wilusz, William F. Marzluff, Ruth M. Castellanos Rivera, Miranda L. Scalabrino, Aravind Asokan, Rita M. Meganck
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss, Pp 89-98 (2018)
Circular RNAs (circRNAs) are long-lived, covalently closed RNAs that are abundantly expressed and evolutionarily conserved across eukaryotes. Possible functions ranging from microRNA (miRNA) and RNA binding protein sponges to regulators of transcript
Publikováno v:
Journal of the American Chemical Society. 137:5642-5645
The CRISPR/Cas9 system has emerged as an important tool in biomedical research for a wide range of applications, with significant potential for genome engineering and gene therapy. In order to achieve conditional control of the CRISPR/Cas9 system, a
Autor:
Nathaniel J. Moorman, Erin K. Borchardt, Silvia B. V. Ramos, Rita M. Meganck, Christopher B. Ball, William F. Marzluff, Heather A. Vincent, Aravind Asokan
Circular RNAs (circRNAs) are highly stable, covalently closed RNAs that are regulated in a spatiotemporal manner and whose functions are largely unknown. These molecules have the potential to be incorporated into engineered systems with broad technol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6cc9eeb50bdf92302f9d9ef67941c4
Publikováno v:
Journal of Bacteriology. 195:5174-5185
The Gram-positive obligate anaerobe Clostridium difficile causes potentially fatal intestinal diseases. How this organism regulates virulence gene expression is poorly understood. In many bacterial species, the second messenger cyclic di-GMP (c-di-GM
Autor:
William F. Marzluff, Aravind Asokan, Leonidas A. Vandoros, Michael Huang, Patrick E. Lackey, Erin K. Borchardt
The bacterial CRISPR endoribonuclease Csy4 has recently been described as a potential RNA processing tool. Csy4 recognizes substrate RNA through a specific 28-nt hairpin sequence and cleaves at the 3′ end of the stem. To further explore applicabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c376047b98e61cb3c70998889eab97eb