Probabilistic genotyping of single cell replicates from complex DNA mixtures recovers higher contributor LRs than standard analysis

Autor: Jack Ballantyne, Kaitlin Huffman, Erin K. Hanson

Publikováno v: Sciencejustice : journal of the Forensic Science Society. 62(2)

DNA mixtures are a common source of crime scene evidence and are often one of the more difficult sources of biological evidence to interpret. With the implementation of probabilistic genotyping (PG), mixture analysis has been revolutionized allowing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef21757a53371a2056291b09949d73b
https://pubmed.ncbi.nlm.nih.gov/35277229

Rapid and inexpensive body fluid identification by RNA profiling-based multiplex High Resolution Melt (HRM) analysis [v1; ref status: indexed, http://f1000r.es/2hj]

Autor: Erin K. Hanson, Jack Ballantyne

Publikováno v: F1000Research, Vol 2 (2013)

Positive identification of the nature of biological material present on evidentiary items can be crucial for understanding the circumstances surrounding a crime. However, traditional protein-based methods do not permit the identification of all body

Externí odkaz: https://doaj.org/article/b9de15c6c2034dc7af3ac9ae589c30a7

Recovery of single source DNA profiles from mixtures by direct single cell subsampling and simplified micromanipulation

Autor: Jack Ballantyne, Erin K. Hanson, Kaitlin Huffman

Publikováno v: Sciencejustice : journal of the Forensic Science Society. 61(1)

Deconvolution of forensic DNA mixtures into their individual component DNA (geno)types is of great investigative value, though often complex and difficult. Two-person mixtures comprising a major and minor contributor are often easily interpreted alth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99dd46f49a6c18ddc947b57a78630bbc
https://pubmed.ncbi.nlm.nih.gov/33357824

Messenger RNA biomarker signatures for forensic body fluid identification revealed by targeted RNA sequencing

Autor: Sabrina Ingold, Jack Ballantyne, Erin K. Hanson, Cordula Haas

Publikováno v: Forensic Science International: Genetics. 34:206-221

The recovery of a DNA profile from the perpetrator or victim in criminal investigations can provide valuable ‘source level’ information for investigators. However, a DNA profile does not reveal the circumstances by which biological material was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e5383f1d6c6b52fe50b3b5bdc09047
https://doi.org/10.1016/j.fsigen.2018.02.020

Body fluid identification using a targeted mRNA massively parallel sequencing approach - results of a EUROFORGEN/EDNAP collaborative exercise

Autor: F.-X. Laurent, M. van den Berge, Guro Dørum, A.D. Roeder, Cordula Haas, Andrea Berti, M. Trautmann, Theresa E. Gross, Denise Syndercombe-Court, Ana Mosquera-Miguel, P. Brito, Athina Vidaki, E. N. Hanssen, Erin K. Hanson, Ewelina Pośpiech, Marie-Louise Kampmann, Niels Morling, Katherine Butler Gettings, K.J. van der Gaag, Maria João Porto, Jack Ballantyne, Manfred Kayser, K. Schulze Johann, J. Vannier, Carolyn R. Steffen, Federica Giangasparo, P. Elsmore, Sabrina Ingold, V. Verdoliva, Walther Parson, Christopher Phillips, S. Hansen, Catarina Xavier, Wojciech Branicki, Peter M. Schneider

Publikováno v: Ingold, S, Dørum, G, Hanson, E, Berti, A, Branicki, W, Brito, P, Elsmore, P, Gettings, K B, Giangasparo, F, Gross, T E, Hansen, S, Hanssen, E N, Kampmann, M-L, Kayser, M, Laurent, F-X, Morling, N, Mosquera-Miguel, A, Parson, W, Phillips, C, Porto, M J, Pośpiech, E, Roeder, A D, Schneider, P M, Johann, K S, Steffen, C R, Syndercombe-Court, D, Trautmann, M, van den Berge, M, van den Gaag, K J, Vannier, J, Verdoliva, V, Vidaki, A, Xavier, C & Ballantyne, J 2018, ' Body fluid identification using a targeted mRNA massively parallel sequencing approach – results of a EUROFORGEN/EDNAP collaborative exercise ', Forensic Science International-Genetics . https://doi.org/10.1016/j.fsigen.2018.01.002
Forensic Science International: Genetics, 34, 105-115. Elsevier Ireland Ltd

In a previous study we presented an assay for targeted mRNA sequencing for the identification of human body fluids, optimised for the Illumina MiSeq/FGx MPS platform. This assay, together with an additional in-house designed assay for the Ion Torrent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e483f9cf55d093d770c8dde11f8ebae
https://pure.eur.nl/en/publications/71c74d70-7ee4-4400-87b8-eedd32257e64