PD-1 blockade for diffuse large B-cell lymphoma after autologous stem cell transplantation

Autor: Matthew J. Frigault, Philippe Armand, Robert A. Redd, Erin Jeter, Reid W. Merryman, Kimberly C. Coleman, Alex F. Herrera, Parastoo Dahi, Yago Nieto, Ann S. LaCasce, David C. Fisher, Samuel Y. Ng, Oreife O. Odejide, Arnold S. Freedman, Austin I. Kim, Jennifer L. Crombie, Caron A. Jacobson, Eric D. Jacobsen, Jeffrey L. Wong, Jad Bsat, Sanjay S. Patel, Jerome Ritz, Scott J. Rodig, Margaret A. Shipp, Yi-Bin Chen, Robin M. Joyce

Publikováno v: Blood Advances, Vol 4, Iss 1, Pp 122-126 (2020)

Abstract: Disease relapse remains the leading cause of failure after autologous stem cell transplantation (ASCT) for patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL). We conducted a phase 2, multicenter, single-arm study of

Externí odkaz: https://doaj.org/article/6dcead3a5e7b4235ab3757f5129bfa75

Prognostic value of minimal residual disease among patients with classical Hodgkin lymphoma undergoing autologous stem cell transplantation

Autor: Eleanor Taranto, Robert Redd, Erin Jeter, Kristin McHugh, Jennifer L. Crombie, David C. Fisher, Eric Jacobsen, Caron A. Jacobson, Austin I. Kim, Ann S. LaCasce, Oreofe O. Odejide, Parastoo B. Dahi, Yago Nieto, Robin M. Joyce, Yi-Bin Chen, Kimberley-Jane C. Bonjoc, Ammar Chaudhry, Alex F. Herrera, Philippe Armand, Reid W. Merryman

Publikováno v: Leukemialymphoma. 63(12)

Improved biomarkers are needed to guide patient selection for autologous stem cell transplantation (ASCT) and post-ASCT maintenance therapies in relapsed/refractory classical Hodgkin lymphoma (cHL). To assess the prognostic value of minimal residual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9be88d5da6cadd5373287841b222c67
https://pubmed.ncbi.nlm.nih.gov/35938581

Poor outcome of CHOEP induction followed by gemcitabine/busulfan/melphalan high-dose therapy and stem cell rescue for patients with newly diagnosed peripheral T-cell lymphoma

Autor: Eric D, Jacobsen, Haesook T, Kim, Erin, Jeter, Caron, Jacobson, David C, Fisher, Philippe, Armand

Publikováno v: Bone marrow transplantation. 57(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42af149e357d4dd377464dc08dbb9e5c
https://pubmed.ncbi.nlm.nih.gov/35996021

Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma

Autor: Azra H. Ligon, Christopher D.M. Fletcher, Eric D. Jacobsen, Evisa Gjini, Michael H. Rosenthal, Caron A. Jacobson, Scott J. Rodig, Scott B. Lovitch, Jeffrey J. Ishizuka, Jie Xu, F. Stephen Hodi, Ann S. LaCasce, Bjoern Chapuy, Philippe Armand, Margaretha G.M. Roemer, Gabriel K. Griffin, Alyssa Kelley, Jason L. Weirather, Daniel Gusenleitner, Austin I. Kim, Kyle Wright, Margaret A. Shipp, Benjamin J. Chen, Pei Hsuan Chen, Mikel Lipschitz, Erin Jeter, Jeremy S. Abramson, Gordon J. Freeman, Aliyah R. Sohani, Christine Pak, Donna Neuberg

Publikováno v: Griffin, G K, Weirather, J L, Roemer, M G M, Lipschitz, M, Kelley, A, Chen, P-H, Gusenleitner, D, Jeter, E, Pak, C, Gjini, E, Chapuy, B, Rosenthal, M H, Xu, J, Chen, B J, Sohani, A R, Lovitch, S B, Abramson, J S, Ishizuka, J J, Kim, A I, Jacobson, C A, LaCasce, A S, Fletcher, C D, Neuberg, D, Freeman, G J, Hodi, F S, Wright, K, Ligon, A H, Jacobsen, E D, Armand, P, Shipp, M A & Rodig, S J 2021, ' Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma ', Blood, vol. 137, no. 10, pp. 1353-1364 . https://doi.org/10.1182/blood.2020006464
Blood, 137(10), 1353-1364. American Society of Hematology

T-cell/histiocyte-rich large B-cell lymphoma (TCRLBCL) is an aggressive variant of diffuse large B-cell lymphoma (DLBCL) characterized by rare malignant B cells within a robust but ineffective immune cell infiltrate. The mechanistic basis of immune e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0c5b5b125bf3c129b5899ef2874a80
https://research.vumc.nl/en/publications/7a18c2f6-cb69-4cf9-830d-05bc16763cf4

Interim Positron Emission Tomography (iPET) Assessed Using Deauville Score for Patients with Follicular Lymphoma Receiving First-Line Chemoimmunotherapy

Autor: Patrizia Mondello, Jennifer R. Brown, Ann S. LaCasce, Heather A. Jacene, Oreofe O. Odejide, Gilles Salles, Caron A. Jacobson, Reid W. Merryman, Matthew Chase, Erin Jeter, Gulrayz Ahmed, Eleanor Taranto, David C. Fisher, Samuel Y. Ng, Philippe Armand, Austin I. Kim, Robert A. Redd, Matthew S. Davids, Eric D. Jacobsen, Jennifer L. Crombie, Andrew D. Zelenetz, Arnold S. Freedman, Benjamin L. Lampson, Gabriela Spilberg

Publikováno v: Blood. 136:37-38

Background: While most patients (pts) with follicular lymphoma (FL) have excellent outcomes with frontline chemoimmunotherapy (CIT), a subset of pts will experience early progression, which is associated with inferior survival. Earlier identification

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f8455963bd73e28b3818ce428ffc965
https://doi.org/10.1182/blood-2020-135919