Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Erin H. Plisch"'
Autor:
David J Gasper, Brandon Neldner, Erin H Plisch, Hani Rustom, Emily Carrow, Hirotaka Imai, Yoshihiro Kawaoka, M Suresh
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006064 (2016)
CD8+ cytotoxic T lymphocytes (CTLs) are critical for clearing many viral infections, and protective CTL memory can be induced by vaccination with attenuated viruses and vectors. Non-replicating vaccines are typically potentiated by the addition of ad
Externí odkaz:
https://doaj.org/article/6e097ea864b047ee89b23499725fc7ee
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002533 (2012)
CD8 T cell responses have three phases: expansion, contraction, and memory. Dynamic alterations in proliferation and apoptotic rates control CD8 T cell numbers at each phase, which in turn dictate the magnitude of CD8 T cell memory. Identification of
Externí odkaz:
https://doaj.org/article/2974419d1ebe472f9fcf2c67636d5ab9
Autor:
Yumi Nakayama, Erin H Plisch, Jeremy Sullivan, Chester Thomas, Charles J Czuprynski, Bryan R G Williams, M Suresh
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000966 (2010)
Type I interferons (IFNs) are known to mediate viral control, and also promote survival and expansion of virus-specific CD8+ T cells. However, it is unclear whether signaling cascades involved in eliciting these diverse cellular effects are also dist
Externí odkaz:
https://doaj.org/article/67966041c01049d29b0c04ea45a7eb6e
Autor:
Chad M. Vezina, Erin H. Plisch, M. Suresh, Laura L. Hernandez, Kimberly P. Keil, Vatsal Mehta, Helene M. Altmann, Jimena Laporta, Lisa L. Abler
Publikováno v:
Developmental Biology. 387:142-153
In prostate and other epithelial cancers, E-cadherin (CDH1) is downregulated inappropriately by DNA methylation to promote an invasive phenotype. Though cancer frequently involves a reawakening of developmental signaling pathways, whether DNA methyla
Autor:
Emily Carrow, Hirotaka Imai, Hani Rustom, M. Suresh, Brandon Neldner, Yoshihiro Kawaoka, Erin H. Plisch, David J. Gasper
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 12, p e1006064 (2016)
PLoS Pathogens, Vol 12, Iss 12, p e1006064 (2016)
CD8+ cytotoxic T lymphocytes (CTLs) are critical for clearing many viral infections, and protective CTL memory can be induced by vaccination with attenuated viruses and vectors. Non-replicating vaccines are typically potentiated by the addition of ad
Publikováno v:
Journal of Virology. 86:9025-9034
Chronic infections with viruses such as hepatitis B virus, hepatitis C virus, and HIV constitute a major global public health problem. Studies of chronic viral infections in humans and mice show that persistent antigenic stimulation induces dysregula
Autor:
Erin H. Plisch, Kwan Yong Choi, Anna Jatzek, Eui Ho Kim, M. Suresh, Melba Marie Tejera, Jeremy A. Sullivan
Publikováno v:
The Journal of Immunology. 188:4305-4314
During a T cell response, the effector CTL pool contains two cellular subsets: short-lived effector cells (SLECs), a majority of which are destined for apoptosis, and the memory precursor effector cells, which differentiate into memory cells. Underst
Autor:
Erin H. Plisch, Zhengling Hao, Susan L. Schaefer, Jennifer L. Kelly, M. Suresh, Peter Muir, Paul A. Manley, Daniel A. Heinrich, Kavita Tewari, Sarah J. Marvel, Anju Singh
Publikováno v:
Veterinary Surgery. 40:753-761
OBJECTIVE To evaluate lymphocyte populations in stifle synovium and synovial fluid of dogs with degenerative cranial cruciate ligament rupture (CCLR). STUDY DESIGN Prospective clinical study. ANIMALS Dogs (n=25) with stifle arthritis and CCLR, 7 dogs
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(3)
Variants of the Bach2 gene are linked to vitiligo, celiac disease, and type 1 diabetes, but the underlying immunological mechanisms are unknown. In this study, we demonstrate that Bach2 plays crucial roles in maintaining T cell quiescence and governi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(1)
During a T cell response, naive CD8 T cells differentiate into effector cells. Subsequently, a subset of effector cells termed memory precursor effector cells further differentiates into functionally mature memory CD8 T cells. The transcriptional net