Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Erin E. Dymek"'
Autor:
Gang Fu, Zhiguo Shang, Erin E. Dymek, Elizabeth F. Smith, Kangkang Song, Daniela Nicastro, Nhan Phan, George B. Witman, Yuqing Hou, Lei Zhao
Publikováno v:
The Journal of Cell Biology
Fu et al. use a WT versus mutant comparison and cryo-electron tomography of Chlamydomonas flagella to identify central apparatus (CA) subunits and visualize their location in the native 3D CA structure. This study provides a better understanding of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974a0f517d35fcf107fb9435f80c7a79
https://doi.org/10.1083/jcb.201906006
https://doi.org/10.1083/jcb.201906006
Publikováno v:
Molecular Biology of the Cell
We previously demonstrated that PACRG plays a role in regulating dynein-driven microtubule sliding in motile cilia. To expand our understanding of the role of PACRG in ciliary assembly and motility, we used a combination of functional and structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b031f5d9844ece2f4749ad5dc8ddfe7
https://doi.org/10.1091/mbc.e19-01-0063
https://doi.org/10.1091/mbc.e19-01-0063
Autor:
Eileen T. O'Toole, Catherine A. Perrone, Daniela Nicastro, Kristyn VanderWaal Mills, Raqual Bower, Katherine Augspurger, Mary E. Porter, Erin E. Dymek, Jianfeng Lin, Gang Fu, Thuc Vy Le, Elizabeth F. Smith, Douglas Tritschler
Publikováno v:
Molecular Biology of the Cell
Ciliary motility depends on both the precise spatial organization of multiple dynein motors within the 96 nm axonemal repeat, and highly coordinated interactions between different dyneins and regulatory complexes located at the base of the radial spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4410bf44a21d9e1139a709355fa9a6
Publikováno v:
Cytoskeleton. 73:703-711
The complex waveforms characteristic of motile eukaryotic cilia and flagella are produced by the temporally and spatially regulated action of multiple dynein subforms generating sliding between subsets of axonemal microtubules. Multiple protein compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d788758395289f5af65fd1bd11861af1
https://doi.org/10.1002/cm.21340
https://doi.org/10.1002/cm.21340
Autor:
Ewa Joachimiak, Daniela Nicastro, Paulina Urbanska, Lea M. Alford, Winfield S. Sale, Jacek Gaertig, Todd M. Hennessey, Dorota Wloga, Kangkang Song, Erin E. Dymek, Krishna Kumar Vasudevan, Elizabeth F. Smith, William L. Dentler
Publikováno v:
Molecular Biology of the Cell
Radial spokes are conserved macromolecular complexes that are essential for ciliary motility. Little is known about the assembly and functions of the three individual radial spokes, RS1, RS2, and RS3. In Tetrahymena, a conserved ciliary protein, FAP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f12bb90c2a8d20a95bd1eb151a90f25
https://doi.org/10.1091/mbc.e14-11-1506
https://doi.org/10.1091/mbc.e14-11-1506
Publikováno v:
Molecular Biology of the Cell
This study reveals the 3D structure of the CSC and its connections to three major axonemal complexes involved in dynein regulation, including the distal radial spoke and the nexin-DRC. The findings corroborate radial spoke heterogeneity and suggest a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8419ec4047aab3b81d5732751d613ba
https://doi.org/10.1091/mbc.e12-05-0357
https://doi.org/10.1091/mbc.e12-05-0357
Publikováno v:
Journal of Cell Science. 119:3107-3116
Kinesin-like calmodulin-binding protein, KCBP, is a novel member of the C-kinesin superfamily first discovered in flowering plants. This minus-end-directed kinesin exhibits Ca2+-calmodulin-sensitive motor activity in vitro and has been implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387b8e0c34c933cd7fc96a453d63fb6a
https://doi.org/10.1242/jcs.03028
https://doi.org/10.1242/jcs.03028
Publikováno v:
Molecular Biology of the Cell
Structural and functional analyses of artificial micro RNA (amiRNA) mutants reveal that the CSC plays a role not only in generating wild-type motility, but also in assembly of at least a subset of radial spokes. This study also produced the unexpecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf247964c36143d820679ce2eab3dc2
https://pubmed.ncbi.nlm.nih.gov/21613541
https://pubmed.ncbi.nlm.nih.gov/21613541
Autor:
Erin E. Dymek, Elizabeth F. Smith
Publikováno v:
The Journal of Cell Biology
For virtually all cilia and eukaryotic flagella, the second messengers calcium and cyclic adenosine monophosphate are implicated in modulating dynein- driven microtubule sliding to regulate beating. Calmodulin (CaM) localizes to the axoneme and is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb7e8dc2a7228392db4fa730e01ab5f
https://pubmed.ncbi.nlm.nih.gov/17967944
https://pubmed.ncbi.nlm.nih.gov/17967944
Publikováno v:
Journal of cell science. 118(Pt 20)
Studies of flagellar motility in Chlamydomonas mutants lacking specific central apparatus components have supported the hypothesis that the inherent asymmetry of this structure provides important spatial cues for asymmetric regulation of dynein activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7597e8e008fb751848083b521a34b8
https://pubmed.ncbi.nlm.nih.gov/16188941
https://pubmed.ncbi.nlm.nih.gov/16188941