Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Erin E. Baschal"'
Autor:
Angela M. Mitchell, Erin E. Baschal, Kristen A. McDaniel, Kimber M. Simmons, Laura Pyle, Kathleen Waugh, Andrea K. Steck, Liping Yu, Peter A. Gottlieb, Marian J. Rewers, Maki Nakayama, Aaron W. Michels
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
T cell receptor (TCR) sequences are exceptionally diverse and can now be comprehensively measured with next-generation sequencing technologies. However, a thorough investigation of longitudinal TCR repertoires throughout childhood in health and durin
Externí odkaz:
https://doaj.org/article/fdd60e79e23f4d1292274bdb7907007f
Autor:
Erin E. Baschal, Eric D. Larson, Tori C. Bootpetch Roberts, Shivani Pathak, Gretchen Frank, Elyse Handley, Jordyn Dinwiddie, Molly Moloney, Patricia J. Yoon, Samuel P. Gubbels, Melissa A. Scholes, Stephen P. Cass, Herman A. Jenkins, Daniel N. Frank, Ivana V. Yang, David A. Schwartz, Vijay R. Ramakrishnan, Regie Lyn P. Santos-Cortez
Publikováno v:
Frontiers in Genetics, Vol 10 (2020)
Previous genetic studies on susceptibility to otitis media and airway infections have focused on immune pathways acting within the local mucosal epithelium, and outside of allergic rhinitis and asthma, limited studies exist on the overlaps at the gen
Externí odkaz:
https://doaj.org/article/4e0194563fec46e391ccb7ee3b9f26b2
Autor:
KIMBER M. SIMMONS, TIMOTHY B. VIGERS, LAURA PYLE, ERIN M. YOUNGKIN, ERIN E. BASCHAL, KRISTEN MCDANIEL, LIPING YU, AARON W. MICHELS
Publikováno v:
Diabetes. 71
The incidence of type 1 diabetes continues to increase, most notably in American Hispanic (HIS) youth. Type 1 diabetes autoimmunity has not been fully characterized in HIS youth. Determining the prevalence of islet autoantibody positivity in HIS yout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f83f1d6ab182fbe3e3ce43ae05070b39
https://doi.org/10.2337/db22-1187-p
https://doi.org/10.2337/db22-1187-p
Autor:
ANGELA M. MITCHELL, ERIN E. BASCHAL, KRISTEN MCDANIEL, LAURA PYLE, KATHLEEN WAUGH, ANDREA STECK, LIPING YU, PETER GOTTLIEB, MARIAN REWERS, MAKI NAKAYAMA, AARON W. MICHELS
Publikováno v:
Diabetes. 71
In type 1 diabetes (T1D) , T cells target and destroy pancreatic beta cells. T cells express T cell receptors (TCRs) which recognize peptide antigens, and each TCR is unique to a given T cell. To understand the TCR repertoire during T1D development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc37d7676dd554cd6ddb34979404c79
https://doi.org/10.2337/db22-185-or
https://doi.org/10.2337/db22-185-or
Autor:
Melisa N. Bayrak, Xiaomi Chen, Morgan R. Bland, Matthew R.G. Taylor, Lilian Antunes, Maria V. Cattell, Ryan S. Gray, Christina A. Gurnett, Lee Niswander, Erin E. Baschal, Melissa T Cuevas, Matthew B. Dobbs, Kenneth L. Jones, Nancy H. Miller, Bruce Appel, Cambria I Wethey, Anna M. Monley, Brittan S Sutphin, George Devon Trahan, Elizabeth A Terhune
Publikováno v:
Hum Mutat
Idiopathic scoliosis (IS) is a spinal disorder affecting up to 3% of otherwise healthy children. IS has a strong familial genetic component and is believed to be genetically complex due to significant variability in phenotype and heritability. Previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3544f67d511c7162ffcc80a7fba0dd4d
https://doi.org/10.1002/humu.24162
https://doi.org/10.1002/humu.24162
Autor:
Taylor K. Armstrong, Kimber M. Simmons, Angela M. Mitchell, Aimon A. Alkanani, Erin E. Baschal, Kristen A. McDaniel, Liping Yu, Aaron W. Michels, Laura Pyle
Publikováno v:
Diabetes. 69:1763-1769
Certain HLA class II genes increase the risk for type 1 diabetes (T1D) development while others provide protection from disease development. HLA class II alleles encode MHC proteins on antigen-presenting cells, which function to present peptides and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b59ac7340c68898072616b4857f85de
https://doi.org/10.2337/db20-0038
https://doi.org/10.2337/db20-0038
Autor:
Halis Kaan, Akturk, Kasey L, Couts, Erin E, Baschal, Kagan E, Karakus, Robert J, Van Gulick, Jacqueline A, Turner, Laura, Pyle, William A, Robinson, Aaron W, Michels
Publikováno v:
JAMA Network Open. 5:e2246400
ImportanceTreatment with immune checkpoint inhibitors (ICIs) has increased survival in patients with advanced malignant melanoma but can be associated with a wide range of immune-related adverse events (irAEs). The role of human leukocyte antigen (HL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f835dca462ab3fdfeb9b6d634af5da5b
https://doi.org/10.1001/jamanetworkopen.2022.46400
https://doi.org/10.1001/jamanetworkopen.2022.46400
Autor:
Erin E. Baschal, Kathleen Waugh, Maki Nakayama, Aaron W. Michels, Aimon K. Alkanani, Marian Rewers, Angela M. Mitchell, Laurie G. Landry, Taylor K. Armstrong, Kristen McDaniel
Publikováno v:
Diabetes. 70
Type 1 diabetes (T1D) results from the T cell-mediated destruction of insulin-producing pancreatic β-cells as evidenced by CD8 and CD4 T cells being present within the inflamed islets of recent-onset T1D organ donors. We isolated, sequenced the T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee1591ee98a4b724a186be54177c8401
https://doi.org/10.2337/db21-108-or
https://doi.org/10.2337/db21-108-or
Autor:
Tori C. Bootpetch, Todd Wine, Melissa A. Scholes, Patricia J. Yoon, Michael J. Bamshad, Sven-Olrik Streubel, Daniel N. Frank, Stephen P. Cass, Harold S. Pine, Tasnee Chonmaitree, Michèle M. Sale, Herman A. Jenkins, Ayesha Yousaf, Elisabet Einarsdottir, Erin E. Baschal, Ani Manichaikul, Juha Kere, Kenny H. Chan, Petri S. Mattila, Christina L Elling, Jeremy D. Prager, Regie Lyn P. Santos-Cortez, Lena Hafrén, Norman R. Friedman, Wasyl Szeremeta, Eric D. Larson, Saima Riazuddin, Allen F. Ryan, Rehan S. Shaikh, Rafaqat Ishaq, Suzanne M. Leal, Deborah A. Nickerson, Kathleen Daly, Samuel P. Gubbels, Zubair M. Ahmed
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Otitis media (OM), a very common disease in young children, can result in hearing loss. In order to potentially replicate previously reported associations between OM and PLG, exome and Sanger sequencing, RNA-sequencing of saliva and middle ear sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29baf8c7c7adbb1c2ce8a28870aa6d39
http://hdl.handle.net/10138/320494
http://hdl.handle.net/10138/320494
Autor:
Aaron W. Michels, Liping Yu, Laura Pyle, Taylor Armstrong, Erin E. Baschal, Kristen A. McDaniel, Aimon A. Alkanani, Angela M. Mitchell, Kimber M. Simmons, Ada Admin
Certain human leucocyte antigen (HLA) class II genes increase the risk for type 1 diabetes (T1D) development while others provide protection from disease development. HLA class II alleles encode major histocompatibility complex proteins on antigen pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ca9062bc9cc8ec9fcc29a41647a6e0
https://doi.org/10.2337/figshare.12311162.v2
https://doi.org/10.2337/figshare.12311162.v2