Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Erin E Cummings"'
Autor:
Erin E Cummings, Linda P O'Reilly, Dale E King, Richard M Silverman, Mark T Miedel, Cliff J Luke, David H Perlmutter, Gary A Silverman, Stephen C Pak
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141542 (2015)
α1-antitrypsin deficiency (ATD) predisposes patients to both loss-of-function (emphysema) and gain-of-function (liver cirrhosis) phenotypes depending on the type of mutation. Although the Z mutation (ATZ) is the most prevalent cause of ATD, >120 mut
Externí odkaz:
https://doaj.org/article/d896cccbc3b349e0bf07f1e5d843ffba
Publikováno v:
Journal of Food Composition and Analysis. 71:25-27
Birch syrup is a forest product produced from tree sap using methods similar to those used in maple syrup production. This study presents the first measurements of the carbon isotope ratio of birch syrup, which is ultimately a function of tree physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1afc0d9218f497e7ed2a5d880025c26
https://doi.org/10.1016/j.jfca.2018.04.012
https://doi.org/10.1016/j.jfca.2018.04.012
Autor:
Erin E. Cummings, Stephen C. Pak, Mark T. Miedel, Linda P. O’Reilly, Cliff J. Luke, Richard M. Silverman, Gary A. Silverman, David H. Perlmutter
Publikováno v:
Genetics. 200:207-219
Familial encephalopathy with neuroserpin inclusions bodies (FENIB) is a serpinopathy that induces a rare form of presenile dementia. Neuroserpin contains a classical signal peptide and like all extracellular serine proteinase inhibitors (serpins) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7206b3817cbe9bd013e3c497edf2de68
https://doi.org/10.1534/genetics.115.176180
https://doi.org/10.1534/genetics.115.176180
Autor:
Jeong Eun Kim, William A. Banks, Yow Pin Lim, Erin E. Cummings, Walter G. Besio, Xiaodi Chen, Seon Yeong Park, Jiyong Zhang, Courtney A. Bodge, Oleksandr Makeyev, John N. Gaitanis, Barbara S. Stonestreet, Grazyna B. Sadowska
Publikováno v:
The FASEB Journal. 29:1739-1753
Impaired blood-brain barrier function represents an important component of hypoxic-ischemic brain injury in the perinatal period. Proinflammatory cytokines could contribute to ischemia-related blood-brain barrier dysfunction. IL-6 increases vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ead0a1b32f7c5f5e6a6bd5fef56331
https://doi.org/10.1096/fj.14-258822
https://doi.org/10.1096/fj.14-258822
Publikováno v:
Methods. 68:529-535
Recent breakthrough discoveries have shown that committed cell fates can be reprogrammed by genetic, chemical and environmental manipulations. The germline of the nematode Caenorhabditis elegans provides a tractable system for studying cell fate repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1afb00ff925d715f25c029e42c738cb
https://doi.org/10.1016/j.ymeth.2014.05.011
https://doi.org/10.1016/j.ymeth.2014.05.011
Autor:
Susan S. Cohen, Grazyna B. Sadowska, Xiaodi Chen, May Min, Barbara S. Stonestreet, Surendra Sharma, Erin E. Cummings
Publikováno v:
Neuroimmunomodulation. 20:264-273
Objectives: The blood-brain barrier is a selective diffusion barrier between brain parenchyma and the intravascular compartment. Tight junctions are integral components of the blood-brain barrier. Pro-inflammatory cytokines are important in the patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ea1943a7c5c37115646974bf5d45ae
https://doi.org/10.1159/000350470
https://doi.org/10.1159/000350470
Autor:
Shaun D, Darrah, Shaun H, Darrah, Jerry, Chuang, Laura M, Mohler, Xiangbai, Chen, Erin E, Cummings, Tiffany, Burnett, M Christina, Reyes-Littaua, Gary N, Galang, Amy K, Wagner
Publikováno v:
Journal of Neurotrauma. 28:43-55
The mechanisms by which Dilantin confers anticonvulsant benefits may also be neuroprotective by attenuating the acute excitatory insult in cortical and subcortical structures when the drug is given in the acute phase after traumatic brain injury (TBI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fa3ae527379609af856a50a631f650
https://doi.org/10.1089/neu.2010.1521
https://doi.org/10.1089/neu.2010.1521
Autor:
Oleksandr Makeyev, Yow Pin Lim, William A. Banks, John N. Gaitanis, Walter G. Besio, Jiyong Zhang, Grazyna B. Sadowska, Xiaodi Chen, Erin E. Cummings, Barbara S. Stonestreet, James F. Padbury
Pro-inflammatory cytokines contribute to hypoxic–ischemic brain injury. Blood–brain barrier (BBB) dysfunction represents an important component of hypoxic–ischemic brain injury in the fetus. Hypoxic–ischemic injury could accentuate systemic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6a976beb30bd3650caac080b5727f4
https://europepmc.org/articles/PMC4640327/
https://europepmc.org/articles/PMC4640327/
Autor:
Erin E. Cummings, Joshua A. Benson, David H. Perlmutter, Stephen C. Pak, Linda P. O’Reilly, Gary A. Silverman
Publikováno v:
Expert opinion on drug discovery. 9(9)
Many human diseases result from a failure of a single protein to achieve the correct folding and tertiary conformation. These so-called 'conformational diseases' involve diverse proteins and distinctive cellular pathologies. They all engage the prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097003bc98a0cf7ba16a056d9421280a
https://pubmed.ncbi.nlm.nih.gov/24998976
https://pubmed.ncbi.nlm.nih.gov/24998976
Autor:
Yow Pin Lim, Grazyna B. Sadowska, Jeong Eun Kim, Erin E. Cummings, Steven W. Threlkeld, Xiaodi Chen, Courtney A. Bodge, William A. Banks, Barbara S. Stonestreet, Walter G. Besio, John N. Gaitanis, Jiyong Zhang, Oleksandr Makeyev
Publikováno v:
Neurobiology of Disease, Vol 73, Iss, Pp 118-129 (2015)
article i nfo We have previously shown that increases in blood-brain barrier permeability represent an important compo- nent of ischemia-reperfusion related brain injury in the fetus. Pro-inflammatory cytokines could contribute to these abnormalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926b4b8c1f812c073e745361a154e3c9
https://pubmed.ncbi.nlm.nih.gov/25258170
https://pubmed.ncbi.nlm.nih.gov/25258170