Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Erin E, Mulvihill"'
Autor:
Jordan S.F. Chan, Seyed Amirhossein Tabatabaei Dakhili, Maria Areli Lorenzana-Carrillo, Keshav Gopal, Serena M. Pulente, Amanda A. Greenwell, Kunyan Yang, Christina T. Saed, Magnus J. Stenlund, Sally R. Ferrari, Indiresh A. Mangra-Bala, Tanin Shafaati, Rakesh K. Bhat, Farah Eaton, Michael Overduin, Sebastian Beck Jørgensen, Gregory R. Steinberg, Erin E. Mulvihill, Gopinath Sutendra, John R. Ussher
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114573- (2024)
Summary: Growth differentiation factor 15 (GDF15) is a peptide with utility in obesity, as it decreases appetite and promotes weight loss. Because obesity increases the risk for type 2 diabetes (T2D) and cardiovascular disease, it is imperative to un
Externí odkaz:
https://doaj.org/article/8e982b3f2425453094ab8152492fec0a
Autor:
Arianne Morissette, Erin E. Mulvihill
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 27 (2024)
Excess adiposity can contribute to metabolic complications, such as type 2 diabetes mellitus (T2DM), which poses a significant global health burden. Traditionally viewed as a chronic and irreversible condition, T2DM management has evolved and new app
Externí odkaz:
https://doaj.org/article/87d50345613e49268d6a2f732e9917ff
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4889 (2024)
Type 2 diabetes (T2D) is characterized by muscle metabolic dysfunction that exercise can minimize, but some patients do not respond to an exercise intervention. Myokine secretion is intrinsically altered in patients with T2D, but the role of myokines
Externí odkaz:
https://doaj.org/article/a17f31f344c44002b336dddd450138b7
Autor:
Evgenia Fadzeyeva, Cassandra A.A. Locatelli, Natasha A. Trzaskalski, My-Anh Nguyen, Megan E. Capozzi, Branka Vulesevic, Nadya M. Morrow, Peyman Ghorbani, Antonio A. Hanson, Ilka Lorenzen-Schmidt, Mary-Anne Doyle, Richard Seymour, Elodie M. Varin, Morgan D. Fullerton, Jonathan E. Campbell, Erin E. Mulvihill
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106748- (2023)
Summary: Mice systemically lacking dipeptidyl peptidase-4 (DPP4) have improved islet health, glucoregulation, and reduced obesity with high-fat diet (HFD) feeding compared to wild-type mice. Some, but not all, of this improvement can be linked to the
Externí odkaz:
https://doaj.org/article/213537b074c74de6ba1a3b4427a6b586
Autor:
Léa Garneau, Tasuku Terada, Matheus Mistura, Erin E. Mulvihill, Jennifer L. Reed, Céline Aguer
Publikováno v:
Physiological Reports, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract Low‐grade inflammation is central to coronary artery disease (CAD) and type 2 diabetes (T2D) and is reduced by exercise training. The objective of this study was to compare the anti‐inflammatory potential of moderate‐to‐vigorous inte
Externí odkaz:
https://doaj.org/article/fbb1a14260aa41019a69657a5a6c5bfa
Autor:
Natasha A. Trzaskalski, Branka Vulesevic, My-Anh Nguyen, Natasha Jeraj, Evgenia Fadzeyeva, Nadya M. Morrow, Cassandra A.A. Locatelli, Nicole Travis, Antonio A. Hanson, Julia R.C. Nunes, Conor O’Dwyer, Jelske N. van der Veen, Ilka Lorenzen-Schmidt, Rick Seymour, Serena M. Pulente, Andrew C. Clément, Angela M. Crawley, René L. Jacobs, Mary-Anne Doyle, Curtis L. Cooper, Kyoung-Han Kim, Morgan D. Fullerton, Erin E. Mulvihill
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty liver disease progression remains unclear. Here, we identified that DPP4 in hepatocytes but not
Externí odkaz:
https://doaj.org/article/40cdcc7f6d5742ecbe16d60323de171c
Autor:
Shaza Asif, Ri Youn Kim, Thet Fatica, Jordan Sim, Xiaoling Zhao, Yena Oh, Alix Denoncourt, Angela C. Cheung, Michael Downey, Erin E. Mulvihill, Kyoung-Han Kim
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101494- (2022)
Objective: Aberrant ketogenesis is correlated with the degree of steatosis in non-alcoholic fatty liver disease (NAFLD) patients, and an inborn error of ketogenesis (mitochondrial HMG-CoA synthase deficiency) is commonly associated with the developme
Externí odkaz:
https://doaj.org/article/541393ef70824562951e14381149227c
Autor:
Nicholas D. LeBlond, Peyman Ghorbani, Conor O'Dwyer, Nia Ambursley, Julia R.C. Nunes, Tyler K.T. Smith, Natasha A. Trzaskalski, Erin E. Mulvihill, Benoit Viollet, Marc Foretz, Morgan D. Fullerton
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1697-1706 (2020)
The dysregulation of myeloid-derived cell metabolism can drive atherosclerosis. AMP-activated protein kinase (AMPK) controls various aspects of macrophage dynamics and lipid homeostasis, which are important during atherogenesis. Using LysM-Cre to dri
Externí odkaz:
https://doaj.org/article/f36517f379a741489a56e4fcfe0c1791
Autor:
Yves Mugabo, Cheng Zhao, Ju Jing Tan, Anindya Ghosh, Scott A. Campbell, Evgenia Fadzeyeva, Frédéric Paré, Siew Siew Pan, Maria Galipeau, Julia Ast, Johannes Broichhagen, David J. Hodson, Erin E. Mulvihill, Sophie Petropoulos, Gareth E. Lim
Publikováno v:
JCI Insight, Vol 7, Iss 8 (2022)
While critical for neurotransmitter synthesis, 14-3-3 proteins are often assumed to have redundant functions due to their ubiquitous expression, but despite this assumption, various 14-3-3 isoforms have been implicated in regulating metabolism. We pr
Externí odkaz:
https://doaj.org/article/a212201235ad4383a3067ba2c4ddbc78
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Enteroendocrine cells directly integrate signals of nutrient content within the gut lumen with distant hormonal responses and nutrient disposal via the production and secretion of peptides, including glucose-dependent insulinotropic polypeptide (GIP)
Externí odkaz:
https://doaj.org/article/c1e861226b464be39ed7810bb2e08f43