Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Erin E, McClelland"'
Autor:
Margaret E. Bauer, Samina Akbar, Timothy J. Bauler, Jessica Chacon, Erin E. McClelland, Shawn Staudaher, Yuan Zhao
Publikováno v:
Medical Education Online, Vol 29, Iss 1 (2024)
Purpose Medical school educators face challenges determining which new and emerging topics to incorporate into medical school curricula, and how to do so. A study was conducted to gain a better understanding of the integration of emerging topics rela
Externí odkaz:
https://doaj.org/article/cce3b745560b4b62bab1e2fe1a35fa5a
Autor:
Hari H. Rao, Erin E. McClelland
Publikováno v:
Journal of Fungi, Vol 10, Iss 9, p 607 (2024)
Fungal infections often disproportionately affect males over females. Since the NIH mandated in 2016 that researchers test their hypotheses in both biological sexes, numerous other fungal infections/colonizations have been found to exhibit sex-specif
Externí odkaz:
https://doaj.org/article/b43febc6656e4bbdbc6ef6b8bab579ef
Autor:
Emily S. Smith-Peavler, Ronakkumar Patel, Adejumoke Mary Onumajuru, Bethany G. Bowring, Joyce L. Miller, Jean Michel Brunel, Julianne T. Djordjevic, Moses M. Prabu, Erin E. McClelland
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1239 (2022)
Cryptococcus neoformans (Cn) is a pathogenic yeast that is the leading cause of fungal meningitis in immunocompromised patients. Various Cn virulence factors, such as the enzyme laccase and its product melanin, phospholipase, and capsular polysacchar
Externí odkaz:
https://doaj.org/article/c19638ae11774cb8ad855ebd49f17efc
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract Background Cryptococcus neoformans, the causative agent of cryptococcosis, causes ~ 181,000 deaths annually, with males having a higher incidence of disease than females (7M:3F). The reason for this sex bias remains unclear. We hypothesized
Externí odkaz:
https://doaj.org/article/e3ccd65fdfab49ffa9311b3aa473613d
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Cryptococcus neoformans, a spore-producing pathogenic yeast, affects immunocompromised individuals causing meningoencephalitis. Once C. neoformans is introduced via the respiratory tract, it is engulfed by macrophages and other phagocytes. One of C.
Externí odkaz:
https://doaj.org/article/3e4f9930650c42708059575187c07d46
Autor:
Aarthi Subramani, Prianca Griggs, Niah Frantzen, James Mendez, Jamila Tucker, Jada Murriel, Linda M Sircy, Grace E Millican, Erin E McClelland, Rebecca L Seipelt-Thiemann, David E Nelson
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0233818 (2020)
Macrophages serve as a first line of defense against infection with the facultative intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate phagocytic cells to destroy ingested Cn is strongly influenced by polarizat
Externí odkaz:
https://doaj.org/article/ae07982466ca4e43b3029e782d2c1994
Autor:
Muhammad Fariz Ali, Stephen M. Tansie, John R. Shahan, Rebecca L. Seipelt-Thiemann, Erin E. McClelland
Publikováno v:
Pathogens, Vol 9, Iss 9, p 732 (2020)
To gain insight into how pathogens adapt to new hosts, Cryptococcus neoformans (H99W) was serially passaged in Galleria mellonella. The phenotypic characteristics of the passaged strain (P15) and H99W were evaluated. P15 grew faster in hemolymph than
Externí odkaz:
https://doaj.org/article/5286c87423e34e43a2a5dc04c2b879fd
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pathogenic cryptococci are encapsulated yeast that can cause severe meningoencephalitis. Existing therapeutic options are dated and there is a growing need for new alternative antifungal agents for these fungi. Here we report novel inhibition of path
Externí odkaz:
https://doaj.org/article/ee4d5f5e03e248e2ba06db28c7947dd9
Autor:
Aarthi Subramani, Maria E. L. Hite, Hursha Kondee, Grace E. Millican, Erin E. McClelland, Rebecca L. Seipelt-Thiemann, David E. Nelson
Macrophages are highly dynamic innate immune cells that adopt temporary phenotypes, known as polarization states, in response to changing environmental signals to combat microbial infection and contribute to the maintenance of tissue homeostasis. Dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b00e6ed0069617b7750a64b5e5ac367
https://doi.org/10.1101/2022.08.16.504142
https://doi.org/10.1101/2022.08.16.504142
Autor:
Erin E McClelland, Udupi A Ramagopal, Johanna Rivera, James Cox, Antonio Nakouzi, Moses M Prabu, Steven C Almo, Arturo Casadevall
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005849 (2016)
The pathogenic yeast Cryptococcus neoformans causes cryptococcosis, a life-threatening fungal disease. C. neoformans has multiple virulence mechanisms that are non-host specific, induce damage and interfere with immune clearance. Microarray analysis
Externí odkaz:
https://doaj.org/article/a4dfcd385c3c48659ed7ea08548cff0d