Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Erin E, Kershaw"'
Autor:
Shawn R. Eagle, Mahesh K. Basantani, Jonathan Preszler, Natalie Sherry, Peyton McIntyre, Erin E. Kershaw, Ava M. Puccio, David O. Okonkwo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome has been associated with worse outcomes from severe traumatic brain injury (TBI). The NLRP3 inflammasome is also strongly associated with other pro-inflammatory con
Externí odkaz:
https://doaj.org/article/7fb4debc4a024297924d96c6fd123faa
Autor:
Sicheng Zhang, Kevin J. Williams, Amandine Verlande-Ferrero, Alvin P. Chan, Gino B. Su, Erin E. Kershaw, James E. Cox, John Alan Maschek, Suzanne N. Shapira, Heather R. Christofk, Thomas Q. de Aguiar Vallim, Selma Masri, Claudio J. Villanueva
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 2, Pp 100434- (2024)
Adipose tissue is the site of long-term energy storage. During the fasting state, exercise, and cold exposure, the white adipose tissue mobilizes energy for peripheral tissues through lipolysis. The mobilization of lipids from white adipose tissue to
Externí odkaz:
https://doaj.org/article/ff3c3ea9925a42a1b4513e62d017e176
Autor:
Anna C. Rivara, Emily M. Russell, Jenna C. Carlson, Alysa Pomer, Take Naseri, Muagututia Seifuiva Reupena, Samantha L. Manna, Satupaitea Viali, Ryan L. Minster, Daniel E. Weeks, James P. DeLany, Erin E. Kershaw, Stephen T. McGarvey, Nicola L. Hawley
Publikováno v:
PLoS ONE, Vol 19, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/43ee9cdf6ae24bacaa47c657b958e306
Autor:
Mingqi Zhou, Ian Tamburini, Cassandra Van, Jeffrey Molendijk, Christy M Nguyen, Ivan Yao-Yi Chang, Casey Johnson, Leandro M Velez, Youngseo Cheon, Reichelle Yeo, Hosung Bae, Johnny Le, Natalie Larson, Ron Pulido, Carlos HV Nascimento-Filho, Cholsoon Jang, Ivan Marazzi, Jamie Justice, Nicholas Pannunzio, Andrea L Hevener, Lauren Sparks, Erin E Kershaw, Dequina Nicholas, Benjamin L Parker, Selma Masri, Marcus M Seldin
Publikováno v:
eLife, Vol 12 (2024)
Inter-organ communication is a vital process to maintain physiologic homeostasis, and its dysregulation contributes to many human diseases. Given that circulating bioactive factors are stable in serum, occur naturally, and are easily assayed from blo
Externí odkaz:
https://doaj.org/article/b0b0c3945a2343e1a77c073ec88b5282
Autor:
Jenna C. Carlson, Mohanraj Krishnan, Samantha L. Rosenthal, Emily M. Russell, Jerry Z. Zhang, Nicola L. Hawley, Jaye Moors, Hong Cheng, Nicola Dalbeth, Janak R. de Zoysa, Huti Watson, Muhammad Qasim, Rinki Murphy, Take Naseri, Muagututi’a Sefuiva Reupena, Satupa‘itea Viali, Lisa K. Stamp, John Tuitele, Erin E. Kershaw, Ranjan Deka, Stephen T. McGarvey, Tony R. Merriman, Daniel E. Weeks, Ryan L. Minster
Publikováno v:
HGG Advances, Vol 4, Iss 1, Pp 100155- (2023)
Summary: Current understanding of lipid genetics has come mainly from studies in European-ancestry populations; limited effort has focused on Polynesian populations, whose unique population history and high prevalence of dyslipidemia may provide insi
Externí odkaz:
https://doaj.org/article/733af63f641347d89dd47716fcd3a8aa
Autor:
Gundala Venkata Naveen Kumar, Keito Hoshitsuki, Sanjay Rathod, Manda J. Ramsey, Lauren Kokai, Erin E. Kershaw, Wen Xie, Christian A. Fernandez
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3779-3790 (2021)
PEGylated-l-asparaginase (PEG-ASNase) is a chemotherapeutic agent used to treat pediatric acute lymphoblastic leukemia (ALL). Its use is avoided in adults due to its high risk of liver injury including hepatic steatosis, with obesity and older age co
Externí odkaz:
https://doaj.org/article/030f734db6814ff9a311d060430fa2e6
Autor:
Sakurako Oyama, Rachel L. Duckham, Kendall J. Arslanian, Erin E. Kershaw, Joshua A. Strayer, Ulai T. Fidow, Take Naseri, Nicola L. Hawley
Publikováno v:
Annals of Human Biology, Vol 48, Iss 4, Pp 346-349 (2021)
Background The “Foafoaga O le Ola (Beginning of Life)” study is a prospective birth cohort of n = 160 Samoan mother-infant dyads established in 2017–2018. A primary study aim is to explore how a missense variant at CREBRF rs373863828 impacts gr
Externí odkaz:
https://doaj.org/article/6046cbf9dadc4e3996a53642bfde6113
Autor:
Laura Pajed, Ulrike Taschler, Anna Tilp, Peter Hofer, Petra Kotzbeck, Stephanie Kolleritsch, Franz P. W. Radner, Isabella Pototschnig, Carina Wagner, Margarita Schratter, Sandra Eder, Sabrina Huetter, Renate Schreiber, Guenter Haemmerle, Thomas O. Eichmann, Martina Schweiger, Gerald Hoefler, Erin E. Kershaw, Achim Lass, Gabriele Schoiswohl
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Pajed et al. investigate the role of adipocyte hormone-sensitive lipase (HSL) in whole body energy homeostasis. They show that adipocyte-specific HSL Knockout (AHKO) mice fed high fat diet develop fatty liver. Interestingly, this phenotype reverses i
Externí odkaz:
https://doaj.org/article/489219dde80844a090448c922d5f0fbd
Publikováno v:
Hepatology Communications, Vol 3, Iss 10, Pp 1347-1355 (2019)
Weight loss is the primary intervention for nonalcoholic fatty liver disease (NAFLD). A decrease in resting metabolic rate (RMR) out of proportion to the degree of weight loss may promote weight regain. We aimed to determine the impact of hepatic ste
Externí odkaz:
https://doaj.org/article/244a70a7fff74864ab926f6cbc969755
Autor:
Robert S. Rosenson, Daniel Gaudet, Christie M. Ballantyne, Seth J. Baum, Jean Bergeron, Erin E. Kershaw, Patrick M. Moriarty, Paolo Rubba, David C. Whitcomb, Poulabi Banerjee, Andrew Gewitz, Claudia Gonzaga-Jauregui, Jennifer McGinniss, Manish P. Ponda, Robert Pordy, Jian Zhao, Daniel J. Rader
Publikováno v:
Nature Medicine. 29:729-737
Severe hypertriglyceridemia (sHTG) is an established risk factor for acute pancreatitis. Current therapeutic approaches for sHTG are often insufficient to reduce triglycerides and prevent acute pancreatitis. This phase 2 trial (NCT03452228) evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f5cffe8051f443eca39b064bb26f9c
https://doi.org/10.1038/s41591-023-02222-w
https://doi.org/10.1038/s41591-023-02222-w