Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Erin C. Macaulay"'
Autor:
Chiemi F. Lynch-Sutherland, Aniruddha Chatterjee, Peter A. Stockwell, Michael R. Eccles, Erin C. Macaulay
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Transposable elements (TEs) have an established role as important regulators of early human development, functioning as tissue-specific genes and regulatory elements. Functional TEs are highly active during early development, and interact with import
Externí odkaz:
https://doaj.org/article/0525938dec4c4650af20c8798fb738e2
Autor:
Teena K. J. B. Gamage, William Schierding, Daniel Hurley, Peter Tsai, Jackie L. Ludgate, Chandrakanth Bhoothpur, Lawrence W. Chamley, Robert J. Weeks, Erin C. Macaulay, Joanna L. James
Publikováno v:
Epigenetics, Vol 13, Iss 12, Pp 1154-1173 (2018)
The placenta is a vital fetal exchange organ connecting mother and baby. Specialised placental epithelial cells, called trophoblasts, are essential for adequate placental function. Trophoblasts transform the maternal vasculature to allow efficient bl
Externí odkaz:
https://doaj.org/article/128c01ec68fe4a9784aedbd76ec11c86
Autor:
Sultana Mehbuba Hossain, Chiemi F. Lynch-Sutherland, Aniruddha Chatterjee, Erin C. Macaulay, Michael R. Eccles
Publikováno v:
Epigenomes, Vol 5, Iss 3, p 16 (2021)
Cancer is the second leading cause of mortality and morbidity in the developed world. Cancer progression involves genetic and epigenetic alterations, accompanied by aggressive changes, such as increased immune evasion, onset of metastasis, and drug r
Externí odkaz:
https://doaj.org/article/f781949829324c42894dcefa63cdfee6
Autor:
Aniruddha Chatterjee, Erin C. Macaulay, Euan J. Rodger, Peter A. Stockwell, Matthew F. Parry, Hester E. Roberts, Tania L. Slatter, Noelyn A. Hung, Celia J. Devenish, Ian M. Morison
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 7, Pp 1911-1921 (2016)
The human placenta is hypomethylated compared to somatic tissues. However, the degree and specificity of placental hypomethylation across the genome is unclear. We assessed genome-wide methylation of the human placenta and compared it to that of the
Externí odkaz:
https://doaj.org/article/a2e451ef12624c9899029645437ad823
Autor:
Ashley L. Reily-Bell, Amanda Fisher, Bryony Harrison, Sara Bowie, Sankalita Ray, Mary Hawkes, Lyn M. Wise, Ryuji Fukuzawa, Erin C. Macaulay, Celia J. Devenish, Noelyn A. Hung, Tania L. Slatter
Publikováno v:
Pathogens, Vol 9, Iss 3, p 239 (2020)
Whether HPV is causative of pregnancy complications is uncertain. E6 and E7 affect functions underling preeclampsia (PET) in cultured trophoblasts, but whether E6 and E7 is produced in the placenta is uncertain. Here, we investigated whether E6/E7 wa
Externí odkaz:
https://doaj.org/article/993a9947cb01450091a74c79cb6ba4e8
Autor:
Teena K. J. B. Gamage, William Schierding, Peter Tsai, Jackie L. Ludgate, Lawrence W. Chamley, Robert J. Weeks, Erin C. Macaulay, Joanna L. James
Publikováno v:
Biology Open, Vol 7, Iss 8 (2018)
The placenta is a fetal exchange organ connecting mother and baby that facilitates fetal growth in utero. DNA methylation is thought to impact placental development and function. Global DNA methylation studies using human placental lysates suggest th
Externí odkaz:
https://doaj.org/article/41831f45c781426aa9310e1ddef19c12
Autor:
Hidekazu Homma, Tania L. Slatter, Ryuji Fukuzawa, Celia Devenish, Izumi Honda, Robert C. Day, Noelyn Hung, Aniruddha Chatterjee, Erin C. Macaulay, Abdulmonem A. Alsaleh, Robert J. Weeks, Suzan N. Almomani, Ian M. Morison
Publikováno v:
Placenta. 110:16-23
Introduction Pre-eclampsia (PE) is a dangerous placental condition that can lead to premature labour, seizures and death of mother and infant. Several studies have identified altered placental DNA methylation in PE; however, there is widespread incon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6766532cebcef617a63c58eaa13712a
https://doi.org/10.1016/j.placenta.2021.05.005
https://doi.org/10.1016/j.placenta.2021.05.005
Autor:
Ryan M, Powell, Sharon, Pattison, Jiri C, Moravec, Basharat, Bhat, Nada, Guirguis, David, Markie, Greg T, Jones, Jason, Copedo, Cristin G, Print, Ian M, Morison, Alex, Gavryushkin, Bronwyn, Gray, Lisa J, Wyeth, Mike R, Eccles, Erin C, Macaulay
Publikováno v:
Cold Spring Harbor molecular case studies. 8(3)
Tuberous sclerosis complex (TSC) is an inheritable disorder characterized by the formation of benign yet disorganized tumors in multiple organ systems. Germline mutations in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5f4b3d8b7f1b05f16417c634fa2a9e2
https://pubmed.ncbi.nlm.nih.gov/35483879
https://pubmed.ncbi.nlm.nih.gov/35483879
Autor:
Michael R. Eccles, Peter A. Stockwell, Aniruddha Chatterjee, Erin C. Macaulay, Chiemi F Lynch-Sutherland
Publikováno v:
Current protocolsLiterature Cited. 1(8)
Transposable elements (TEs) are key regulators of both development and disease; however, their repetitive nature presents substantial computational challenges to their analysis. Due to a lack of computational tools and suitable analysis frameworks, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523362c7d6ee6e875f84745299170be4
https://pubmed.ncbi.nlm.nih.gov/34387946
https://pubmed.ncbi.nlm.nih.gov/34387946