Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Erin C Klein"'
Autor:
Upendra A. Argikar, William S. Oetting, Erin C. Klein, Rory P. Remmel, James C. Cloyd, Smita Kshirsagar, Jeannine M. Conway, Angela K. Birnbaum, Ilo E. Leppik
Publikováno v:
Epilepsy Research. 71:54-63
Phenytoin (PHT) is primarily metabolized to 5-(4′-hydroxyphenyl)-5-phenylhydantoin ( p -HPPH), accounting for 67–88% of an administered dose in humans. p - HPPH is formed by the cytochrome (CYP) 450 enzymes CYP2C9 and CYP2C19, then glucuronidated
Autor:
Marc K. Halushka, Tammy M. Holm, Francesco Ramirez, Daniel B. Rifkin, Kathleen L. Gabrielson, Ronald D. Cohn, Megan Podowski, Bart Loeys, Djahida Bedja, G. Liu, Jennifer P Habashi, Loretha Myers, David L. Huso, Daniel P. Judge, Enid Neptune, Erin C Klein, Harry C. Dietz, Timothy K. Cooper, Luca Carta, Carla L. Calvi
Publikováno v:
Journal of the American Society of Nephrology. 17:1759-1764
Marfan syndrome is a disease resulting from a mutation of the gene coding for fibrillin-1 ([1][1]), a protein that forms fibrils in the extracellular matrix, thus depleting elastic tissue of a key building block. As a result, the ascending aorta of t
Autor:
Harry C. Dietz, Megan Podowski, Marc K. Halushka, Kathleen L. Gabrielson, Tammy M. Holm, Erin C Klein, Djahida Bedja, David L. Huso, Loretha Myers, Timothy K. Cooper, Luca Carta, Francesco Ramirez, Carla L. Calvi, Ronald D. Cohn, Bart Loeys, Daniel B. Rifkin, Enid Neptune, Daniel P. Judge, Jennifer P Habashi, Guosheng Liu
Publikováno v:
Science. 312:117-121
Aortic aneurysm and dissection are manifestations of Marfan syndrome (MFS), a disorder caused by mutations in the gene that encodes fibrillin-1. Selected manifestations of MFS reflect excessive signaling by the transforming growth factor–β (TGF-β
Autor:
Arshia Soleimani, Christel Van Erp, Tammy M. Holm, Colette M. Ap Rhys, Christopher W. Ward, Jennifer P Habashi, Francesco Ramirez, Matthew Gamradt, Bart Loeys, Daniel P. Judge, Matthew T Lisi, Harry C. Dietz, Erin C Klein, Ronald D. Cohn
Skeletal muscle has the ability to achieve rapid repair in response to injury or disease. Many individuals with Marfan syndrome (MFS), caused by a deficiency of extracellular fibrillin-1, exhibit myopathy and often are unable to increase muscle mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c493aa70fcd8d89666cc17b0cfeef1b8
https://europepmc.org/articles/PMC3138130/
https://europepmc.org/articles/PMC3138130/
Autor:
Christopher W. Ward, Tammy M. Holm, Ronald D. Cohn, Jennifer P Habashi, Harry C. Dietz, Colette M. Ap Rhys, Erin C Klein, Daniel P. Judge, Bart Loeys, Arshia Soleimani, Matthew Gamradt, Francesco Ramirez, Matthew T Lisi, Christel Van Erp
Publikováno v:
Nature Medicine. 13:511-511
Nat. Med. 12, 204–210 (2007); published online 21 January 2007; corrected after print 27 February 2007 In the version of this article initially published, the same panels were inadvertently used to show negative pSmad2/3 and periostin staining in m