Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Erin Burch"'
Autor:
Brent Delzer, Dawei Liang, David Szwerdszarf, Isadora Rodriguez, Gonzalo Mardones, Sivamani Elumalai, Francine Johnson, Samson Nalapalli, Rachel Egger, Erin Burch, Kerry Meier, Juan Wei, Xiujuan Zhang, Huaping Gui, Huaibing Jin, Huan Guo, Kun Yu, Yubo Liu, Becky Breitinger, Ana Poets, Jason Nichols, Wan Shi, David Skibbe, Qiudeng Que, Timothy Kelliher
Publikováno v:
Crop Journal, Vol 12, Iss 1, Pp 314-319 (2024)
The introduction of alleles into commercial crop breeding pipelines is both time consuming and costly. Two technologies that are disrupting traditional breeding processes are doubled haploid (DH) breeding and genome editing (GE). Recently, these tech
Externí odkaz:
https://doaj.org/article/a523bad92c914301881cc5e6becf3992
Autor:
Yuejin Sun, Zhongying Chen, Timothy Kelliher, Xiujuan Su, Peter E. Wittich, James H. Roberts, Jamie McCuiston, Dakota Starr, Qiudeng Que, Nic J Bate, Julie Green, Guozhu Tang, Weining Gu, Shujie Dong, Tim Strebe, Jared Carter, Erin Burch
Publikováno v:
Nature Biotechnology. 37:287-292
Genome editing using CRISPR-Cas9 works efficiently in plant cells1, but delivery of genome-editing machinery into the vast majority of crop varieties is not possible using established methods2. We co-opted the aberrant reproductive process of haploid
Autor:
Scott E. Strome, Henrik S. Olsen, Haoping Sun, Xiaoyu Zhang, John C. Papadimitriou, Erin Burch, David S. Block, Edward So, Søren M. Bentzen, Susan Kinsey, Emmanuel Y. Mérigeon, Cinthia B. Drachenberg
Publikováno v:
Journal of Autoimmunity. 84:97-108
There is a lack of effective targeted therapies for the treatment of complement dependent diseases. We developed two recombinant Fc multimers, G207 and G211, with limited ability to interact with low/moderate affinity FcγRs, but with high avidity fo
Autor:
Henrik S. Olsen, Shaodong Chen, Erin Burch, Edward So, David S. Block, Emmanuel Y. Mérigeon, Scott E. Strome, Xiaoyu Zhang, Hua Zhou
Publikováno v:
The Journal of Immunology. 196:1165-1176
We developed a fully recombinant anti-CD20 protein derived from cDNA encoding one Fab domain, two IgG1 Fc regions, the IgG2 hinge, and an isoleucine zipper. This protein, called GB4542, contained both the homodimer and higher-order multimers. Binding
Autor:
Edward So, Yaping Ji, Julian D Amin, Xiaoyu Zhang, Ariana Khaladj-Ghom, Ronna Hertzano, Erin Burch, Yang Song, Hua Zhou, Scott E. Strome, Haoping Sun, Søren M. Bentzen, Shaodong Chen
Publikováno v:
Immunobiology. 224(3)
Given the heightened interest in manipulation of co-signaling cascades for cancer immunotherapy, we sought to determine how/whether tumors decorated with therapeutic monoclonal antibodies (mAbs) impact the expression of co-signaling molecules on huma
Autor:
Xiaoyu Zhang, Gregory Weber, David S. Block, Edward So, Erin Burch, Henrik S. Olsen, Xianfeng Li, Gregory LaRosa, Scott E. Strome, Haiping Hao, Mark C. McCroskey, Donald Bennett, Hua Zhou, Jane Owens, Emmanuel Y. Mérigeon, Denis Rybin
Publikováno v:
JCI insight. 4(2)
The antiinflammatory effects of i.v. Ig (IVIG) in the treatment of autoimmune disease are due, in part, to the Fc fragments of Ig aggregates. In order to capitalize on the known antiinflammatory and tolerogenic properties of Ig Fc aggregates, we crea
Autor:
Timothy, Kelliher, Dakota, Starr, Xiujuan, Su, Guozhu, Tang, Zhongying, Chen, Jared, Carter, Peter E, Wittich, Shujie, Dong, Julie, Green, Erin, Burch, Jamie, McCuiston, Weining, Gu, Yuejin, Sun, Tim, Strebe, James, Roberts, Nic J, Bate, Qiudeng, Que
Publikováno v:
Nature biotechnology. 37(3)
Genome editing using CRISPR-Cas9 works efficiently in plant cells
Autor:
Lori Ferrins, Melissa J. Buskes, Madison M. Kapteyn, Hannah N. Engels, Suzanne E. Enos, Chenyang Lu, Dana M. Klug, Baljinder Singh, Antonio Quotadamo, Kelly Bachovchin, Westley F. Tear, Andrew E. Spaulding, Katherine C. Forbes, Seema Bag, Mitch Rivers, Catherine LeBlanc, Erin Burchfield, Jeremy R. Armand, Rosario Diaz-Gonzalez, Gloria Ceballos-Perez, Raquel García-Hernández, Guiomar Pérez-Moreno, Cristina Bosch-Navarrete, Claudia Gómez-Liñán, Luis Miguel Ruiz-Pérez, Francisco Gamarro, Dolores González-Pacanowska, Miguel Navarro, Kojo Mensa-Wilmot, Michael P. Pollastri, Dennis E. Kyle, Christopher A. Rice
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0f2b847142f74e518b6ce0db61ac7a90
Autor:
Michelle A. Sallin, Ling Cai, Edward So, Xiaoyu Zhang, Erin Burch, Wei Lin, Andrei I. Chapoval, Scott E. Strome
Publikováno v:
Cancer Immunology, Immunotherapy. 63:947-958
Agonistic monoclonal antibodies (mAbs) directed against the co-signaling molecule CD137 (4-1BB) elicit potent anti-tumor immunity in mice. This anti-tumor immunity has traditionally been thought to result from the ability of the Fab portion of anti-C
Autor:
William S. Twadell, Ling Cai, Edward So, Scott E. Strome, Xiaoyu Zhang, Dan H. Schulze, David S. Block, Bhawna Poonia, Erin Burch, Ajay N. Jain, Emmanuel Y. Mérigeon, Henrik S. Olsen, Nader Hanna, Harris G. Yfantis, Ravi Vyzasatya, Siaw L. Chan
Publikováno v:
European Journal of Cancer. 49:3344-3352
Tumour antigen targeted antibodies (mAbs) can induce natural killer (NK) cells to kill tumours through antibody dependent cellular cytotoxicity (ADCC) upon engagement of NK cell expressed FcγRIIIa. FcγRIIIa polymorphisms partially dictate the poten