Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial

Autor: James M Chamberlain, Jaideep Kapur, Shlomo Shinnar, Jordan Elm, Maija Holsti, Lynn Babcock, Alex Rogers, William Barsan, James Cloyd, Daniel Lowenstein, Thomas P Bleck, Robin Conwit, Caitlyn Meinzer, Hannah Cock, Nathan B Fountain, Ellen Underwood, Jason T Connor, Robert Silbergleit, Emily Gray, Sonya Gunter, Amy Fansler, Valerie Stevenson, Erin Bengelink, Deneil Harney, Mickie Speers, Joy Black, Natalie Fisher, Donna Harsh, Arthi Ramakrishnan, Lindsey Harris, Nia Bozeman, Aimee Spiteri, Yuko Palesch, Holly Tillman, Wenle Zhao, Qi Pauls, Chris Arnaud, Catherine R. Dillon, Jodie Riley, Teldon Alford, Cassidy Conner, Lisa Coles, Abhi Sathe, Scott Janis, Adam Hartman, Brandy Fureman, Eugen Trinka, David Treiman, David Wright, Jonathan Ratcliff, Alex Hall, Alaina Williams, Harold Simon, Nicholas Stanley, Roger Humphries, Theresa Mims, Joann Short, Elizabeth Jones, Misty Ottman, Nina Gentile, Derek Isenberg, Hannah Reimer, Vernon Sayoc Kalugdan, Claude Hemphill, Debbie Yi Madhok, Jeany Duncan, Dominica Randazzo, James Quinn, Anita Visweswaran, Rosen Mann, Opeolu Adeoye, Jason McMullan, Brandon Foreman, Sara Keegan, Michelle Biros, Brian Driver, Audrey Hendrickson, Jamie Stang, Christopher Lewandowski, Joseph Miller, Kaleem Chaudhry, Shannen Berry, Craig Warden, Rachel Blake, Jennifer NB Cook, Erin Sabolick, Antoine Selman, Katrina Kissman, Monica Moore, J. Stephen Huff, Lea Becker, Jan Claassen, Angela Velazquez, Cristina Falo, Zlatan Coralic, Jackie Grupp-Phelan, Jill Baren, Angela Ellison, Ashley Woodford, Ima Samba, Marlena Kittick, Ralph Riviello, John Massey, Lisa Bonacquisti, Steven Levine, Sergey Motov, Christian Fromm, Rukhsana Hossain, Antonios Likourezos, Illya Pushkar, Thomas Terndrup, Salman Khaliqdina, Michael Hill, Bjorn Peterson, Alexia Terwilliger, Joseph Holm, Kyra Wicklund, Sandi Wewerka, Robert Welch, Claire Pearson, Vijaya Arun Kumar, Farhan Ayaz, Saikat Bhuiyan, Valerie H. Mika, Lola Morgan, Floyd Jones, Lorraine Dishman, Thomas Henry, Ford Erickson, Abbey Staugaitis, Chloe Lawyer, Kathleen Miller, Clif Callaway, Alexandra Urban, Sara DiFiore, Peter Adams, Brian Baum, Jason Nomura, Barbara Davis, Tom Aufderheide, Amanda Emmrich, Melissa Mena, Jacob Labinski, Chinwe Ogedegbe, Diana McCarthy, Arelis Villot-Santiago, Joshua Goldstein, Eric S. Rosenthal, Abigail Cohen, Chen Mei Su, Greg Tirrell, Melissa Howell, Marissa Hendrickson, Dan Nerheim, Eric Jaton, Barbara Biney, Christopher Gibson, Erica Dahlmeier, Katherine (Lamond) Blackburn, Oluwarotimi (Tim) Vaughan-Ogunlusi, Shahriar Zehtabchi, Richard Sinert, Bryce Petty, Scott Youngquist, Margaret Carlson, Nadege Gilles, Sarah (Zelonis) Weingast, Barney Stern, Jennifer Hopp, Virginia Ganley, Joseph Ornato, Christopher Hogan, Alan Payne, Kate Shreve, Peter Dayan, Nathan Kuppermann, Kurt Denninghoff, Rachel Stanley, Richard Ruddy, E. Brooke Lerner, J. Michael Dean, Charles Casper, Lise Nigrovic, Walt Schalick, Doug Nelson, Bobbe Thomas, Pamela Okada, Amanda Lee, Natasha Truesdale, Steven Chan, Mhadhumithaa Naresh, Venita Robinson, Jieun Hwang, Kristi Carlston, Michael Dela Cruz, Toni Harbour, Reena Karki, Daniel M. Cohen, Amy Nowakowski, Cindy Lin, Erin Fisher Kenny, Dale Steele, Lisa H. Merck, Erin Ryan, Kristin Basso, Lesley (Wasilewski) D'Urso, Kathleen Brown, Gina Nauman, Matthew Ledda, Sean Gillen, Vanessa Grant, Cheryl Vance, Daniel K. Nishijima, Kyle Pimenta, Noelle Herzog, Jonathan Bennett, Christine Eisenhart, Danny Thomas, Duke Wagner, Robert W. Hickey, Rose Azrak, Daniel Rubalcava, Juan Mondragon, Victor Gonzalez, Maha Khalil, Kristina Hart, Sara Parker, Angela Lumba-Brown, Kim Quayle, Sri Chinta, Debra Robinson, Maria Kwok, Brooke Peery, Julie Ochs, Leonor Suarez

Publikováno v: Lancet

Summary Background Benzodiazepine-refractory, or established, status epilepticus is thought to be of similar pathophysiology in children and adults, but differences in underlying aetiology and pharmacodynamics might differentially affect response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6869e0423e7ad726ac8ad833426f4803
https://europepmc.org/articles/PMC7241415/

Intensive Blood Pressure Reduction and Spot Sign in Intracerebral Hemorrhage : A Secondary Analysis of a Randomized Clinical Trial.

Autor: Morotti, Andrea, Brouwers, Bart, Romero, Javier M., Jessel, Michael J., Vashkevich, Anastasia, Schwab, Kristin, Afzal, Mohammad Rauf, Cassarly, Christy, Greenberg, Steven M., Martin, Renee Hebert, Qureshi, Adnan I., Rosand, Jonathan, Goldstein, Joshua N.

Publikováno v: JAMA Neurology; Aug2017, Vol. 74 Issue 8, p950-960, 11p