Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Erin Aguero"'
Autor:
Sudarshan R Iyer, Kevin Nusser, Kristen Jones, Pushkar Shinde, Clare Keddy, Catherine Z Beach, Erin Aguero, Jeremy Force, Ujwal Shinde, Monika A Davare
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract ROS1 is the largest receptor tyrosine kinase in the human genome. Rearrangements of the ROS1 gene result in oncogenic ROS1 kinase fusion proteins that are currently the only validated biomarkers for targeted therapy with ROS1 TKIs in patient
Externí odkaz:
https://doaj.org/article/808793d75f2f413c9604e051833dd047
Autor:
Sudarshan R. Iyer, Kevin Nusser, Kristen Jones, Pushkar Shinde, Catherine Z. Beach, Clare Keddy, Erin Aguero, Jeremy Force, Ujwal Shinde, Monika A. Davare
Chromosomal rearrangements ofROS1generate ROS1 tyrosine kinase fusion proteins that are established oncogenes predicting effectiveness of tyrosine kinase inhibitors (TKI) treatment. The cancer genome reveals nonsynonymous missense mutations inROS1,ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11e802b0922310d450acde7aec8df68a
https://doi.org/10.1101/2022.12.27.521482
https://doi.org/10.1101/2022.12.27.521482
Autor:
Sudarshan R. Iyer, Kevin Nusser, Kristen Jones, Pushkar Shinde, Catherine Z. Beach, Clare Keddy, Erin Aguero, Jeremy Force, Ujwal Shinde, Monika A. Davare
Publikováno v:
Cancer Research. 83:3926-3926
ROS1 encodes the largest receptor tyrosine kinase (RTK) in the human genome. Chromosomal rearrangements of the ROS1 gene generate oncogenic ROS1 fusion proteins that have been successfully targeted with tyrosine kinase inhibitors (TKIs), most notably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8662e85930b4578ae61571025e7f284a
https://doi.org/10.1158/1538-7445.am2023-3926
https://doi.org/10.1158/1538-7445.am2023-3926