DNA Methylation of PGC-1α Is Associated With Elevated mtDNA Copy Number and Altered Urinary Metabolites in Autism Spectrum Disorder

Autor: Sophia Bam, Erin Buchanan, Caitlyn Mahony, Colleen O’Ryan

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Autism spectrum disorder (ASD) is a complex disorder that is underpinned by numerous dysregulated biological pathways, including pathways that affect mitochondrial function. Epigenetic mechanisms contribute to this dysregulation and DNA methylation i

Externí odkaz: https://doaj.org/article/9b8ff11c7dbf4400a076f8549b26f12c

Transmission Electron Microscopy Reveals Propionic Acid-induced Alterations to Mitochondrial Morphology in SH-SY5Y Cells

Autor: Erin Buchanan, Caitlyn Mahony, Sophia Bam, Mohamed Jaffer, Sarah Macleod, Mignon Van Der Watt, Caron Jacobs, Colleen O'Ryan

Mitochondrial dysregulation is implicated in numerous neurological disorders. Mitochondrial dynamics, including biogenesis, fusion and fission, are essential components of mitostasis which is modulated by complex regulatory mechanisms. Although expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f55601231908d0f20409268198348c

Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample

Autor: Bence, Bago, John, Protzko, Tamas, Nagy, Rink, Hoekstra, Bence, Palfi, Alain, Quiamzade, Mattiassi, Alan, Alasdair, Gordon-Finlayson, Alberto, Mirisola, Alexandra, Fleischmann, Alexios, Arvanitis, Anabel, Belaus, Andree, Hartanto, Andrej, Findor, Andrew, Thomas, Anna, Wlodarczyk, Anni, Sternisko, Anthony, Lantian, Anton, Kuhberger, Aurélien, Graton, Bana, Bashour, Barnaby, Dixson, Bastian, Jaeger, Bastien, Trémolière, Benjamin, Becker, Benjamin, Brown, Biljana, Gjoneska, Biljana, Jokić, Bill, Shi, Carlota, Batres, Carmel, Levitan, Cecilia, Reyna, Charlotte, Hudson, Christina, Shane-Simpson, Christoph, Schild, Christopher, Castille, Carmelo, Cubillas, Daniel, Storage, Danielle, Ochoa, Danka, Purić, David, Moreau, Diego, Reinero, Don, Zhang, Dustin, Calvillo, Elif, Burak, Elisa, Puvia, Elizabeth, Harris, Elke, Lange, Ennio, Bilancini, Erica, Musser, Erin, Buchanan, Ernest, Baskin, Evgeniya, Hristova, Fanny, Lalot, Fatih, Bayrak, Fei, Xin, Fernando, Ruiz-Dodobara, Francesca, Dumančić, Gabriela, Marcu, Gilad, Feldman, Halil Emre Kocalar, Ian, Stephen, Iris, Žeželj, Ivy, Lau, Jackson, Lu, Jan, Röer, Jared, Celniker, Jasper, Hidding, Jennifer, Lenz, Jerome, Olsen, Jin, Goh, Jordan, Wagge, Jordane, Boudesseul, Joris, Lammers, Gwenaël, Kaminski, Karolina, Ścigała, Katarzyna, Rybus, Kathleen, Schmidt, Keith, Kendrick, Kevin, Tiede, Kim, Peters, Kimberley, Hill, Krystian, Barzykowski, Kyle, Susa, Laura, Stevens-Wilson, Lauren Victoria Tunstead, Leigh Ann Vaughn, Leigh, Wilton, Ljiljana, Lazarević, Luis, Eudave, Luisa, Batalha, Maja, Becker, Marietta, Papadatou-Pastou, Marijke, Leliveld, Mario, Gollwitzer, Mariola, Paruzel-Czachura, Martin, Voracek, Mathias, Twardawski, Maurice, Grinberg, Michael, Mensink, Michal, Parzuchowski, Miguel, Vadillo, Mirjana, Tonković, Miroslav, Sirota, Nada, Pop-Jordanova, Nate, Carnes, Neil, McLatchie, Nicholas, Owsley, Niklas, Steffens, Onurcan, Yilmaz, Panagiotis, Mitkidis, Pavol, Kačmár, Philip, Pärnamets, Raluca, Szekely-Copîndean, F. Ribeiro M. F., Richard, Huskey, Rizqy Amelia Zein, Samuel, Lins, Sara Álvarez Solas, Sarah, Wood, Sean, Mackinnon, Shan, Gao, Sinan, Alper, Stefan, Czoschke, Stefan, Stieger, Steve, Janssen, Sumaya, Albalooshi, Susann, Fiedler, Sylwia, Adamus, Thomas Rhys Evans, Tiago Jessé Souza De Lima, Trent, Lynds, William, Chopik, Xin, Liu, Zahir, Vally, Zoe, Magraw-Mickelson, Christopher, Chartier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______310::392f9dbd677af64074ca145deffaa036
http://hdl.handle.net/2158/1264706

A Bayesian Spatiotemporal Analysis of Pediatric Group A Streptococcal Infections

Autor: Angela Wang, Andrew M. Fine, Mark Janko, Lise E. Nigrovic, Paul M. Lantos, Erin Buchanan

Publikováno v: Open Forum Infectious Diseases

Background Pharyngitis due to group A Streptococcus (GAS) is a common pediatric infection. Physicians might diagnose GAS pharyngitis more accurately when given biosurveillance information about GAS activity. The availability of geographic GAS testing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df118a6f40cc3d6e91985651266f3e63
http://europepmc.org/articles/PMC6918452

Heißes Verlangen im ewigen Eis - Shadows of Love

Autor: Erin Buchanan

Der frischgebackenen Klimaforscherin Anouk bietet sich eine einmalige Chance: Sie darf mit einem Forscherteam in die Antarktis fliegen, um wissenschaftliche Untersuchungen durchzuführen. Schon auf dem Flug bemerkt sie den attraktiven aber schweigsam