Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Eriks Rozners"'
Publikováno v:
ACS Omega, Vol 9, Iss 6, Pp 7249-7254 (2024)
Externí odkaz:
https://doaj.org/article/29a4245eec9a44df97f51060f3f373eb
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33914- (2024)
The highly structured nature of the SARS-CoV-2 genome provides many promising antiviral drug targets. One particularly promising target is a cis-acting RNA pseudoknot found within a critical region called the frameshifting stimulatory element (FSE).
Externí odkaz:
https://doaj.org/article/c2accd011a9d45c6bfefaa2365ece001
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 1641-1688 (2021)
Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a most dramatic departure from the native structure of DNA. The present review summarizes 30 years of research on PNA’s chemistry, optimization of structure and f
Externí odkaz:
https://doaj.org/article/0136f8ae13954868a0c39cb0a71d2dcc
Autor:
Christopher A. Ryan, Eriks Rozners
Publikováno v:
ACS Omega, Vol 5, Iss 44, Pp 28722-28729 (2020)
Externí odkaz:
https://doaj.org/article/2356303416d942eaaa70250e2403d8b3
Publikováno v:
Applied Sciences, Vol 11, Iss 8, p 3594 (2021)
Nucleic acids not only store genetic information in their primary sequence but also exhibit biological functions through the formation of their unique structures [...]
Externí odkaz:
https://doaj.org/article/28ae4b121ab54e72808a7109641cec17
Publikováno v:
Journal of Nucleic Acids, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/e8df3f99bdf044c6b4b2a7567446a18d
Autor:
Eriks Rozners
Publikováno v:
Journal of Nucleic Acids, Vol 2012 (2012)
Peptide nucleic acid (PNA) has become an extremely powerful tool in chemistry and biology. Although PNA recognizes single-stranded nucleic acids with exceptionally high affinity and sequence selectivity, there is considerable ongoing effort to furthe
Externí odkaz:
https://doaj.org/article/12071b8a84f6463d95594104ac1e59ae
Publikováno v:
Journal of the American Chemical Society. 145:10497-10504
Autor:
Eriks Rozners
Publikováno v:
Journal of the American Chemical Society. 144:12584-12594
CRISPR (clustered, regularly interspaced, short palindromic repeats) has become a cutting-edge research method and holds great potential to revolutionize biotechnology and medicine. However, like other nucleic acid technologies, CRISPR will greatly b
Publikováno v:
ACS Chem Biol
The development of CRISPR-Cas9 mediated gene editing technology is revolutionizing molecular biology, biotechnology, and medicine. However, as with other nucleic acid technologies, CRISPR would greatly benefit from chemical modifications that optimiz