Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eriko Sugata"'
Autor:
Yui Sokuza, Mariko Onishi, Toshifumi Tsujiuchi, Kyoko Shimizu, Chiharu Mori, Tomoki Nishikawa, Mariko Saito, Eriko Sugata
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 638:133-138
Mutations in the mitochondrial DNA (mtDNA) displacement loop (D-loop) region were investigated to clarify the possible molecular mechanisms underlying the development of lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine (BHP) in rats. Male Wi
Autor:
Kyoko Shimizu, Chiharu Mori, Eriko Sugata, Tomoki Nishikawa, Toshifumi Tsujiuchi, Yui Sokuza, Kanya Honoki, Mariko Onishi
Publikováno v:
Cancer Science. 98:1318-1322
The authors investigated the DNA methylation patterns of the E-cadherin, Connexin 26 (Cx26), Rassf1a and c-fos genes in the early phase of rat hepatocarcinogenesis induced by a choline-deficient L-amino acid-defined (CDAA) diet. Six-week-old F344 mal
Autor:
Hiromasa Fujii, Kyoko Shimizu, Mariko Onishi, Eriko Sugata, Toshifumi Tsujiuchi, Kanya Honoki
Publikováno v:
Biochemical and Biophysical Research Communications. 353:522-526
To determine if the Tslc1 gene is involved in pancreatic carcinogenesis, the expression level of Tslc1 and the DNA methylation status of its 5' upstream region were investigated in pancreatic duct adenocarcinomas (PDAs) induced in hamsters by N-nitro
Autor:
Mariko Onishi, Kanya Honoki, Toshifumi Tsujiuchi, Kyoko Shimizu, Eriko Sugata, Midori Yoshida, Mayumi Fujii
Publikováno v:
Journal of Toxicologic Pathology. 20:65-69
Epidermal growth factor receptor (EGFR), a receptor protein tyrosine kinase, is a transmembrane protein. Recent studies indicate that mutations in the gene encoding EGFR are present in several human cancers. To assess the involvement of these mutatio
Autor:
Eriko Sugata, Hiromasa Fujii, Kyoko Shimizu, Mariko Onishi, Tomomi Masaoka, Kanya Honoki, Toshifumi Tsujiuchi
Publikováno v:
Cancer science. 98(7)
To assess the involvement of the TSLC cascade in hepatocarcinogenesis, we investigated the expression and DNA methylation patterns of the genes Tslc1 and Dal-1 in hepatocellular carcinomas (HCC) induced using N-nitrosodiethylamine (DEN) in rats. Six-
Autor:
Kyoko Shimizu, Mariko Onishi, Eriko Sugata, Tomomi Masaoka, Toshifumi Tsujiuchi, Hiromasa Fujii, Kanya Honoki
Publikováno v:
Molecular carcinogenesis. 46(10)
DAL-1 (differentially expressed in adenocarcinoma of the lung) is an actin-binding protein that has been shown to suppress growth in lung cancer cells. Recently, inactivation of the gene encoding DAL-1 due to hypermethylation has been found in severa
Autor:
Hiromasa Fujii, Toshifumi Tsujiuchi, Kyoko Shimizu, Kanya Honoki, Mariko Onishi, Yumi Itsuzaki, Eriko Sugata
Publikováno v:
Molecular carcinogenesis. 46(4)
We investigated DNA methylation patterns of E-cadherin and Connexin26 (Cx26) genes in rat hepatocellular carcinomas (HCCs) induced by a choline-deficient L-Amino Acid-defined (CDAA) diet. Six-wks-old F344 male rats were continuously fed with a CDAA d
Autor:
Hiromasa Fujii, Eriko Sugata, Kyoko Shimizu, Toshifumi Tsujiuchi, Toshio Mori, Kanya Honoki, Mariko Onishi, Nobuyuki Fukushima
Publikováno v:
Biochemical and biophysical research communications. 349(3)
Lysophosphatidic acid (LPA) is a bioactive phospholipid that stimulates cell proliferation, migration, and protects cells from apoptosis. It interacts with specific G protein-coupled transmembrane receptors. Recently, it has been reported that altera