Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Eriko Michishita"'
Autor:
Yuanxin Xi, Eriko Michishita-Kioi, Matthew F. Barber, Mitomu Kioi, Or Gozani, Zarmik Moqtaderi, Kevin Struhl, Silvana Paredes, Nicolas L. Young, Katrin F. Chua, Wei Li, Ruth I. Tennen, Benjamin A. Garcia, Kaifu Chen, Luisa Tasselli
Publikováno v:
Nature
Sirtuin proteins regulate diverse cellular pathways that influence genomic stability, metabolism and ageing. SIRT7 is a mammalian sirtuin whose biochemical activity, molecular targets and physiological functions have been unclear. Here we show that S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf1011141c37cce1a15f72991e2bbcd
http://europepmc.org/articles/PMC3412143
http://europepmc.org/articles/PMC3412143
Autor:
Rika Kusumoto, Peggie Cheung, Tiara L.A. Kawahara, Hesed Padilla-Nash, Katrin F. Chua, Eriko Michishita, Ronald A. McCord, Elisabeth Berber, Mara Damian, Howard Y. Chang, J. Carl Barrett, Or Gozani, Vilhelm A. Bohr, Mitomu Kioi, Thomas Ried
Publikováno v:
Nature. 452:492-496
The Sir2 deacetylase regulates chromatin silencing and lifespan in Saccharomyces cerevisiae1,2. In mice, deficiency for the Sir2 family member SIRT6 leads to a shortened lifespan and a premature ageing-like phenotype3. However, the molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3dd5f08f6b0a446ae28ef563c6ff143
https://doi.org/10.1038/nature06736
https://doi.org/10.1038/nature06736
Autor:
Nilotpal Roy, Eriko Michishita-Kioi, Shinji Tanaka, Jonathan R. Pollack, Elisabeth Berber, Misato Aonuma, Katrin F. Chua, Shivani Malik, Lidia Villanova
Publikováno v:
Scientific Reports
Metastasis is responsible for over 90% of cancer-associated mortality. In epithelial carcinomas, a key process in metastatic progression is the epigenetic reprogramming of an epithelial-to-mesenchymal transition-like (EMT) change towards invasive cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784d90c2436bdd33070feeee264c5555
Publikováno v:
Cancer Letters. 239:71-77
The microcell-mediated transfer of a normal human chromosome 3 induces replicative senescence in otherwise immortal renal cell carcinoma cells. To identify the genes involved in the chromosome 3-induced cellular mortality, we previously performed a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9742786ed1c4dfb81d6c0ebbba9aff44
https://doi.org/10.1016/j.canlet.2005.07.028
https://doi.org/10.1016/j.canlet.2005.07.028
Autor:
Eriko, Michishita1, Nakabayashi, Kazuhiko1, Suzuki, Toshikazu1, Kaul, Sunil C.2, Ogino, Hideki1, Fujii, Michihiko1, Mitsui, Youji2, Ayusawa, Dai1
Publikováno v:
Journal of Biochemistry. 1999, Vol. 126 Issue 6, p1052-1059. 8p.
Autor:
Izumi Horikawa, Richard J. Hodes, Y. Jeffrey Chiang, Vladimir Larionov, Sun-Hee Leem, Tricia Patterson, Lionel Feigenbaum, J. Carl Barrett, Eriko Michishita
Publikováno v:
Proceedings of the National Academy of Sciences. 102:18437-18442
In vivo expression of human telomerase is significantly different from that of mouse telomerase. To assess the basis for this difference, a bacterial artificial chromosome clone containing the entire hTERT (human telomerase reverse transcriptase) gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0b8d1f349210e2a44314e94f715d63
https://doi.org/10.1073/pnas.0508964102
https://doi.org/10.1073/pnas.0508964102
Autor:
Izumi Horikawa, Abhik Datta, Mirdad Kazanji, Janitzia C. Sigler-Nicot, J. Carl Barrett, Christophe Nicot, Eriko Michishita, Uma Sinha-Datta, Megan Brown
Publikováno v:
Blood. 104:2523-2531
In immortal cells, the existence of a mechanism for the maintenance of telomere length is critical. In most cases this is achieved by the reactivation of telomerase, a cellular reverse transcriptase that prevents telomere shortening. Here we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ee8b087cde75e303c7f00cedb631c6
https://doi.org/10.1182/blood-2003-12-4251
https://doi.org/10.1182/blood-2003-12-4251
Publikováno v:
Cell. 148:387-389
Resveratrol, a polyphenol in red wine, has been reported as a calorie restriction mimetic with potential antiaging and antidiabetogenic properties. It is widely consumed as a nutritional supplement, but its mechanism of action remains a mystery. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23499ea1d7ea11f8dc607a9aede67aa4
https://doi.org/10.1016/j.cell.2012.01.032
https://doi.org/10.1016/j.cell.2012.01.032
Publikováno v:
Experimental Cell Research. 276:174-184
5-Bromodeoxyuridine induces a senescence-like phenomenon in mammalian cells. This effect was dramatically potentiated by AT-binding ligands such as distamycin A, netropsin, and Hoechst 33258. The genes most remarkably affected by these ligands includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0068b0e7a37183edcfaa07b63c331ba
https://doi.org/10.1006/excr.2002.5524
https://doi.org/10.1006/excr.2002.5524
Autor:
Michihiko Fujii, Toshikazu Suzuki, Eriko Michishita, Mikako Yaginuma, Dai Ayusawa, Hideki Ogino, Takeshi Oishi
Publikováno v:
Experimental Cell Research. 266:53-63
An ectopic gene integrated in the host genome is occasionally silenced due to a position effect of its adjacent chromatin structure. We found that 5-bromodeoxyuridine clearly activated such a transgene in HeLa cells. The transgene was also activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7809b2122da7213b8e693fcd0efdc9aa
https://doi.org/10.1006/excr.2001.5194
https://doi.org/10.1006/excr.2001.5194