Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Eriko Katsuta"'
Publikováno v:
Cancers, Vol 16, Iss 4, p 683 (2024)
PIEZO1 plays a crucial role in the human body as a mechanosensory ion channel. It has been demonstrated that PIEZO1 is important in tissue development and regulating many essential physiological processes. Studies have suggested that the PIEZO1 ion c
Externí odkaz:
https://doaj.org/article/b3ebf740e92043bbb744a0dc1c191560
Autor:
Eriko Katsuta, Mateusz Opyrchal
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/605b6e07445a4d05822fef4d4a57ad0b
Autor:
Eriko Katsuta, Kazuaki Takabe, Marija Vujcic, Philip A. Gottlieb, Tao Dai, Arnaldo Mercado-Perez, Arthur Beyder, Qingfei Wang, Mateusz Opyrchal
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9909 (2022)
Background: Mechanically gated PIEZO channels lead to an influx of cations, activation of additional Ca2+ channels, and cell depolarization. This study aimed to investigate PIEZO2’s role in breast cancer. Methods: The clinical relevance of PIEZO2 e
Externí odkaz:
https://doaj.org/article/feb3eaebe3f94456952378ab47d0d4c6
Autor:
Jianliang Zhang, Irwin H. Gelman, Eriko Katsuta, Yuanzi Liang, Xue Wang, Jun Li, Jun Qu, Li Yan, Kazuaki Takabe, Steven N. Hochwald
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 1, Pp 37-60 (2019)
Background & Aims: Most targeted therapies against cancer are designed to block growth factor–stimulated oncogenic growth. However, response rates are low, and resistance to therapy is high. One mechanism might relate to the ability of tumor cells
Externí odkaz:
https://doaj.org/article/74e2c81b333044c0b4f350fb137465bb
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Cytotoxic T-lymphocyte (CTL) infiltration into tumor is a positive prognostic factor in breast cancer. High tumor mutational burden (TMB) is also considered as a predictor of tumor immunogenicity and response to immunotherapy. However, it
Externí odkaz:
https://doaj.org/article/80cfe9ae98ee4793b4b8e7a18d0ecade
Autor:
Yuki Hirose, Masayuki Nagahashi, Eriko Katsuta, Kizuki Yuza, Kohei Miura, Jun Sakata, Takashi Kobayashi, Hiroshi Ichikawa, Yoshifumi Shimada, Hitoshi Kameyama, Kerry-Ann McDonald, Kazuaki Takabe, Toshifumi Wakai
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Lymphatic metastasis is known to contribute to worse prognosis of biliary tract cancer (BTC). Recently, sphingosine-1-phosphate (S1P), a bioactive lipid mediator generated by sphingosine kinase 1 (SPHK1), has been shown to play an important
Externí odkaz:
https://doaj.org/article/7c3beab2d533479e8cf1a7cfa2bff92e
Autor:
Aparna Maiti, Ichiro Okano, Masanori Oshi, Maiko Okano, Wanqing Tian, Tsutomu Kawaguchi, Eriko Katsuta, Kazuaki Takabe, Li Yan, Santosh K. Patnaik, Nitai C. Hait
Publikováno v:
Cancers, Vol 13, Iss 11, p 2641 (2021)
Due to the heterogeneous nature of breast cancer, metastasis organotropism has been poorly understood. This study assessed the specific cancer-related gene expression changes occurring with metastatic breast cancer recurrence to distant organs compar
Externí odkaz:
https://doaj.org/article/9a2cd50883cb466c83b0487cc9a70852
Autor:
Sayeh Saravi, Eriko Katsuta, Jeyarooban Jeyaneethi, Hasnat A. Amin, Matthias Kaspar, Kazuaki Takabe, George Pados, Fotios Drenos, Marcia Hall, Emmanouil Karteris
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 9, p 2844 (2020)
Background: H2AX can be of prognostic value in breast cancer, since in advanced stage patients with high levels, there was an association with worse overall survival (OS). However, the clinical relevance of H2AX in ovarian cancer (OC) remains to be e
Externí odkaz:
https://doaj.org/article/5a94203879234cc0aee758c9a80b0584
Autor:
Yoshihisa Tokumaru, Masanori Oshi, Eriko Katsuta, Li Yan, Jing Li Huang, Masayuki Nagahashi, Nobuhisa Matsuhashi, Manabu Futamura, Kazuhiro Yoshida, Kazuaki Takabe
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5744 (2020)
Cancer-associated adipocytes are known to cause inflammation, leading to cancer progression and metastasis. The clinicopathological and transcriptomic data from 2256 patients with breast cancer were obtained based on three cohorts: The Cancer Genome
Externí odkaz:
https://doaj.org/article/2726709d869e4f68b2b1fe0ec8a53dec
Autor:
Hideo Takahashi, Eriko Katsuta, Li Yan, Yoshihisa Tokumaru, Matthew H.G. Katz, Kazuaki Takabe
Publikováno v:
Cancers, Vol 12, Iss 8, p 2033 (2020)
Lymphovascular invasion (LVI) is an aggressive pathologic feature and considered a risk factor for distant metastasis. We hypothesized that pancreatic ductal adenocarcinomas (PDACs) with LVI are associated with shorter survival, as well as aggressive
Externí odkaz:
https://doaj.org/article/fc8aa9201b6c48e09c3f15451daae0ae