Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Eriketi Z. Loizidou"'
Publikováno v:
RSC Medicinal Chemistry. 14:573-582
A new class of competitive proteasome inhibitors was identified from screening of the ZINC library of natural products. Structure–activity studies highlighted the importance of hydrophobic interactions in enhanced binding affinity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5466b0845c246df241e052104d16c02
https://doi.org/10.1039/d2md00404f
https://doi.org/10.1039/d2md00404f
For almost two decades, scientists have been exploring the use of nanoparticles as drug vesicles capable of protecting their cargo and deliver it to the target site while evading detection by the body. However, their translation to clinical use has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82de5b41cb0d04c783d0a1954c2a4230
https://eprints.mdx.ac.uk/33546/7/d1ma00135c_VoR.pdf
https://eprints.mdx.ac.uk/33546/7/d1ma00135c_VoR.pdf
Autor:
Rachel E. Sully, Adrian Gh. Podoleanu, Vladimir Gubala, Colin J. Moore, Eriketi Z. Loizidou, Hemda Garelick
Publikováno v:
Analytical methods : advancing methods and applications. 13(30)
The fast-advancing progress in the research of nanomedicine and microneedles application in the past two decades have suggested that the combination of the two concepts could help to overcome some of the challenges we are facing in healthcare. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59776c847466579806567e42a159446
https://pubmed.ncbi.nlm.nih.gov/34313266
https://pubmed.ncbi.nlm.nih.gov/34313266
Publikováno v:
Chemical Physics. 550:111295
Ethanol/water mixtures have served as a model to study the hydrophobic effect and the formation of clathrate and other cage like water formations around the hydrophobic end of ethanol. We have studied the evolution of FTIR-ATR spectra of ethanol/wate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582a6a15cfdc8f144a2002d1d47c91c4
https://doi.org/10.1016/j.chemphys.2021.111295
https://doi.org/10.1016/j.chemphys.2021.111295
Publikováno v:
Chemical Biology & Drug Design.
Inhibitors of the proteasome have found broad therapeutic applications; however, they show severe toxicity due to the abundance of proteasomes in healthy cells. In contrast, inhibitors of the immunoproteasome, which is upregulated during disease stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a03730f3de63ab1ac603e5ab2fff2e1
https://doi.org/10.1111/cbdd.13539
https://doi.org/10.1111/cbdd.13539
Autor:
Johnny Ashton-Barnett, Nicholas T. Inoue, David Anthony Barrow, Christopher John Allender, Eriketi Z. Loizidou
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 107:1-6
Computerized tomography scan (CT scan) imaging and finite element analysis were employed to investigate how the geometric composition of microneedles affects their mechanical strength and penetration characteristics. Simulations of microneedle arrays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecb703b9641cb8633a11b8b28c0ad25
https://doi.org/10.1016/j.ejpb.2016.06.023
https://doi.org/10.1016/j.ejpb.2016.06.023
Publikováno v:
Carbon. 146:369-370
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::870f6636bd0080c59a9be0b0c33fd1c3
https://doi.org/10.1016/j.carbon.2019.01.104
https://doi.org/10.1016/j.carbon.2019.01.104
Publikováno v:
Journal of Molecular Recognition. 24:678-686
In the present work, a combination of binding studies and molecular docking were employed to demonstrate drug encapsulation and host-guest chemistry in self-assembled micelles consisting of amphiphilic terpolymers. The terpolymer is composed of poly(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539c3ac5c332935456dadb59dc38f820
https://doi.org/10.1002/jmr.1098
https://doi.org/10.1002/jmr.1098
Autor:
Eriketi Z. Loizidou, John McCrory, David Anthony Barrow, Mark Jonathan Eaton, Nicholas Williams, Samuel Lewin Evans, Christopher John Allender
Dissolving microneedles are especially attractive for transdermal drug delivery as they are associated with improved patient compliance and safety. Furthermore, microneedles made of sugars offer the added benefit of biomolecule stabilisation making t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b12b345d7bc35f13fe1b09f283023f9
Autor:
Kyriacos C. Nicolaou, Theocharis V. Koftis, Yoichi M. A. Yamada, Michael O. Frederick, Eriketi Z. Loizidou, Goran Petrovic, Kevin P. Cole
Publikováno v:
Chemistry – An Asian Journal. 1:245-263
The naturally occurring but scarce marine neurotoxins azaspiracids-1, -2, and -3 have been synthesized from five key building blocks by a convergent strategy that involved dithiane and Stille coupling reactions. The ABCD fragments were constructed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce21483f99240c61bfe3a9b67ef1600e
https://doi.org/10.1002/asia.200600059
https://doi.org/10.1002/asia.200600059