Association between vitamin D receptor polymorphisms, tight junction proteins and clinical features of adult patients with atopic dermatitis

Autor: Teresa Grieco, Elisa Moliterni, Giovanni Paolino, Camilla Chello, Alvise Sernicola, Colin Gerard Egan, Fabrizio Nannipieri, Santina Battaglia, Marina Accoto, Erika Tirotta, Silvia Trasciatti, Silvano Bonaretti, Simona Nencioni, Elena Biasci, Giovanni Pellacani, Stefano Calvieri

Publikováno v: Dermatology Practical & Conceptual, Vol 14, Iss 3 (2024)

Background: Few studies have explored the intricate connections between vitamin D receptor (VDR) gene polymorphisms, VDR, tight junction (TJ) protein expression and clinical features of atopic dermatitis (AD). Methods: From 43 adult AD patients, VD

Externí odkaz: https://doaj.org/article/f5c7a7e7b4c34d579d8dbc16f0dbea9e

The flavonoid compound apigenin prevents colonic inflammation and motor dysfunctions associated with high fat diet-induced obesity.

Autor: Daniela Gentile, Matteo Fornai, Rocchina Colucci, Carolina Pellegrini, Erika Tirotta, Laura Benvenuti, Cristina Segnani, Chiara Ippolito, Emiliano Duranti, Agostino Virdis, Sara Carpi, Paola Nieri, Zoltán H Németh, Laura Pistelli, Nunzia Bernardini, Corrado Blandizzi, Luca Antonioli

Publikováno v: PLoS ONE, Vol 13, Iss 4, p e0195502 (2018)

Apigenin can exert beneficial actions in the prevention of obesity. However, its putative action on obesity-associated bowel motor dysfunctions is unknown. This study examined the effects of apigenin on colonic inflammatory and motor abnormalities in

Externí odkaz: https://doaj.org/article/35c71a87808b48089e4b35a8ee37379a

Small bowel protection against NSAID-injury in rats: Effect of rifaximin, a poorly absorbed, GI targeted, antibiotic

Autor: Emilia Ghelardi, Matteo Fornai, Carolina Pellegrini, Marina Flaibani, Erika Tirotta, Deborah Sacco, Carmelo Scarpignato, Cecilia Renzulli, Rocchina Colucci, Corrado Blandizzi, Alessia Bartalucci, Gianfranco Natale, Luca Antonioli

Publikováno v: Pharmacological Research. 104:186-196

Nonsteroidal anti-inflammatory drugs, besides exerting detrimental effects on the upper digestive tract, can also damage the small and large intestine. Although the underlying mechanisms remain unclear, there is evidence that enteric bacteria play a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6867d2f025b12682120c6e7c99995fb
https://doi.org/10.1016/j.phrs.2015.12.031

Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention

Autor: Elena Piccoli, Gianfranco Natale, Matteo Fornai, Emilia Ghelardi, Cecilia Renzulli, Carmelo Scarpignato, Carolina Pellegrini, Corrado Blandizzi, Federica Fulceri, Laura Benvenuti, Daniela Gentile, Luca Antonioli, Gloria Lopez-Castejon, Erika Tirotta, Pablo Palazón-Riquelme, Rocchina Colucci

Publikováno v: Frontiers in Pharmacology
Colucci, R, Pellegrini, C, Fornai, M, Tirotta, E, Antonioli, L, Renzulli, C, Ghelardi, E, Piccoli, E, Gentile, D, Benvenuti, L, Natale, G, Fulceri, F, Palazón-Riquelme, P, López-Castejón, G, Blandizzi, C & Scarpignato, C 2018, ' Pathophysiology of NSAID-associated intestinal lesions in the rat : Luminal bacteria and mucosal inflammation as targets for prevention ', Frontiers in Pharmacology, vol. 9, no. NOV, 01340 . https://doi.org/10.3389/fphar.2018.01340
Frontiers in Pharmacology, Vol 9 (2018)

Non-steroidal anti-inflammatory drugs (NSAIDs) can damage the small intestine, mainly through an involvement of enteric bacteria. This study examined the pathophysiology of NSAID-associated intestinal lesions in a rat model of diclofenac-enteropathy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ad1c5c53f6043ddba1c307f92c94d6
http://europepmc.org/articles/PMC6281992

The flavonoid compound apigenin prevents colonic inflammation and motor dysfunctions associated with high fat diet-induced obesity

Autor: Zoltan H. Nemeth, Sara Carpi, Daniela Gentile, Laura Benvenuti, Matteo Fornai, Emiliano Duranti, Agostino Virdis, Laura Pistelli, Carolina Pellegrini, Nunzia Bernardini, Corrado Blandizzi, Chiara Ippolito, Luca Antonioli, Erika Tirotta, Rocchina Colucci, Cristina Segnani, Paola Nieri

Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0195502 (2018)

Background and purpose Apigenin can exert beneficial actions in the prevention of obesity. However, its putative action on obesity-associated bowel motor dysfunctions is unknown. This study examined the effects of apigenin on colonic inflammatory and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f7019afce5a37fb62756580588f751
http://hdl.handle.net/11568/920683